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Cardiology Research

The Department of Cardiology at Concord Hospital undertakes a wide range of research in all areas of cardiovascular medicine.

We undertake studies using data from our own patients and from patients around the country that allow us to identify ways of improving patient care. Patients with heart attacks, angina, fluid build-up related to the heart (heart failure), clots in the lungs, and heart rhythm disturbances are included in these studies.

Our Atherosclerosis and Vascular Biology laboratory research at the ANZAC Research Institute includes molecular research into how cells accumulate cholesterol to block arteries, how we can clear this cholesterol, and how clots form to cause heart attacks. 

Our research into the control of the microcirculation in patients having angiograms is studying how small blood vessels contribute to the blood supply of the heart. 

CONCORDANCE (ANZAC Research Institute)
A national registry for coronary care

The CONCORDANCE registry has been designed within a comparative effectiveness research (CER) framework to collect and report data from hospitals located in geographically diverse regions of Australia. Information including patient demographics, presenting characteristics, past medical history, in-hospital management and outcomes at six months and two years are entered into a web-based database using an electronic clinical record form (eCRF). Individual hospital information is returned to the sites in a real time confidential report detailing information on key performance indicator (KPI) process measures and outcomes benchmarked against the aggregated study cohort.

The CONCORDANCE registry is a clinician-driven initiative describing clinical care for ACS patients admitted to Australian hospitals. The registry generates high quality data which is fed back to clinicians, and key stakeholders in ACS care. Using a CER approach, the registry describes the translation of randomised trial evidence into practice and provides insights into strategies that could improve care and ultimately patient outcomes.

Our Research Team

Professor David Brieger Head of Department
Karice Hyun Research Staff
Tessa Garcia Research Staff

Selected Grants

Amount awarded Grant and project details
$7,913,500 Genentech, 2021-2023
Industry project grant. RESTORE-MI trial
Investigator: Yong A (CIC)
€6,000,000 EU Horizon 2020, 2020-2022
AFFECT-EU – precision screening for atrial fibrillation
Investigator: Freedman B
$5,000,000 NHMRC Synergy Grant, 2019-2024
SOLVE-CHD
Investigators: Redfern J (CIA), Brieger D (CIH)
$2,727,508 NHMRC – MRFF, 2022-25
Enhancing the electronic Medical record (eMR) to BolsteR Acute Coronary syndromE care (The EMBRACE Project)
Investigator: Brieger
$1,780,000 Medical Research Futures Fund (MRFF), 2021 – 2026
SAFER-AUS Screening for AF to prevent stroke
Investigator: Freedman B (CIA)
$760,000 NSW Ministry of Health Clinician Scientist grant, 2019-2022
Cholesterol efflux capacity in at risk populations
Investigator: Kritharides L
$750,000 NSW Ministry of Health Senior Scientist Capacity Building Grant, 2021-2024
Preventing Disabling Stroke from Unknown and Undertreated Atrial Fibrillation
Investigator: Freedman B
$250,000 George Institute NHMRC Program Seed Grant Funding, 2022-2023
Maximising the benefits of the next generation of BP measurement devices 
Investigator: Gnanenthiran, S
$250,000 George Institute NHMRC Program Seed Grant Funding, 2022-2023
Formative Research for Development of a Polypill-Based Implementation Strategy for Patients with Heart Failure with Reduced Ejection Fraction in Australia
Investigator: Gnanenthiran, S
$150,000 National Heart Foundation Postdoctoral Fellowship, 2022-2024
Drug repurposing in cardiovascular disease: strategies to improve outcomes and accelerate drug translation
Investigator: Gnanenthiran, S
$50,000 Abbott Vascular Project Grant, 2019-2022
Project grant for core lab activities
Investigator: Yong A (CIA)

Our Publications

2021

Ada C, Yong ASC. Assessment of the coronary microcirculation in the cardiac catheterisation laboratory. Vessel Plus, accepted 2021 VP-2021-51.
Allahwala UK, Ekmejian A, Mughal N, Brieger D, Nour D, Ciofani JL, et al. Impact of coronary artery bypass grafting (CABG) on coronary collaterals in patients with a chronic total occlusion (CTO). Int J Cardiovasc Imaging. 2021;37(12):3373-80.
Al-Obaidi, FR, Hutchings HA, Yong ASC, Al-Rubaiy L, Al-Farhan H, Al-Ali MH, Al-Kinani T, Al-Myahi M, Al-Kenzawi H, Al-Sudani N. Efficacy and safety outcomes of short duration antiplatelet therapy with early cessation of aspirin post percutaneous coronary intervention: a systematic review and meta-analysis. Current Cardiology Reviews 2021, 17(6): e051121190712.
Ayad M, Hyun K, D'Souza M, Redfern J, Gullick J, Ryan M, et al. Factors that influence whether patients with acute coronary syndromes undergo cardiac catheterisation. Med J Aust. 2021;214(7):310-7.
Becattini C., Maraziti G., Vinson D., Ng A.C.C., den Exter P.L., Cote B., Vanni S., Hakemi E.U., Khemasuwan D., Weekes A.J., Soares T.H., Ozsu S., Friz H.P., Erol S., Agnelli G., Jimenez D.. Right ventricle assessment in patients with pulmonary embolism at low-risk for death based on clinical models: an individual patient meta-analysis. European Heart Journal 2021; 42:3190-3199.
Benjamin EJ, Go AS, Desvigne-Nickens P, Anderson CD, Casadei B, Chen LY, Crijns H, Freedman B, Hills MT, Healey JS, Kamel H, Kim DY, Link MS, Lopes RD, Lubitz SA, McManus DD, Noseworthy PA, Perez MV, Piccini JP, Schnabel RB, Singer DE, Tieleman RG, Turakhia MP, Van Gelder IC, Cooper LS and Al-Khatib SM. Research Priorities in Atrial Fibrillation Screening: A Report From a National Heart, Lung, and Blood Institute Virtual Workshop. Circulation. 2021;143:372-388.
Bhatia KS, Sritharan HP, Chia J, Ciofani J, Nour D, Chui K, Vasanthakumar S, Jayadeva P, Kandadai D, Allahwala U, Bhagwandeen R, Brieger DB, Choong CYP, Delaney A, Dwivedi G, Harris B, Hillis G, Hudson B, Javorsky G, Jepson N, Kanagaratnam L, Kotsiou G, Lee A, Lo STH, MacIsaac AI, McQuillan BM, Ranasinghe I, Walton A, Weaver J, Wilson W, Yong A, Zhu J, van Gaal W, Kritharides L, Chow C, Bhindi R. Cardiac complications in patients hospitalised with COVID-19 in Australia. Heart Lung Circ 2021, Sep 1:S1443-9506(21)01193-8. PMID:34481762.
Bhatia KS, Sritharan HP, Ciofani J, Chia J, Allahwala UK, Chui K, Nour D, Vasanthakumar S, Khandadai D, Jayadeva P, Bhagwandeen R, Brieger D, Choong C, Delaney A, Dwivedi G, Harris B, Hillis G, Hudson B, Javorski G, Jepson N, Kanagaratnam L, Kotsiou G, Lee A, Lo ST, MacIsaac AI, McQuillan B, Ranasinghe I, Walton A, Weaver J, Wilson W, Yong ASC, Zhu J, Van Gaal W, Kritharides L, Chow CK, Bhindi R. Association of hypertension wth mortality in patients hospitalised with COVID-19. Open Heart 2021, Dec 8:e001853.
Bhatia KS, van Gaal W, Kritharides L, Chow CK, Bhindi R; AUS-COVID Investigators. The incidence of cardiac complications in patients hospitalised with COVID-19 in Australia: the AUS-COVID study. Med J Aust 2021, Sep, 215:279 Epub Aug 17, PMID:34405420.
Boriani G, Palmisano P, Malavasi VL, Fantecchi E, Vitolo M, Bonini N, Imberti JF, Valenti AC, Schnabel RB and Freedman B. Clinical Factors Associated with Atrial Fibrillation Detection on Single-Time Point Screening Using a Hand-Held Single-Lead ECG Device. Journal of clinical medicine. 2021;10.
Brieger D, Freedman B. Decoding stroke risk scores in atrial fibrillation: still more work to do. Eur Heart J. 2021;42(15):1486-8.
Carnicelli AP, Owen R, Pocock SJ, Brieger DB, Yasuda S, Nicolau JC, et al. Atrial fibrillation and clinical outcomes 1 to 3 years after myocardial infarction. Open Heart. 2021;8(2).
Cellar B, Butlin M, Tan I, Argha R, Yong ASC Alvolio A. Are Korotkoff sounds reliable markers for accurate estimation of systolic and diastolic pressure using brachial cuff sphygmomanometry? IEEE Transactions on Biomedical Engineering 2021;68(12): 3593-3601.
Chan NY, Orchard J, Agbayani MJ, Boddington D, Chao TF, Johar S, John B, Joung B, Krishinan S, Krittayaphong R, Kurokawa S, Lau CP, Lim TW, Linh PT, Long VH, Naik A, Okumura Y, Sasano T, Yan B, Raharjo SB, Hanafy DA, Yuniadi Y, Nwe N, Awan ZA, Huang H and Freedman B. 2021 Asia Pacific Heart Rhythm Society (APHRS) practice guidance on atrial fibrillation screening. Journal of Arrhythmia. 2021;38:31-49.
Cheng YY, Chow V, Brieger D, Yan TD, Kritharides L, Ng ACC. Outcomes of 16,436 patients requiring isolated aortic valve surgery: A statewide cohort study. Int J Cardiol, 2021 Mar 1;326:55-61. PMID 33181157.
Chew DP, Hyun K, Morton E, Horsfall M, Hillis GS, Chow CK, et al. Objective Risk Assessment vs Standard Care for Acute Coronary Syndromes: A Randomized Clinical Trial. JAMA Cardiol. 2021;6(3):304-13.
Ferguson C, Lowres N and Freedman B. Stroke Risk in Adults With Atrial Fibrillation According to Sex. Heart, lung & circulation. 2021;30:937-938.
Figtree G, Doyle K, Hsu MP, Freedman B. The Australian Cardiovascular Alliance (ACvA). Eur Heart J. 2021;42:8-10.
Freedman B and Lowres N. High-intensity atrial fibrillation screening to prevent stroke. Lancet. 2021;398:1465-1467.
Freedman B, Hindricks G, Banerjee A, Baranchuk A, Ching CK, Du X, Fitzsimons D, Healey JS, Ikeda T, Lobban TCA, Mbakwem A, Narasimhan C, Neubeck L, Noseworthy P, Philbin DM, Jr., Pinto FJ, Rwebembera J, Schnabel RB, Svendsen JH, Aguinaga L, Arbelo E, Bohm M, Farhan HA, Hobbs FDR, Martinez-Rubio A, Militello C, Naik N, Noubiap JJ, Perel P, Pineiro DJ, Ribeiro AL and Stepinska J. World Heart Federation Roadmap on Atrial Fibrillation - A 2020 Update. Glob Heart. 2021;16:41.
Gibbs H, Freedman B, Rosenqvist M, Virdone S, Mahmeed WA, Ambrosio G, Camm AJ, Jacobson B, Jerjes-Sanchez C, Kayani G, Oto A, Panchenko E, Ragy H, Kakkar AK and Investigators G-A. Clinical Outcomes in Asymptomatic and Symptomatic Atrial Fibrillation Presentations in GARFIELD-AF: Implications for AF Screening. The American journal of medicine. 2021;134:893-901 e11.
Giskes K, Lowres N, Li J, Orchard J, Hespe C and Freedman B. Atrial fibrillation self screening, management and guideline recommended therapy (AF SELF SMART): A protocol for atrial fibrillation self-screening in general practice. International journal of cardiology Heart & vasculature. 2021;32:100683.
Gnanenthiran SR, Agarwal, Patel A. Frontiers of Cardiovascular Polypills: From Atherosclerosis and Beyond. Trends in Cardiovascular Medicine. 2021. S1050-1738(21)00163-8 Schutte AE, Gnanenthiran SR, Rodgers A. An ISH-led prospective meta-analysis on RCTs of RAAS inhibitors in COVID-19 patients: A call for collaboration. HT News. March 2021.
Gnanenthiran SR, Borghi C, Burger D, Charchar F, Poulter NR, Schlaich M, Steckelings UM, Stergiou GS, Tomaszewski M, Unger T, Wainford RD, Williams B, Rodgers A, Schutte AE. A Prospective Meta-Analysis Protocol on Randomised Trials of Renin-Angiotensin System Inhibitors in Patients with Coronavirus Disease 2019 (COVID-19): An initiative of the International Society of Hypertension. BMJ Open. 2021. 11 (2), e043625.
Gnanenthiran SR, Gallagher M, Ridley L, Tang R, Kritharides L. Chronic occlusion of the thoracic aorta: a novel cause of pleuropericardial effusions and pancytopenia. J Vasc Surg Cases Innov Tech 2021, 7:540544 PMID:34401621.
Gwynn J, Gwynne K, Rodrigues R, Thompson S, Bolton G, Dimitropoulos Y, Dulvari N, Finlayson H, Hamilton S, Lawrence M, MacNiven R, Neubeck L, Rambaldini B, Taylor K, Wright D and Freedman B. Atrial Fibrillation in Indigenous Australians: A Multisite Screening Study Using a Single-Lead ECG Device in Aboriginal Primary Health Settings. Heart, lung & circulation. 2021;30:267-274.
Haghbayan H, Gale CP, Chew DP, Brieger D, Fox KA, Goodman SG, et al. Clinical Risk Prediction Models for the Prognosis and Management of Acute Coronary Syndromes. Eur Heart J Qual Care Clin Outcomes. 2021.
Hoskin S, Chow V, Brieger D, Kritharides L, Ng ACC. Trends in Acute Pulmonary Embolism Admission Rates and Mortality Outcomes in Australia 2002-2003 and 2017-2018: a retrospective cohort study. Thrombosis and Haemostasis 2021 Feb 28.doi: 10.1055/s-0041-1725932.
Hsu B, Korda R, Naganathan V, Lewis P, Ooi SY, Brieger D, et al. Burden of cardiovascular diseases in older adults using aged care services. Age Ageing. 2021;50(5):1845-9.
Hyun K, Negrone A, Redfern J, Atkins E, Chow C, Kilian J, et al. Gender Difference in Secondary Prevention of Cardiovascular Disease and Outcomes Following the Survival of Acute Coronary Syndrome. Heart Lung Circ. 2021;30(1):121-7.
Jiang Z, Ou C, Qian Y, Rehan R, Yong ASC. Coronary vessel segmentation using multiresolution and multiscale deep learning. Informatics in Medicine Unlocked 2021; 24:1-9.
Lee AH, Ng ACC, Yong ASC, Hyun K, Brieger D, Kritharides L, Chow V. Outcomes of 1,098 Patients Following Transcatheter Aortic Valve Implantation: A Statewide Population-Linkage Cohort Study. Heart Lung Circ. 2021 Mar 12:S1443-9506(21)00054-8. PMID: 3372248.
Lowres N and Freedman B. Population screening for atrial fibrillation to prevent stroke. Lancet. 2021;398:1463-1465.
Lowres N and Freedman B. Searching for atrial fibrillation post-stroke with prolonged monitoring: Do it early, but should we be looking for something else? International journal of cardiology Heart & vasculature. 2021;34:100819.
Lowres N, Giskes K and Freedman B. Next frontier in management of atrial fibrillation. Heart (British Cardiac Society). 2021;107:767-768.
Lowres N, Suwanwela NC, Chutinet A and Freedman B. Response to letter to the editor regarding: "Atrial fibrillation prevalence and risk profile from novel community-based screening in Thailand: A prospective multi-centre study". International journal of cardiology Heart & vasculature. 2021;33:100752.
Ma M, Hyun K, D'Souza M, Chew D, Brieger D. Missed Opportunities to Initiate Oral Anticoagulant in Atrial Fibrillation: Insights from Australian Acute Coronary Syndrome Registries. Heart Lung Circ. 2021.
Malavasi VL, Zoccali C, Brandi MC, Micali G, Vitolo M, Imberti JF, Mussi C, Schnabel RB, Freedman B and Boriani G. Cognitive impairment in patients with atrial fibrillation: Implications for outcome in a cohort study. Int J Cardiol. 2021;323:83-89.
Meier S, Yu C, Raju H, Naoum C. Incidental diagnosis of arrhythmogenic right ventricular cardiomyopathy on coronary computed tomography angiography in a septuagenarian. Eur Heart J. 2021 Mar 14;42(11):1117. doi: 10.1093/eurheartj/ehaa749. PMID: 33167003.
Nishi T, Murai T, Waseda K, Hirohata A, Yong ASC, Ng MKC, Amano T, Barbato E, Kakuta T, Fearon WF. Association of Microvascular Dysfunction With Clinical Outcomes in Patients with Non-flow Limiting Fractional Flow Reserve Measured after Percutaneous Coronary Intervention. International Journal of Cardiology heart & Vasculature 2021, 35:100833.
Parvaneh M, Witting PK, Ku J, Moradi T, Eroglu E, Freedman B, Sutherland GT, McCorkindale A, Guennewig B, Choowong P, Bell-Anderson K, Cooney G, Thomas SR and Eberhard J. Periodontitis induces endothelial dysfunction in mice. Sci Rep. 2021;11:14993.
Peng CQ, Lawson KD, Heffernan M, McDonnell G, Liew D, Lybrand S, Pearson SA, Cutler H, Kritharides L, Trieu K, Huynh Q, Usherwood T, Occhipinti JA. Gazing through time and beyond the health sector: insights from a system dynamics model of cardiovascular disease in Australia. PLos One 2021, Sep 30, 16:e0257760 doi:10.1371/journalpone.0257760.
Pennings G, Reddell C, Kockx M, Magda M, Chen V, Kritharides L. Rapid Platelet release of interleukin 1 b from human platelets is independent of NLRP3 and caspase. Thromb Haemost, 2021, June 25, doi:10.1055/s-0041-1731288 PMID 3417 1934.
Pennings GJ, Reddell CJ, Traini M, Campbell H, Chen V, Kritharides L. Colchicine inhibits ROS generation in response to glycoprotein VI stimulation. Sci Rep 2021, Jun 7, 11:11965. PMID 34099810.
Pocock S, Brieger DB, Owen R, Chen J, Cohen MG, Goodman S, et al. Health-related quality of life 1-3 years post-myocardial infarction: its impact on prognosis. Open Heart. 2021;8(1).
Rao A.C.A., Ng A.C.C., Sy R.W., Chia K.K.M., Hansen P.S., Chiha J., Kilian J., Kanagaratnam L.B.. Electrocardiographic QRS duration is influenced by body mass index and sex. IJC Heart & Vasculature 2021; 37:100884.
Ratwatte S, Hyun K, D'Souza M, Barraclough J, Chew DP, Shetty P, et al. Relation of Body Mass Index to Outcomes in Acute Coronary Syndrome. Am J Cardiol. 2021;138:11-9.
Ratwatte S, Kritharides L, Raju H. Autoadapt algorithm leading to left ventricular dyssynchrony and haemodynamic compromise. Eur Heart J Case Rep 2021, Oct, 5:ytab406.
Reddell CJ, Lau JK , Pennings GJ, Campbell H, Chen V, Kritharides L Circulating platelet-derived extracellular vesicles are decreased after remote ischemic preconditioning in patients with coronary disease: a randomized controlled trial. J Thromb Haemost 2021,19(10): 2605-2611.
Redwood E, Hyun. K, French JK, Kritharides L, Ryan M, Chew. DP, D'Souza M, Brieger DB. The influence of travelling to hospital by ambulance on reperfusion time and outcomes for patients with STEMI. Med J. Aust. 2021, doi 10.5694/mja2.51005 on line ahead of print 2/4/21.
Rehan R, Kempler E, McMaster K, Larnach G, Amos D, Elder A, Arnold R, Juergens C, Patel S, Weaver J, Ng M, Roy P, Yong A, Brieger D, Kritharides L, Adams M, Lowe HC. In hospital outcomes for high-risk percutaneous coronary intervention. In patients referred from a rural centre to metropolitan sites. Heart Lung Circ 2021, Aug 11:s1443-9506(21)01163-X PMID:34391688.
Sarkies MN, Robinson S, Briffa T, Duffy SJ, Nelson M, Beltrame J, et al. Applying a framework to assess the impact of cardiovascular outcomes improvement research. Health Res Policy Syst. 2021;19(1):67.
Schnabel RB, Wallenhorst C, Engler D, Blankenberg S, Pfeiffer N, Spruenker NA, Buettner M, Michal M, Lackner KJ, Munzel T, Wild PS, Martinez C, Freedman B and Gutenberg Health Study i. Refined atrial fibrillation screening and cost-effectiveness in the German population. Heart (British Cardiac Society). 2021.
Schutte AE, Gnanenthiran SR. Towards a better understanding of why cumulative blood pressure is such a strong predictor of cardiovascular outcomes. Hypertension. 2021. 78(5):1267-1269.
Snir A, Wilson MK, Ju LA, Zhao Y, Wong S, Khor L, Naoum C, Wong K, Keech A, Celermajer DS, Ng MK. Novel Pressure-Regulated Deployment Strategy for Improving the Safety and Efficacy of Balloon-Expandable Transcatheter Aortic Valves. JACC Cardiovasc Interv. 2021 Nov 22;14(22):2503-2515. doi: 10.1016/j.jcin.2021.08.037. Epub 2021 Oct 27.PMID: 34756539.
Stavrakis S, Elkholey K, Lofgren MM, Asad ZUA, Stephens LD and Freedman B. Screening for Atrial Fibrillation in American Indian Adults in a Tribal Primary Care Clinic. Journal of the American Heart Association. 2021;10:e020069.
Stocker TJ, Nühlen N, Schmermund A, Leipsic J, Grove EL, Deseive S, Bax JJ, Maurovich-Horvat P, Otton J, Hadamitzky M, Chen MY, Naoum C, Andreini D, Rubinshtein R, Massberg S, Hausleiter J. Impact of Dose Reduction Strategies on Image Quality of Coronary CTA in Real-World Clinical Practice: A Subanalysis of PROTECTION VI Registry Data. AJR Am J Roentgenol. 2021 Dec;217(6):1344-1352. doi: 10.2214/AJR.21.26007. Epub 2021 Jun 16.PMID: 34133193.
Suwanwela NC, Chutinet A, Autjimanon H, Ounahachok T, Decha-Umphai C, Chockchai S, Indrabhakti S, Kijpaisalratana N, Akarathanawat W, Travanichakul S, Kitjavijitre T, Vongvasinkul P, Kanacharoen I, Bunlikitkul TO, Charnwut S, Lowres N and Freedman B. Atrial fibrillation prevalence and risk profile from novel community-based screening in Thailand: A prospective multi-centre study. International journal of cardiology Heart & vasculature. 2021;32:100709.
Tam CS, Gullick J, Saavedra A, Vernon ST, Figtree GA, Chow CK, et al. Combining structured and unstructured data in EMRs to create clinically-defined EMR-derived cohorts. BMC Med Inform Decis Mak. 2021;21(1):91.
Tan JWC, Chew DP, Brieger D, Eikelboom J, Montalescot G, Ako J, et al. 2020 Asian Pacific Society of Cardiology Consensus Recommendations on Antithrombotic Management for High-risk Chronic Coronary Syndrome. Eur Cardiol. 2021;16:e26.
Tern PJW, Ho AKH, Sultana R, Ahn Y, Almahmeed W, Brieger D, et al. Comparative overview of ST-elevation myocardial infarction epidemiology, demographics, management, and outcomes in five Asia-Pacific countries: a meta-analysis. Eur Heart J Qual Care Clin Outcomes. 2021;7(1):6-17.
Tong A, Sorrell TC, Black AJ, Caillaud C, Chrzanowski W, Li E, Martinez-Martin D, McEwan A, Wang R, Motion A, Bedoya AC, Huang J, Azizi L, Eggleton BJ; COVID-19 Sensor Research Priority-Setting Investigators. Research priorities for COVID-19 sensor technology. Nat Biotechnol. 2021 Feb;39(2):144-147. PMID: 33462510 (Kritharides named co-author).
Tong S, Bloom J, Quinn S, Nasis A, Hiew C, Roberts-Thomson P, Adams H, Sriamareswaran R, Htun R, Wilson W, Stub D, van Gaal W, Howes L, Yeap A, Yip B, Wu S, Perera P, Collins N, Yong A, Bhindi R, Whitbourn R, Lee A, Premaratne M, Asrress K, Freeman M, Amerena J, Layland J. Colchicine in Patients With Acute Coronary Syndrome: 2 Year Follow-Up of the Australian COPS Randomized Clinical Trial. Circulation 2021;144(19) 1584-1586.
Vijayaratnam PRS, Fulker D, Kim Y.C, Brandt J, Yi J, Yong ASC, Kritharides. L, Simmons A, Barber T.J. Investigating the haemodynamics of myocardial bridging. Experiments in Fluids, 2021, 62, Article 86.
Wachter R and Freedman B. Subclinical Atrial Fibrillation and the Risk of Recurrent Ischemic Stroke. Thrombosis and haemostasis. 2021;121:697-699.
Watts GF, Sullivan DR, Hare DL, Kostner KM, Horton AE, Bell DA, Brett T, Trent RJ, Poplawski NK, Martin AC, Srinivasan S, Justo RN, Chow CK, Pang J; and members of the FH Australasia Network Consensus Working Group. Essentials of a new clinical practice guidance on familial hypercholesterolaemia for physicians. Int Med J 2021, May, 51, 769-779.
Watts GF, Sullivan DR, Hare DL, Kostner KM, Horton AE, Bell DA, Brett T, Trent RJ, Poplawski NK, Martin AC, Srinivasan S, Justo RN, Chow CK, Pang J; FH Australasia Network Consensus Working Group. Integrated guidance for enhancing he care of familial hypercholesterolaemia in Australia. Heart Lung Circ 2021 Mar;30(3):324-349.
Wong C, Nishi T, Yong A, Murai T, Kakuta T, Waseda K, Amano T, Hirohata A, Barbato E, Ng M, Fearon W. Discordance between the index of microcirculatory resistance and coronary flow reserve after percutaneous coronary intervention. JACC Cardiovasc Interv 2021; 14(21): 2412-2414
Wong CCY, Ng ACC, Ada C, Chow V, Fearon WF, Ng MKC, Kritharides L, Yong ASC.A real world comparison of outcomes between fractional flow reserve-guided versus angiography-guided percutaneous coronary intervention. PLoS One 2021, Dec 16, 16:e0259662.
Yong ASC, Pargaonkar VS, Wong CCY, Javadzdegan A, Yamada R, Tanaka S, Kimura T, Rogers IS, Sen I, Kritharides L, Schnittger I, Tremmel JA. Abnormal shear stress and residence time are associated with proximal coronary atheroma in the presence of myocardial bridging. Int J Cardiol 2021, Oct, 340:7-13.
Yu C, Brazete S, Gullick J, Garcia MT, Brieger D, Kritharides L, Naoum C, Ng ACC, Lowe HC. Long-term outcomes following rapid access chest pain clinic assessment: first Australian data. Heart Lung Circ 2021, Sep, 30:1309-1313.
Yu C, Ng ACC, Ridley L, , Kritharides L, Meier S, Yiannikas J, Naoum C. Incidentally identified coronary artery calcium on non-contrast chest CT predicts major adverse cardiac events among hospital inpatients Open Heart 2021Oct, 8:e001695.
Yu C, Ng ACC, Ridley L, Anjaria M, Meier S, Yiannikas J, Kritharides L, Naoum C. Incidentally identified coronary artery calcium on non-contrast CT scan of the chest predicts major adverse cardiac events among hospital inpatients. Open Heart. 2021 Oct;8(2):e001695. doi: 10.1136/openhrt-2021-001695.PMID: 34635575.
Zhang W, Chen Y, Miao C-Y, Huang Q-F, Sheng C-S, Shao S, Wang D, Xu S-K, Lei L, Zhang D, Chen Y-L, Hu L-X, Xia J-H, Ye X-F, Cheng Y-B, Wang Y, Guo Q-H, Li Y, Lowres N, Freedman B and Wang J-G. Quarterly versus annual ECG screening for atrial fibrillation in older Chinese individuals (AF-CATCH): a prospective, randomised controlled trial. The Lancet Healthy Longevity. 2021;2:e470-e478.
Zink MD, Mischke KG, Keszei AP, Rummey C, Freedman B, Neumann G, Tolksdorf A, Frank F, Wienstroer J, Kuth N, Schulz JB and Marx N. Screen-detected atrial fibrillation predicts mortality in elderly subjects. Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology. 2021;23:29-38.