A NSW Government website
The transplant unit at Royal Prince Alfred Hospital is the largest abdominal organ transplant centre in NSW and home to the Australian National Liver Transplant Unit. The department has many active research projects, primarily in the fields of organ preservation and regeneration, transplant oncology and clinical outcomes.
Surgeon and scientists with the surgical Liver Transplant Research Program conduct basic science research and clinical research directed at improving care before, during and after liver transplant for patients with liver failure and certain malignancies.
The RPA Translational Centre for Organ Assessment, Repair, and Optimisation (COARO) was established in 2018. The COARO has assembled a research team that is uniquely suited to integrate modern knowledge of organ perfusion4-6, bioengineering, ischemia-reperfusion injury, metabolism, and liver transplantation. The COARO is the first and only centre that has preserved human livers for up to 13 days under normothermic conditions.
| Dr Michael Crawford | Head of Department |
| Associate Professor Carlo Pulitano | Director of RPA Translational Centre for Organ Assessment, Repair, and Optimisation and the liver transplant oncology program |
| Associate Professor Jerome Laurence | Research lead in renal transplantation |
| Chuanmin Wang | Senior Hospital Scientist |
| Sumon Chanda | Perfusionist |
| Paul Yousif | Perfusionist |
| Daniel Babekuhl | PhD student |
| Dr Andrew Jacques | PhD student |
| Dr Soon Lau | PhD student |
| Dr Mark Ly | PhD student |
| Anita Niu | Masters student |
| Charles Risbey | PhD student |
| Victor Yu | Masters student |
| Amount awarded | Grant and project details |
|---|---|
| $150,000 | Royal Australasian College of Surgeons (RACS), 2022-2023 Development of an Automate system for Preservation of a Metabolically Active Liver For More Than 2 Weeks. Investigator: Pulitano C |
| $150,000 | Royal Australasian College of Surgeons (RACS), 2021-2022 Long term ex-vivo perfusion Investigator: Pulitano C |
| Alaimo L, Lima HA, Moazzam Z, Endo Y, Yang J, Ruzzenente A, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Kitago M, Pawlik TM. Development and Validation of a Machine-Learning Model to Predict Early Recurrence of Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2023 Sep;30(9):5406-5415. doi: 10.1245/s10434-023-13636-8. Epub 2023 May 20. |
| Alaimo L, Moazzam Z, Brown ZJ, Endo Y, Ruzzenente A, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM. Application of Hazard Function to Investigate Recurrence of Intrahepatic Cholangiocarcinoma After Curative-Intent Liver Resection: A Novel Approach to Characterize Recurrence. Ann Surg Oncol. 2023 Mar;30(3):1340-1349. doi: 10.1245/s10434-022-12463-7. Epub 2022 Aug 27. |
| Alaimo L, Moazzam Z, Endo Y, Lima HA, Butey SP, Ruzzenente A, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Kitago M, Kim A, Ejaz A, Beane J, Cloyd J, Pawlik TM. The Application of Artificial Intelligence to Investigate Long-Term Outcomes and Assess Optimal Margin Width in Hepatectomy for Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2023 Jul;30(7):4292-4301. doi: 10.1245/s10434-023-13349-y. Epub 2023 Mar 23. |
| Alaimo L, Moazzam Z, Endo Y, Lima HA, Ruzzenente A, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Pawlik TM. Long- Term Recurrence-Free and Overall Survival Differ Based on Common, Proliferative, and Inflammatory Subtypes After Resection of Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2023 Mar;30(3):1392-1403. doi: 10.1245/s10434-022-12795-4. Epub 2022 Nov 16. |
| Alaimo L, Moazzam Z, Lima HA, Endo Y, Ruzzenente A, Guglielmi A, Ratti F, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Popescu I, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Kitago M, Aucejo F, Sasaki K, Fields RC, Hugh T, Lam V, Pawlik TM. An attempt to establish and apply global benchmarks for liver resection of malignant hepatic tumors. Surgery. 2023 Dec;174(6):1384-1392. doi: 10.1016/j.surg.2023.08.024. Epub 2023 Sep 22. |
| Angelico R, Sensi B, Quaranta C, Orsi M, Parente A, Schlegel A, Tisone G, Manzia TM; Real-World Machine Perfusion Study Group. The impact of center volume on the utilization and outcomes of machine perfusion technology in liver transplantation: An international survey. Artif Organs. 2023 Nov;47(11):1773-1785. doi: 10.1111/aor.14635. Epub 2023 Aug 27. |
| Ealing IV, Lau NS, Cheung D, Peruch S, Agostinho N, Crawford M, Pulitano C. Safety of laparoscopic repair of incisional hernias in liver transplant recipients. Clin Transplant. 2023 Jun;37(6):e14969. doi: 10.1111/ctr.14969. Epub 2023 Mar 28. |
| Endo Y, Moazzam Z, Alaimo L, Lima HA, Munir MM, Shaikh CF, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Kitago M, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Pawlik TM. Predictive risk-score model to select patients with intrahepatic cholangiocarcinoma for adjuvant chemotherapy. HPB (Oxford). 2023 Feb;25(2):229-238. doi: 10.1016/j.hpb.2022.10.011. Epub 2022 Nov 3. |
| Endo Y, Moazzam Z, Lima HA, Alaimo L, Munir MM, Shaikh CF, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Kitago M, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Pawlik TM. The impact of tumor location on the value of lymphadenectomy for intrahepatic cholangiocarcinoma. HPB (Oxford). 2023 Jun;25(6):650-658. doi: 10.1016/j.hpb.2023.02.013. Epub 2023 Feb 22. |
| Endo Y, Moazzam Z, Woldesenbet S, Araujo Lima H, Alaimo L, Munir MM, Shaikh CF, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Kitago M, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Pawlik TM. Predictors and Prognostic Significance of Postoperative Complications for Patients with Intrahepatic Cholangiocarcinoma. World J Surg. 2023 Jul;47(7):1792-1800. doi: 10.1007/s00268-023-06974-x. Epub 2023 Apr 3. |
| Endo Y, Sasaki K, Moazzam Z, Lima HA, Alaimo L, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Kitago M, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Pawlik TM. Higher Tumor Burden Status Dictates the Impact of Surgical Margin Status on Overall Survival in Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2023 Apr;30(4):2023-2032. doi: 10.1245/s10434-022-12803-7. Epub 2022 Nov 17. |
| Jackson S, Combes A, Latif E, Tran M, Lam S, Gore N, Utsiwegota M, Mawson J, Smith L, Palma C, Laurence J, Crawford M, Pulitano C, Wyburn K, Chadban S, Leslie S, Vasilaras A. Laparoscopic donor nephrectomy-Technique and peri- operative outcomes in an Australian transplant center. Clin Transplant. 2023 May;37(5):e14945. doi: 10.1111/ctr.14945. Epub 2023 Feb 27. |
| Lau NS, Ly M, Dennis C, Ewenson K, Ly H, Huang JL, Cabanes-Creus M, Chanda S, Wang C, Lisowski L, Liu K, Kench J, McCaughan G, Crawford M, Pulitano C. Liver splitting during normothermic machine perfusion: a novel method to combine the advantages of both in-situ and ex-vivo techniques. HPB (Oxford). 2023 May;25(5):543-555. doi: 10.1016/j.hpb.2023.02.003. Epub 2023 Feb 8. |
| Lau NS, Ly M, Dennis C, Jacques A, Cabanes-Creus M, Toomath S, Huang J, Mestrovic N, Yousif P, Chanda S, Wang C, Lisowski L, Liu K, Kench JG, McCaughan G, Crawford M, Pulitano C. Long-term ex situ normothermic perfusion of human split livers for more than 1 week. Nat Commun. 2023 Aug 8;14(1):4755. doi: 10.1038/s41467-023-40154-8. |
| Ly M, Lau NS, McKenzie C, Kench JG, McCaughan G, Crawford M, Pulitano C. Does an Additional Bile Duct Flush With Low-viscosity Preservation Solution Reduce Bile Duct Injury? A Single-blinded Randomized Clinical Trial. Transplant Direct. 2023 Feb 8;9(3):e1443. doi: 10.1097/TXD.0000000000001443. |
| Ly M, Lau NS, McKenzie C, Kench JG, Seyfi D, Majumdar A, Liu K, McCaughan G, Crawford M, Pulitano C. Histological Assessment of the Bile Duct before Liver Transplantation: Does the Bile Duct Injury Score Predict Biliary Strictures? J Clin Med. 2023 Oct 27;12(21):6793. doi: 10.3390/jcm12216793. |
| Moazzam Z, Alaimo L, Endo Y, Lima HA, Ruzzenente A, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Cloyd J, Ejaz A, Pawlik TM. Combined Tumor Burden Score and Carbohydrate Antigen 19-9 Grading System to Predict Outcomes Among Patients with Intrahepatic Cholangiocarcinoma. J Am Coll Surg. 2023 Apr 1;236(4):804-813. doi: 10.1097/XCS.0000000000000557. Epub 2023 Jan 12. |
| Munir MM, Endo Y, Lima HA, Alaimo L, Moazzam Z, Shaikh C, Poultsides GA, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Kitago M, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Cauchy F, Koerkamp BG, Endo I, Pawlik TM. Albumin-Bilirubin Grade and Tumor Burden Score Predict Outcomes Among Patients with Intrahepatic Cholangiocarcinoma After Hepatic Resection: a Multi- Institutional Analysis. J Gastrointest Surg. 2023 Mar;27(3):544-554. doi: 10.1007/s11605-023-05578-z. Epub 2023 Jan 18. |
| Nguyen CL, Comerford AP, Dayaratna N, Lata T, Paredes SR, Easwaralingam N, Seah JL, Azimi F, Mak C, Pulitano C, Warrier SK. Trends in outcomes with adoption of indocyanine green angiography in postmastectomy reconstruction. ANZ J Surg. 2023 Jan;93(1-2):270-275. doi: 10.1111/ans.18241. Epub 2022 Dec 28. |
| Nguyen CL, Zhou M, Easwaralingam N, Seah JL, Azimi F, Mak C, Pulitano C, Warrier S. Novel Dual Tracer Indocyanine Green and Radioisotope Versus Gold Standard Sentinel Lymph Node Biopsy in Breast Cancer: The GREENORBLUE Trial. Ann Surg Oncol. 2023 Oct;30(11):6520-6527. doi: 10.1245/s10434-023-13824-6. Epub 2023 Jul 4. |
| Nguyen CL, Zhou M, Easwaralingam N, Seah JL, Azimi F, Mak C, Pulitano C, Warrier SK. ASO Author Reflections: Indocyanine Green Fluorescence Sentinel Lymph Node Biopsy in Breast Cancer-An Alternative to Blue Dye? Ann Surg Oncol. 2023 Oct;30(11):6528-6529. doi: 10.1245/s10434-023-13951-0. Epub 2023 Jul 20. |
| Risbey CWG, Pulitano C. Normothermic Ex Vivo Machine Perfusion for Liver Transplantation: A Systematic Review of Progress in Humans. J Clin Med. 2023 May 28;12(11):3718. doi: 10.3390/jcm12113718. |
| Xin H, Romanazzo S, Tomaskovic-Crook E, Mitchell TC, Hung JC, Wise SG, Cheng K, Al Maruf DSA, Stokan MJ, Manzie TGH, Parthasarathi K, Cheung VKY, Gupta R, Ly M, Pulitano C, Wise IK, Crook JM, Clark JR. Ex Vivo Preservation of Ovine Periosteum Using a Perfusion Bioreactor System. Cells. 2023 Jun 27;12(13):1724. doi: 10.3390/cells12131724. |
| Zhang XF, Xue F, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Cauchy F, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Lymph Node Examination and Patterns of Nodal Metastasis Among Patients with Left- Versus Right-Sided Intrahepatic Cholangiocarcinoma After Major Curative-Intent Resection. Ann Surg Oncol. 2023 Mar;30(3):1424-1433. doi: 10.1245/s10434-022-12797-2. Epub 2022 Nov 18. |
| Chetwood JD, Wells MG, Tsoutsman T, Pulitano C, Crawford MD, Liu K, Strasser SI, McCaughan GW, Majumdar A. MELD-GRAIL and MELD-GRAIL-Na Are Not Superior to MELD or MELD-Na in Predicting Liver Transplant Waiting List Mortality at a Single-center Level. Transplant Direct. 2022 Jun 10;8(7):e1346. doi: 10.1097/TXD.0000000000001346. |
| Dennis C, Prince DS, Moayed-Alaei L, Remash D, Carr-Boyd E, Bowen DG, Strasser SI, Crawford M, Pulitano C, Kench J, McCaughan GW, McKenzie C, Liu K. Association between vessels that encapsulate tumour clusters vascular pattern and hepatocellular carcinoma recurrence following liver transplantation. Front Oncol. 2022 Oct 26;12:997093. doi: 10.3389/fonc.2022.997093. |
| Dip F, Boni L, Bouvet M, Carus T, Diana M, Falco J, Gurtner GC, Ishizawa T, Kokudo N, Lo Menzo E, Low PS, Masia J, Muehrcke D, Papay FA, Pulitano C, Schneider-Koraith S, Sherwinter D, Spinoglio G, Stassen L, Urano Y, Vahrmeijer A, Vibert E, Warram J, Wexner SD, White K, Rosenthal RJ. Consensus Conference Statement on the General Use of Near-infrared Fluorescence Imaging and Indocyanine Green Guided Surgery: Results of a Modified Delphi Study. Ann Surg. 2022 Apr 1;275(4):685-691. doi: 10.1097/SLA.0000000000004412. |
| Franssen S, Soares KC, Jolissaint JS, Tsilimigras DI, Buettner S, Alexandrescu S, Marques H, Lamelas J, Aldrighetti L, Gamblin TC, Maithel SK, Pulitano C, Margonis GA, Weiss MJ, Bauer TW, Shen F, Poultsides GA, Marsh JW, Cercek A, Kemeny N, Kingham TP, D'Angelica M, Pawlik TM, Jarnagin WR, Koerkamp BG. Comparison of Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Patients With Multifocal Intrahepatic Cholangiocarcinoma. JAMA Surg. 2022 Jul 1;157(7):590-596. doi: 10.1001/jamasurg.2022.1298. |
| Lau NS, Ly M, Dennis C, Liu K, Kench J, Crawford M, Pulitano C. Long-term normothermic perfusion of human livers for longer than 12 days. Artif Organs. 2022 Dec;46(12):2504-2510. doi: 10.1111/aor.14372. Epub 2022 Aug 5. PMID: 35929443. |
| Lau NS, Ly M, Liu K, Majumdar A, McCaughan G, Crawford M, Pulitano C. Current and Potential Applications for Indocyanine Green in Liver Transplantation. Transplantation. 2022 Jul 1;106(7):1339-1350. doi: 10.1097/TP.0000000000004024. Epub 2021 Dec 27. |
| Lau NS, Ly M, Liu K, Majumdar A, Strasser SI, Biswas RK, McCaughan GW, Crawford M, Pulitano C. Is it safe to expand the indications for split liver transplantation in adults? A single-center analysis of 155 in-situ splits. Clin Transplant. 2022 Jul;36(7):e14673. doi: 10.1111/ctr.14673. Epub 2022 Apr 26. |
| Ly M, Lau NS, McKenzie C, Kench JG, McCaughan G, Crawford M, Pulitano C. The Delay of Arterialization After Initial Portal Reperfusion More Than Warm Ischemia Time May Determine Ischemic-type Biliary Injury. Transplantation. 2022 Feb 1;106(2):e167-e168. doi: 10.1097/TP.0000000000003936. |
| Nguyen CL, Tam SKM, Easwaralingam N, Seah JL, Comerford AP, Yu ACX, Mak C, Pulitano C, Warrier SK. Patterns of ischaemia and reperfusion in nipple-sparing mastectomy reconstruction with indocyanine green angiography. J Plast Reconstr Aesthet Surg. 2022 Nov;75(11):4144-4151. doi: 10.1016/j.bjps.2022.08.006. Epub 2022 Aug 5. |
| Salimi S, Pandya K, Davis RJ, Crawford M, Pulitano C, Strasser SI, McCaughan GW, Majumdar A, Liu K. Impact of Intensive Care Unit Discharge Delay on Liver Transplantation Outcomes. J Clin Med. 2022 May 2;11(9):2561. doi: 10.3390/jcm11092561. |
| Spolverato G, Capelli G, Lorenzoni G, Gregori D, He J, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. ASO Visual Abstract: Dynamic Prediction of Survival After Curative Resection of Intrahepatic Cholangiocarcinoma: A Landmarking-Based Analysis. Ann Surg Oncol. 2022 Nov;29(12):7644-7645. doi: 10.1245/s10434-022-12290-w. |
| Spolverato G, Capelli G, Lorenzoni G, Gregori D, He J, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Dynamic Prediction of Survival After Curative Resection of Intrahepatic Cholangiocarcinoma: A Landmarking-Based Analysis. Ann Surg Oncol. 2022 Nov;29(12):7634-7641. doi: 10.1245/s10434-022-12156-1. Epub 2022 Jul 24. |
| Tsilimigras DI, Ejaz A, Cloyd J, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM. Tumor Necrosis Impacts Prognosis of Patients Undergoing Resection for T1 Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2022 Mar 17. doi: 10.1245/s10434-022-11462-y. Epub ahead of print. |
| Wei T, Zhang XF, He J, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Prognostic impact of perineural invasion in intrahepatic cholangiocarcinoma: multicentre study. Br J Surg. 2022 Jun 14;109(7):610-616. doi: 10.1093/bjs/znac098. |
| Yu V, Ebrahimi N, Cachalia T, Jacques A, Wyburn K, McCaughan GW, Dunkley S, Crawford MD, Pulitano C, Laurence JM. Combined Liver-Kidney Transplant for Juvenile Polycystic Kidney Disease and Concomitant Hereditary Factor V Deficiency. Exp Clin Transplant. 2022 Nov;20(11):1043-1045. doi: 10.6002/ect.2022.0229. |
| Lau NS, Jacques A, McCaughan G, Crawford M, Liu K, Pulitano C. Addressing the challenges of split liver transplantation through technical advances. A systematic review. Transplant Rev (Orlando). 2021 Jul;35(3):100627. doi: 10.1016/j.trre.2021.100627. Epub 2021 May 19. PMID: 34052472. |
| Lau NS, Liu K, Almoflihi A, Xu J, McCaughan G, Crawford M, Pulitano C. Liberal Use of Interposition Grafts for Arterial Reconstruction Is Safe and Effective in Adult Split Liver Transplantation. Transplant Direct. 2021 Jul 23;7(8):e735. doi: 10.1097/TXD.0000000000001192. PMID: 34549087; PMCID: PMC8440025. |
| Lau NS, Liu K, McCaughan G, Crawford M, Pulitano C. Are split liver grafts a suitable option in high-risk liver transplant recipients? Curr Opin Organ Transplant. 2021 Dec 1;26(6):675-680. doi: 10.1097/MOT.0000000000000938. PMID: 34653087. |
| Lau NS, Ly M, Jacques A, Ewenson K, Mestrovic N, Almoflihi A, Koutalistras N, Liu K, Kench J, McCaughan G, Crawford M, Pulitano C. Prolonged Ex Vivo Normothermic Perfusion of a Split Liver: An Innovative Approach to Increase the Number of Available Grafts. Transplant Direct. 2021 Sep 7;7(10):e763. doi: 10.1097/TXD.0000000000001216. PMID: 34514118; PMCID: PMC8425846. |
| Lau NS, Ly M, Liu K, Majumdar A, McCaughan G, Crawford M, Pulitano C. Current and Potential Applications for Indocyanine Green in Liver Transplantation. Transplantation. 2021 Dec 27. doi: 10.1097/TP.0000000000004024. Epub ahead of print. PMID: 34966106. |
| Tsilimigras DI, Hyer JM, Paredes AZ, Moris D, Sahara K, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Sasaki K, Aucejo F, Zhang XF, Pawlik TM. Tumor Burden Dictates Prognosis Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma: A Tool to Guide Post-Resection Adjuvant Chemotherapy? Ann Surg Oncol. 2021 Apr;28(4):1970-1978. doi: 10.1245/s10434-020-09393-7. Epub 2020 Dec 1. PMID: 33259043. |
| Tsilimigras DI, Sahara K, Paredes AZ, Moro A, Mehta R, Moris D, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM. Predicting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma. J Gastrointest Surg. 2021 May;25(5):1156-1163. doi: 10.1007/s11605-020-04720-5. Epub 2020 Jul 14. PMID: 32757124. |
| Zhang XF, Xue F, Dong DH, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Number and Station of Lymph Node Metastasis After Curative-intent Resection of Intrahepatic Cholangiocarcinoma Impact Prognosis. Ann Surg. 2021 Dec 1;274(6):e1187-e1195. doi: 10.1097/SLA.0000000000003788. PMID: 31972643. |
| Zhang XF, Xue F, He J, Alexandrescu S, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Proposed modification of the eighth edition of the AJCC staging system for intrahepatic cholangiocarcinoma. HPB (Oxford). 2021 Sep;23(9):1456-1466. doi: 10.1016/j.hpb.2021.02.009. Epub 2021 Mar 18. PMID: 33814298. |
| Dip F, Boni L, Bouvet M, Carus T, Diana M, Falco J, Gurtner GC, Ishizawa T, Kokudo N, Lo Menzo E, Low PS, Masia J, Muehrcke D, Papay FA, Pulitano C, Schneider-Koraith S, Sherwinter D, Spinoglio G, Stassen L, Urano Y, Vahrmeijer A, Vibert E, Warram J, Wexner SD, White K, Rosenthal RJ. Consensus Conference Statement on the General Use of Near-Infrared Fluorescence Imaging and Indocyanine Green Guided Surgery: Results of a Modified Delphi Study. Ann Surg. 2020 Nov 17. doi: 10.1097/SLA.0000000000004412. Epub ahead of print. PMID: 33214476. |
| Hu LS, Zhang XF, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Redefining Conditional Overall and Disease-Free Survival After Curative Resection for Intrahepatic Cholangiocarcinoma: a Multi- institutional, International Study of 1221 patients. J Gastrointest Surg. 2020 Dec;24(12):2756-2765. doi: 10.1007/s11605-019-04472-x. Epub 2019 Dec 10. PMID: 31823320. |
| Lau NS, Jacques A, McCaughan G, Crawford M, Liu K, Pulitano C. Addressing the challenges of split liver transplantation through technical advances. A systematic review. Transplant Rev (Orlando). 2021 May 19;35(3):100627. doi: 10.1016/j.trre.2021.100627. Epub ahead of print. PMID: 34052472. |
| Moro A, Mehta R, Sahara K, Tsilimigras DI, Paredes AZ, Farooq A, Hyer JM, Endo I, Shen F, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Soubrane O, Koerkamp BG, Sasaki K, Pawlik TM. The Impact of Preoperative CA19-9 and CEA on Outcomes of Patients with Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2020 Aug;27(8):2888-2901. doi: 10.1245/s10434-020-08350-8. Epub 2020 Mar 20. PMID: 32198569. |
| Pandya K, Sastry V, Panlilio MT, Yip TCF, Salimi S, West C, Virtue S, Wells M, Crawford M, Pulitano C, Strasser SI, McCaughan GW, Majumdar A, Liu K. Differential Impact of Extended Criteria Donors After Brain Death or Circulatory Death in Adult Liver Transplantation. Liver Transpl. 2020 Dec;26(12):1603-1617. doi: 10.1002/lt.25859. Epub 2020 Sep 21. PMID: 32750732. |
| Salimi S, Pandya K, Sastry V, West C, Virtue S, Wells M, Crawford M, Pulitano C, McCaughan GW, Majumdar A, Strasser SI, Liu K. Impact of Having a Planned Additional Operation at Time of Liver Transplant on Graft and Patient Outcomes. J Clin Med. 2020 Feb 24;9(2):608. doi: 10.3390/jcm9020608. PMID: 32102393; PMCID: PMC7073734. |
| Tsilimigras DI, Hyer JM, Paredes AZ, Diaz A, Moris D, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM. A Novel Classification of Intrahepatic Cholangiocarcinoma Phenotypes Using Machine Learning Techniques: An International Multi-Institutional Analysis. Ann Surg Oncol. 2020 Dec;27(13):5224-5232. doi: 10.1245/s10434-020-08696-z. Epub 2020 Jun 3. PMID: 32495285. |
| Tsilimigras DI, Hyer JM, Paredes AZ, Moris D, Sahara K, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Sasaki K, Aucejo F, Zhang XF, Pawlik TM. Tumor Burden Dictates Prognosis Among Patients Undergoing Resection of Intrahepatic Cholangiocarcinoma: A Tool to Guide Post-Resection Adjuvant Chemotherapy? Ann Surg Oncol. 2021 Apr;28(4):1970-1978. doi: 10.1245/s10434-020-09393-7. Epub 2020 Dec 1. PMID: 33259043. |
| Tsilimigras DI, Mehta R, Aldrighetti L, Poultsides GA, Maithel SK, Martel G, Shen F, Koerkamp BG, Endo I, Pawlik TM; International Intrahepatic Cholangiocarcinoma Study Group. Development and Validation of a Laboratory Risk Score (LabScore) to Predict Outcomes after Resection for Intrahepatic Cholangiocarcinoma. J Am Coll Surg. 2020 Apr;230(4):381-391.e2. doi: 10.1016/j.jamcollsurg.2019.12.025. Epub 2020 Jan 31. PMID: 32014569. |
| Tsilimigras DI, Mehta R, Moris D, Sahara K, Bagante F, Paredes AZ, Moro A, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM. A Machine-Based Approach to Preoperatively Identify Patients with the Most and Least Benefit Associated with Resection for Intrahepatic Cholangiocarcinoma: An International Multi-institutional Analysis of 1146 Patients. Ann Surg Oncol. 2020 Apr;27(4):1110-1119. doi: 10.1245/s10434-019-08067-3. Epub 2019 Nov 14. PMID: 31728792. |
| Tsilimigras DI, Moris D, Mehta R, Paredes AZ, Sahara K, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM. The systemic immune-inflammation index predicts prognosis in intrahepatic cholangiocarcinoma: an international multi-institutional analysis. HPB (Oxford). 2020 Dec;22(12):1667-1674. doi: 10.1016/j.hpb.2020.03.011. Epub 2020 Apr 4. PMID: 32265108. |
| Tsilimigras DI, Sahara K, Moris D, Mehta R, Paredes AZ, Ratti F, Marques HP, Soubrane O, Lam V, Poultsides GA, Popescu I, Alexandrescu S, Martel G, Workneh A, Guglielmi A, Hugh T, Aldrighetti L, Weiss M, Bauer TW, Maithel SK, Pulitano C, Shen F, Koerkamp BG, Endo I, Pawlik TM. Assessing Textbook Outcomes Following Liver Surgery for Primary Liver Cancer Over a 12-Year Time Period at Major Hepatobiliary Centers. Ann Surg Oncol. 2020 Sep;27(9):3318-3327. doi: 10.1245/s10434-020-08548-w. Epub 2020 May 9. PMID: 32388742. |
| Tsilimigras DI, Sahara K, Paredes AZ, Moro A, Mehta R, Moris D, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Endo I, Pawlik TM. Predicting Lymph Node Metastasis in Intrahepatic Cholangiocarcinoma. J Gastrointest Surg. 2021 May;25(5):1156-1163. doi: 10.1007/s11605-020-04720-5. Epub 2020 Jul 14. PMID: 32757124. |
| Tsilimigras DI, Sahara K, Wu L, Moris D, Bagante F, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Moro A, Sasaki K, Aucejo F, Zhang XF, Matsuyama R, Endo I, Pawlik TM. Very Early Recurrence After Liver Resection for Intrahepatic Cholangiocarcinoma: Considering Alternative Treatment Approaches. JAMA Surg. 2020 Sep 1;155(9):823-831. doi: 10.1001/jamasurg.2020.1973. PMID: 32639548; PMCID: PMC7344787. |
| Zhang XF, Xue F, Dong DH, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Number and Station of Lymph Node Metastasis After Curative-intent Resection of Intrahepatic Cholangiocarcinoma Impact Prognosis. Ann Surg. 2020 Jan 14. doi: 10.1097/SLA.0000000000003788. Epub ahead of print. PMID: 31972643. |
| Zhang XF, Xue F, He J, Alexandrescu S, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Proposed modification of the eighth edition of the AJCC staging system for intrahepatic cholangiocarcinoma. HPB (Oxford). 2021 Mar 18:S1365-182X(21)00060-5. doi: 10.1016/j.hpb.2021.02.009. Epub ahead of print. PMID: 33814298. |
| Bagante F, Spolverato G, Merath K, Weiss M, Alexandrescu S, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Guglielmi A, Endo I, Pawlik TM. Intrahepatic cholangiocarcinoma tumor burden: A classification and regression tree model to define prognostic groups after resection. Surgery. 2019 Dec;166(6):983-990. doi: 10.1016/j.surg.2019.06.005. Epub 2019 Jul 17. |
| Buettner S, Ten Cate DWG, Bagante F, Alexandrescu S, Marques HP, Lamelas J, Aldrighetti L, Gamblin TC, Maithel SK, Pulitano C, Margonis GA, Weiss M, Bauer TW, Shen F, Poultsides GA, Marsh JW, IJzermans JNM, Pawlik TM, Koerkamp BG. Survival after Resection of Multiple Tumor Foci of Intrahepatic Cholangiocarcinoma. J Gastrointest Surg. 2019 Nov;23(11):2239-2246. doi: 10.1007/s11605-019-04184-2. Epub 2019 Mar 18. |
| D'Souza K, Crowley SP, Hameed A, Lam S, Pleass HC, Pulitano C, Laurence JM. Prophylactic Wound Drainage in Renal Transplantation: A Systematic Review. Transplant Direct. 2019 Jun 27;5(7):e468. doi: 10.1097/TXD.0000000000000908. eCollection 2019 Jul. |
| Hu LS, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Pawlik TM. Impact of microvascular invasion on clinical outcomes after curative-intent resection for intrahepatic cholangiocarcinoma. J Surg Oncol. 2019 Jan;119(1):21-29. doi: 10.1002/jso.25305. Epub 2018 Nov 22. |
| Hu LS, Zhang XF, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Lv Y, Pawlik TM. Redefining Conditional Overall and Disease-Free Survival After Curative Resection for Intrahepatic Cholangiocarcinoma: a Multi-institutional, International Study of 1221 patients. J Gastrointest Surg. 2019 Dec 10. doi: 10.1007/s11605-019-04472-x. [Epub ahead of print] |
| Hu LS, Zhang XF, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Pawlik TM. Recurrence Patterns and Timing Courses Following Curative-Intent Resection for Intrahepatic Cholangiocarcinoma. Ann Surg Oncol. 2019 Aug;26(8):2549-2557. doi: 10.1245/s10434-019-07353-4. Epub 2019 Apr 24. |
| Merath K, Chen Q, Bagante F, Alexandrescu S, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Weiss MJ, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Guglielmi A, Itaru E, Cloyd JM, Pawlik TM. A Multi-institutional International Analysis of Textbook Outcomes Among Patients Undergoing Curative-Intent Resection of Intrahepatic Cholangiocarcinoma. JAMA Surg. 2019 Jun 1;154(6):e190571. doi: 10.1001/jamasurg.2019.0571. Epub 2019 Jun 19. |
| Merath K, Mehta R, Hyer JM, Bagante F, Sahara K, Alexandrescu S, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Weiss MJ, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Guglielmi A, Itaru E, Ejaz A, Pawlik TM. Impact of body mass index on tumor recurrence among patients undergoing curative-intent resection of intrahepatic cholangiocarcinoma- a multi-institutional international analysis. Eur J Surg Oncol. 2019 Jun;45(6):1084-1091. doi: 10.1016/j.ejso.2019.03.004. Epub 2019 Mar 7. |
| Morris PD, Furtado R, Pulitano C, Crawford M, Yeo D, Vasilaras A, Sandroussi C. Inferior Vena Cava Resection and Reconstruction with Bovine Pericardium for Renal Cell Carcinoma: Complications and Outcomes. Urology. 2019 Dec;134:143-147. doi: 10.1016/j.urology.2019.09.006. Epub 2019 Sep 19. |
| Sahara K, Tsilimigras DI, Merath K, Bagante F, Guglielmi A, Aldrighetti L, Weiss M, Bauer TW, Alexandrescu S, Poultsides GA, Maithel SK, Marques HP, Martel G, Pulitano C, Shen F, Soubrane O, Koerkamp BG, Matsuyama R, Endo I, Pawlik TM. Therapeutic Index Associated with Lymphadenectomy Among Patients with Intrahepatic Cholangiocarcinoma: Which Patients Benefit the Most from Nodal Evaluation? Ann Surg Oncol. 2019 Sep;26(9):2959-2968. doi: 10.1245/s10434-019-07483-9. Epub 2019 May 31. |
| Zhang XF, Lv Y, Weiss M, Popescu I, Marques HP, Aldrighetti L, Maithel SK, Pulitano C, Bauer TW, Shen F, Poultsides GA, Soubrane O, Martel G, Koerkamp BG, Itaru E, Pawlik TM. Should Utilization of Lymphadenectomy Vary According to Morphologic Subtype of Intrahepatic Cholangiocarcinoma? Ann Surg Oncol. 2019 Jul;26(7):2242-2250. doi: 10.1245/s10434-019-07336-5. Epub 2019 Mar 29. |