Tissue Pathology and Diagnostic Oncology at RPA has a broad-based research program encompassing basic, translational and clinical studies in a wide range of organs, including skin, head and neck, lung, breast, colorectum, prostate, liver and pancreas. 

The melanoma group studies causes, diagnosis, prognostication and treatment in one of Australia's most common malignancies and are recognised international leaders in this field. The head and neck, lung, prostate and breast groups have established national and international profiles in pathology research focusing on diagnosis and prediction of behaviour in these tumours, as well as developing predictive markers for targeted therapy.