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Sydney Melanoma Diagnostic Centre Research

Our Research Team

Professor Pascale Guitera Dermatologist
Director, Sydney Melanoma Diagnostic Centre
Clinical Academic, University of Sydney
Dr Amanda Regio Pereira Dermatologist and PhD Candidate
Dr Bruna Gallo Dermatology Research Assistant and Masters Student
Milapatabeige (Sampi) Kulasekara Clinical Imaging and Research Assistant
Bruna Gouvia PhD Candidate
Arthur Martin Masters Student

Selected Grants

Amount awarded Grant and project details
$10,000,000 Australian Cancer Research Fund, 2019-2023
Australian Centre of Excellence in Melanoma Imaging and Diagnosis
Investigators: Soyer HP, Mann G, Mar V, Janda M, Aitken J, Fernandez-Penas P, Gray L, Menzies SW, Scolyer R, Wolfe R, Cust A, Guitera P, McCormack C, Morton R, Caffery L.
$5,276,225 Innovation Fund Denmark, 2019-2024
AI augmented training in Skin Cancer diagnostics 
Investigators: Guitera P, et al.
$2,400,000 MRFF Targeted Health System and Community Organisation Research Grant, 2019-2022
Melanoma surveillance photography to improve early detection of melanoma in very high risk (or high risk) patients
Investigators: Mar V, Guitera P, et al.
$1,229,189 NHMRC Project Grant, 2018-2022
Can patient-led surveillance detect recurrent or new primary melanoma & reduce need for routinely scheduled follow-up? A Randomised Controlled Trial
Investigators: Bell C, Janda M, Cust A, Turner R, Irwig L, Guitera P, Saw R, Mar V,  Dieng M, Hersch J.
$839,351 NHMRC Project Grant, 2018-2022
A national risk-stratified melanoma screening program in Australia: a modelling study of the benefits, harms, cost-effectiveness and resource implications
Investigators: Cust A, Canfell K, Aitken J, Guitera P, Aranda S, Watts C, Rankin N, Fernandez-Penas P.

Our Publications

2022

Professor Pascale Guitera

Byers C, Gill M, Kurtansky NR, Alessi-Fox C, Harman M, Cordova M, Gonzalez S, Guitera P, Rotemberg V, Marghoob A, Chen CJ, Dy J, Kose K, Rajadhyaksha M, Sahu A. Tertiary lymphoid structures accompanied by fibrillary matrix morphology impact anti-tumor immunity in basal cell carcinomas. Front Med (Lausanne). 2022 Oct 27;9:981074. doi: 10.3389/fmed.2022.981074. PMID: 36388913; PMCID: PMC9647637.
Caffery LJ, Janda M, Miller R, Abbott LM, Arnold C, Caccetta T, Guitera P, Shumack S, Fernández-Peñas P, Mar V, Soyer HP. Informing a position statement on the use of artificial intelligence in dermatology in Australia. Australas J Dermatol. 2022 Nov 15. doi: 10.1111/ajd.13946. Epub ahead of print. PMID: 36380357.
Fuchs CSK, Ortner VK, Mogensen M, Rossi AM, Pellacani G, Welzel J, Mosterd K, Guitera P, Nayahangan LJ, Johnsson VL, Haedersdal M, Tolsgaard MG; OCT-BCC expert panel. 2021 international consensus statement on optical coherence tomography for basal cell carcinoma: image characteristics, terminology and educational needs. J Eur Acad Dermatol Venereol. 2022 Jun; 36(6):772-778.
Gaetano L, Domenico B, Lo SN, Hamed T, Potter AJ, Thompson JF, Scolyer RA, Guitera P. Association between excision margins and local recurrence in 1407 patients with primary in situ melanomas. JAAD Int. 2022 Jun 16;8:102-108. doi: 10.1016/j.jdin.2022.06.001. PMID: 35875393; PMCID: PMC9305371.
Guitera P, Waddell A, Paton E, Fogarty GB, Hong A, Scolyer RA, Stretch JR, O'Donnell BA, Pellacani G. Re: Reply to letter to the editor re: 'practical guide on the use of imiquimod cream to treat lentigo maligna'. Australas J Dermatol. 2022 May;63(2):e198-e199.
Ho G, Schwartz RJ, Melhoranse-Gouveia B, Guitera P, O'Sullivan NA, Cheung VKY, Ch'ng S, Martin LK. Utility of optical coherence tomography in basal cell naevus syndrome: A case report. Australas J Dermatol. 2022 Sep 20. doi: 10.1111/ajd.13921. Epub ahead of print. PMID: 36125195.
Ho G, Schwartz RJ, Regio Pereira A, Dimitrou F, Paver E, McKenzie C, Saw RPM, Scolyer RA, Long GV, Guitera P. Reflectance confocal microscopy - a non-invasive tool for monitoring systemic treatment response in stage III unresectable primary scalp melanoma. J Eur Acad Dermatol Venereol. 2022 Mar 14. doi: 10.1111/jdv.18076.
Ho G, Smith A, Cust AE, Melhoranse-Gouveia B, Collgros H, Martin L, Guitera P. Reflectance confocal microscopy in Australia: Perspectives on barriers to implementation and uptake. Australas J Dermatol. 2022 Nov 22. doi: 10.1111/ajd.13954. Epub ahead of print. PMID: 36412240.
Martin A, Gouveia BM, Rawson R, Guitera P. Complex management of lentigo maligna in the setting of chrysiasis, argyriasis, and tattoo using in vivo reflectance confocal microscopy. J Dermatol. 2022 May 5. doi: 10.1111/1346-8138.16390. Epub ahead of print. PMID: 35514028.
Pennington TE, Zhao CY, Colebatch AJ, Fernandez-Peñas P, Guitera P, Burke H, Scolyer RA, Menzies AM, Carlino MS, Lo S, Long GV, Saw RP. Clinicopathological characteristics of new primary melanomas in patients receiving immune checkpoint inhibitor therapy for metastatic melanoma. Australas J Dermatol. 63(2):e133-e137
Pereira AR, Corral-Forteza M, Collgros H, El Sharouni MA, Ferguson PM, Scolyer RA, Guitera P. Dermoscopic features and screening strategies for the detection of small-diameter melanomas. Clin Exp Dermatol. 2022 Jan 7. doi: 10.1111/ced.15094.
Pham F, Boespflug A, Duru G, Phan A, Poulalhon N, Weiler L, Tanaka M, Lallas A, Ogata D, Davaine AC, Bahadoran P, Balguerie X, Kamińska-Winciorek G, Tromme I, Correia O, Kim MB, Marghoob AA, Martin L, Guitera P, Meziane M, Miquel J, Mun JH, Argenziano G, Bessis D, Bourke J, Mijuskovic Z, Chiaverini C, Corven-Benoit C, Droitcourt C, Skowron F, Marque M, Zalaudek I, Rosendahl C, Moreno-Ramirez D, Vabres P, Haenssle H, Malvehy J, Puig S, Robert C, Schopf TR, Scope A, Dalle S, Thomas L. "Dermoscopic and clinical features of congenital or congenital-type nail matrix nevi: a multicenter prospective cohort study by the International Dermoscopy Society". J Am Acad Dermatol. 2022 Jan 29:S0190-9622(22)00158-X.
Sahu A, Kose K, Kraehenbuehl L, Byers C, Holland A, Tembo T, Santella A, Alfonso A, Li M, Cordova M, Gill M, Fox C, Gonzalez S, Kumar P, Wang AW, Kurtansky N, Chandrani P, Yin S, Mehta P, Navarrete-Dechent C, Peterson G, King K, Dusza S, Yang N, Liu S, Phillips W, Guitera P, Rossi A, Halpern A, Deng L, Pulitzer M, Marghoob A, Chen CJ, Merghoub T, Rajadhyaksha M. In vivo tumor immune microenvironment phenotypes correlate with inflammation and vasculature to predict immunotherapy response. Nat Commun. 2022 Sep 9;13(1):5312. doi: 10.1038/s41467-022-32738-7. PMID: 36085288; PMCID: PMC9463451.
Schwartz RJ, Ho G, Gouveia BM, Martin LK, Guitera P. An adapter window for precise skin marking during handheld reflectance confocal microscopy scanning. J Am Acad Dermatol. 2022 Jan 24:S0190-9622(22)00097-4. doi: 10.1016/j.jaad.2021.11.064.
Thompson JR, Smith AL, Lo SN, Kasparian NA, Saw RP, Dieng M, Seaman L, Martin LK, Guitera P, Milne D, Schmid H, Cust AE, Bartula I. Protocol for the implementation of a stepped-care model to address fear of cancer recurrence in patients previously diagnosed with early-stage (0-II) melanoma. BMJ Open. 2022 Mar 3;12(3):e054337

Dr Amanda Regio Pereira

Ho G, Schwartz RJ, Regio Pereira A, Dimitrou F, Paver E, McKenzie C, Saw RPM, Scolyer RA, Long GV, Guitera P. Reflectance confocal microscopy - a non-invasive tool for monitoring systemic treatment response in stage III unresectable primary scalp melanoma. Journal of the European Academy of Dermatology and Venereology. 2022 Mar 14. Epub ahead of print.
Pereira AR*, Corral-Forteza M*, Collgros H, El Sharouni MA, Ferguson PM, Scolyer RA, Guitera P. Dermoscopic features and screening strategies for the detection of small-diameter melanomas. Clinical and Experimental Dermatology. 2022 Jan 7. *Shared co-first authorship.
Schwartz RJ, Ho G, Smith A, Collgros H, Regio Pereira A, Gouveia B, Long GV, Menzies AM, Potter AJ, Paver E, Star P, Scolyer RA, Martin LK. Successful treatment of eruptive keratoacanthomas with acitretin for patients on checkpoint inhibitor immunotherapy. Journal of the European Academy of Dermatology and Venereology. 2022 Jan 18. Epub ahead of print.