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Surgical Outcomes Research Centre (SOuRCe)

The Surgical Outcomes Research Centre (SOuRCe) was establishment in 2002 and has aimed to promote an evidence-based approach to improve clinical practice and achieve the best possible outcome for patients. As a multidisciplinary, academic research unit of Sydney Local Health District and the University of Sydney; our research agenda addresses diverse aspects of surgical outcomes, including surgical effectiveness, patient reported outcomes and quality of life, patterns of care and evidence-based practice, health economic evaluation, assessment of patient preferences, surgical decision-making and other methodological studies. 

Overall Research Output
Currently, SOuRCe is involved in 173 research studies in collaboration with multi-specialty surgical departments, allied health, nursing, other academics and consumers, based in Australia and Internationally. Over 55% of our research studies are registry-nested and originate from comprehensive data collected from the funded surgical programs, including the Advanced Gastrointestinal Research Program, Robotics Program, Orthopaedic Surgery and Vascular Surgery Programs. The other 45% of our research originates from historical collaborations within the following departments: colorectal, transplant, urology, ear, nose and throat, orthopaedics, upper gastrointestinal, breast, vascular, allied health, head and neck, anaesthetics, nursing, benign gynaecology, pathology, imaging, pharmacy and other departments and institutions.

Over the past 20 years, SOuRCe has rapidly developed to become one of the major Australian surgical research units, and is now a centre of surgical research excellence with international recognition. During this time, SOuRCe was awarded over $20M in competitive funding, including major funding bodies such as the NHMRC, MRFF, CINSW, NIHR and others. SOuRCe has published over 500 peer-reviewed scientific articles in the top surgical and medical journals, including NATURE, BMJ, JAMA surgery, Annals of Surgery, The British Journal of Surgery, Journal of Surgical Oncology and other high impact journals. SOuRCe has supervised over 70 PhD and MPHIL students and over 60 MD students. These achievements have contributed significantly to the enhancement of patient outcomes and have changed clinical practice at RPA, Australia and Internationally.

Funded Research Programs
Our funded surgical research programs include the Advanced Gastrointestinal Surgical Program (including Pelvic Exenteration, Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy, Retroperitoneal Sarcoma and Advanced Upper Gastrointestinal Surgery), Robotics Program, Orthopaedic Surgery, Vascular Surgery, and the Preoperative Optimisation Research Program. Most of the funded research programs are governed by the RPA Institute of Academic Surgery and are led by a large amount of multidisciplinary and multispecialty groups of clinical and non-clinical staff from a variety of departments across RPA.

Highlights of Surgical Research

Pelvic Exenteration Research Program
Pelvic exenteration is complex, radical surgery for advanced or recurrent pelvic cancers. The Royal Prince Alfred Hospital is one of the few hospitals in Australia that performs large numbers of this surgery and has evolved over 25 years into an internationally recognised centre of excellence.

Currently, SOuRCe holds the largest database in the world capturing clinical and patient reported outcomes of all pelvic exenterations performed at the Royal Prince Alfred Hospital. With over 50 ongoing research projects, the Pelvic Exenteration Research Program has extensively contributed to the development of the current clinical practice worldwide. Under the leadership of Prof Michael Solomon, the Pelvic Exenteration Program is celebrating the completion of the 1000th pelvic exenteration in 2022. This is a remarkable milestone for the program and is credited to the large group of multidisciplinary staff involved in the delivery of the Pelvic Exenteration Surgical Program. 

Peritonectomy Research Program
The Peritonectomy program at the Royal Prince Alfred Hospital is the newest addition to SOuRCe's research profile, with Cytoreductive Surgery & Hyperthermic Intraperitoneal Chemotherapy (CRS & HIPEC), performed to treat advanced cancers involving the lining of the abdomen. 

The research program started at the beginning of 2017 and undertakes detailed analysis toward better understanding the clinical outcomes, patient reported outcomes, safety benefits and cost effectiveness of this highly specialised procedure. The data collected by SOuRCe is also used to identify specific patient groups who are more likely to benefit from this highly specialised surgery. To date, more than 300 procedures have been performed at the Royal Prince Alfred Hospital, with most patients being followed up to 5-years, including measures of quality of life and health service utilisation. The comprehensive data collection is currently contributing to over 30 research projects, including major clinical trials and international collaborations.

Robotic Research Program
In late 2015, Sydney Local Health District (SLHD) announced the purchase of a da Vinci Xi Surgical Robot and a Stryker Mako Orthopaedic Surgical Robot for use in the Royal Prince Alfred Hospital and Institute of Rheumatology and Orthopaedics operating theatres. RPAH is one of the first public tertiary referral hospitals in Australia to have this state-of-the-art technology available. The following surgical specialties are currently utilising the da Vini Xi system: Cardiothoracic, Colorectal, Urology, Upper Gastrointestinal and Benign Gynaecology. 

Currently, over 500 procedures have been performed using the da Vinci robot and 400 using the Mako robotic system. The unique research framework within the Robotic Research Program at the Royal Prince Alfred Hospital, allow the collection of clinical and quality of life measures for all robotic cases. This approach resulted in the development of more than 40 research projects across multi disciplines.

Our Research Team

Our Directors

 
Professor Michael Solomon Director and Head of the Surgical Outcomes Research Centre (SOuRCe);
Academic Head and Surgeon, Department of Colorectal Surgery, Royal Prince Alfred Hospital;
Co-Chairman, RPA Institute of Academic Surgery (IAS);
Professor of Surgical Research, University of Sydney.
Dr Kate McBride Director of the Surgical Outcomes Research Centre (SOuRCe);
Executive Director of the RPA Institute of Academic Surgery.
Associate Professor Daniel Steffens
 
Director of the Surgical Outcomes Research Centre (SOuRCe). 

Our Expert Advisors

 
Professor Jane Young Executive Director, SOuRCe;
Executive Director of Research at the RPA Institute of Academic Surgery;
Professor in Cancer Epidemiology, School of Public Health, University of Sydney.
Associate Professor Charbel Sandroussi Co-Director, SOuRCe;
Director of Clinical Research at the RPA Institute of Academic Surgery;
Head of Department of Hepatobiliary and Upper Gastrointestinal Surgery, Royal Prince Alfred Hospital.
Associate Professor Cherry Koh Co-Director, SOuRCe;
Associate Professor of Surgical Outcomes, University of Sydney;
Research Lead for Colorectal Surgery at the RPA Institute of Academic Surgery.
Dr David Yeo Co-Director, SOuRCe; 
Upper Gastrointestinal, Hepatobiliary and Transplant Surgeon, Royal Prince Alfred Hospital. 
Dr Sharon Carey Co-Director, SOuRCe; 
Nutrition and Dietetics, Royal Prince Alfred Hospital.
Professor Ian Harris Co-Director, SOuRCe; 
Orthopaedic Surgeon;
Honorary Professor, School of Public Health, Faculty of Medicine & Health, University of Sydney.

Our Research Staff

 
Sascha Karunaratne Research Manager
Kate Alexander Research Manager
Madhu Prasad Administrative Officer
Jacob Bird Robotic Surgery Research Officer
James Morkaya Upper Gastrointestinal Research Officer
Henna Solanki Peritonectomy Research Officer
Kiera Taylor Pelvic Exenteration Research Officer
Lylee Ye Retroperitoneal Saracoma Research Officer
Ruby Cole Priority Trial Coordinator
Helena Lamberth Orthopaedic Research Officer
Philip Hay iCAD Trial Coordinator, Orthopaedic Research Officer
Cherie Fischer Bone and Soft Tissue Sarcoma Research Officer
Darya Shapilsky Bone and Soft Tissue Sarcoma Data Assistant

Selected Grants

Amount awarded Grant and project details
$1,119,877 NHMRC, 2020-2023
PRIORITY TRIAL - Preoperative exercise for patients undergoing major abdominal cancer surgery: A Multicentre Randomised Controlled Trial
Investigators: Young J, Solomon MJ, Riedel B, Steffens D, Morton R, Denehy L, Heriot A, Koh C, Li Q, Bauman A
$998,609 MRFF 2021 Rare Cancers, Rare Diseases and Unmet Need, 2021-2024
INTER-EWING-1 International clinical research program to improve outcomes in newly diagnosed Ewing Sarcoma patients Trial 1.
Investigators: McCowage G, Desai J, Phillips M, Ryan J, Hong A, Lewin J, Kirby M, Brennan B, Strong T, Stalley P.
$170,000 ANZSA Clinical Research Fellowship, The Kid’s Cancer Project and Rainbows For Kate Foundation, 2022-2024
ANZSA Clinical Research Fellowship
Investigator: Strach M.
US$50,000 Intuitive, 2022
UDIVERT: A randomised study assessing intracorporeal versus extracorporeal urinary diversion for patients undergoing robotic assisted radical cystectomy (RARC).
Investigators: Leslie S, Thanigasalam R, Broe M.
$41,600 University of Sydney DVCR COVID Support Scheme Grant, 2022
PRIORITY TRIAL - Preoperative exercise for patients undergoing major abdominal cancer surgery: A Multicentre Randomised controlled Trial. 
Investigators: Young J, Solomon MJ, Riedel B, Steffens D, Morton R, Denehy L, Heriot A, Koh C, Li Q, Bauman A.
$10,000 Royal Australasian College of Surgeons, 2021-2023
Hugh Johnston Travel Grant
Investigator: Coker D.

Our Publications

2022

Aitchison L, Chen A, Toms C, Sandroussi C, Yeo D, Steffens D. To Stitch or Not to Stitch: The Closure of Laparoscopic Port Sites, A Meta Analysis. Surgical Endoscopy.  2022; DOI: 10.1007/s00464-022-09269-9
Aitchison L.P., Chen A.Z.L., Toms C., Sandroussi C., Yeo D.A., Steffens D.  To stitch or not to stitch: the skin closure of laparoscopic port sites, a meta-analysis 2022,7140:7159-36.
Amaratunga H, Bostock K, Cunich M, Steffens D, Carey S. Systematic review of service-improvements for home enteral tube feeding in adults. Nutrition in Clinical Practice. 2022; https://doi.org/10.1002/ncp.10900
Arulampalam J, Bucknill A, Gupta S, Li Q, McMahon SJ. Validation of a Prototype Augmented Reality Navigation System for Total Hip Replacement. Surg Technol Int. 2022 Oct 17
Bae S, Brnabic A, Crowe P, Carey-Smith R, Andelkovic V, Singhal N, Stalley P, Yip D, Desai J. Managing patients with advanced soft tissue sarcoma: Evolving landscape from an Australian perspective. Asia Pac J Clin Oncol. 2022 Jan 30.
Bhadbhade M., Connolly E., Badiani S., Yeo D., Bhadri V.  Metastatic osteosarcoma bowel perforation secondary to chemotherapy-induced tumour necrosis 2022,:-15.
Broekhuis D, Boyle R, Karunaratne S, Chua A, Stalley P. Custom designed and 3D-printed titanium pelvic implants for acetabular reconstruction after tumour resection. Hip Int. 2022 Nov 21:11207000221135068.
Burgess A, Van Diggele C, Schneider C, Haq I, Leadbeatter D, Karunaratne S, McKenzie S, Clark T, Henry J, Bloomfield J. An Interprofessional Peer Teacher Training program for health professional students: 'face to face' versus 'online only'. Journal of University Teaching & Learning Practice 2022 (Accepted 28/10/2022)
Chang KH, Solomon MJ. The role of surgery in the palliation of advanced pelvic malignancy. European Journal of Surgical Oncology 2022; 48:2323-2329: 10.1016/j.ejso.2022.01.019
Chetwood JD, Volovets A, Sivam S, Koh C. Surgical considerations in cystic fibrosis: what every general surgeon needs to know. ANZ Journal of Surgery 2022; 92:2425-2432
Clark D, Edmundson A, Steffens D, Harris C, Stevenson A, Solomon M. Drain fluid amylase as a biomarker for the detection of anastomotic leakage after rectal resection without a diverting ileostomy. ANZ Journal of Surgery.  2022; 92:813-818. doi: 10.1111/ans.17461.
Clark DA, Edmundson A, Steffens D, Radford-Smith G, Solomon S. Multi-center study of drain fluid amylase as a biomarker for the detection of anastomotic leakage after ileal pouch surgery without a diverting ileostomy. Diseases of the Colon and Rectum. 2022; DOI:10.1097/DCR.0000000000002376
Clark DA, Stevenson A, Lumley J, Peterson D, Harris C, Steffens D, Solomon M. Does an ileostomy cover the surgeon or the anastomosis? (Perspective) ANZ Journal of Surgery 2022; 92:19-20
Clark DA, Yeoh E, Edmundson A, Harris C, Stevenson A, Steffens D, Solomon M. A Development Study of Drain Fluid Gastrografin as a Biomarker of Anastomotic Leak. Annals of coloproctology 2022; 38(2):124-132; DOI: 10.3393/ac.2020.12.24
CRISTAL Study Group. Effect of Aspirin vs Enoxaparin on Symptomatic Venous Thromboembolism in Patients Undergoing Hip or Knee Arthroplasty: The CRISTAL Randomized Trial. JAMA. 2022;328(8):719-727.
Devitt BM, Neri T, Fritsch BA. Combined Anterolateral Complex and Anterior Cruciate Ligament Injury: Anatomy, Biomechanics and Management - State-of-the-art. J ISAKOS. 2022 Nov 8:S2059-7754(22)00097-9.
Dreyer S.B., Upstill-Goddard R., Legrini A., Biankin A.V., Allison S., Beraldi D., Cameron E., Chang D.K., Cooke S.L., Cunningham R., Grimwood P., Kelly S., Marshall J., McDade B., Musgrove E.A., Ramsay D., Evers L., Rebus S., Rahib L., Serrels B., Jamieson N.B., McKay C.J., Westwood P., Williams N., Duthie F., Shen W., Pea A., Johns A.L., Gill A.J., Chantrill L.A., Timpson P., Chou A., Pajic M., Dwarte T., Herrmann D., Vennin C., Cox T.R., Pereira B., Ritchiee S., Reed D.A., Chambers C.R., Metcalf X., Nobis M., Jeong G., Kenyon L., Lyons R.J., Waddell N., Pearson J.V., Patch A.-M., Nones K., Newell F., Mukhopadhyay P., Addala V., Kazakoff S., Holmes O., Leonard C., Wood S., Grimmond S.M., Hofmann O., Samra J.S., Pavlakis N., Arena J., High H.A., Asghari R., Merrett N.D., Das A., Cosman P.H., Ismail K., Stoita A., Williams D., Spigellman A., McLeod D., Kirk J., Kench J.G., Grimison P., Sandroussi C., Goodwin A., Mead R.S., Tucker K., Andrews L., Texler M., Forrest C., Ballal M., Fletcher D., Beilin M., Feeney K., Epari K., Mukhedkar S., Zeps N., Nguyen N.Q., Ruszkiewicz A.R., Worthley C., Chen J., Brooke-Smith M.E., Papangelis V., Clouston A.D., Barbour A.P., O'Rourke T.J., Fawcett J.W., Slater K., Hatzifotis M., Hodgkinson P., Nikfarjam M., Eshleman J.R., Hruban R.H., Wolfgang C.L., Scarpa A., Lawlor R.T., Corbo V., Bassi C.  Genomic and Molecular Analyses Identify Molecular Subtypes of Pancreatic Cancer Recurrence 2022,320:3240000-162.
Fernando ME, Horsley M, Jones S, Martin B, Nube VL, Charles J, Cheney J, Lazzarini PA; Australian Diabetes-related Foot Disease Guidelines & Pathways Project. Australian guideline on offloading treatment for foot ulcers: part of the 2021 Australian evidence-based guidelines for diabetes-related foot disease. J Foot Ankle Res. 2022 May 5;15(1):31.
Figueroa F, Figueroa D, Guiloff R, Putnis S, Fritsch B, Itriago M. Navigation in anterior cruciate ligament reconstruction: state of the art. J ISAKOS. 2022 Sep 27:S2059-7754(22)00086-4.
Fitzsimmons T, Thomas M, Tonkin D, Murphy E, Hollington P, Solomon M, Sammour T, Luck A.   Establishing a State-wide Pelvic Exenteration Multidisciplinary Team Meeting in South Australia. ANZ Journal of Surgery 2022; DOI: 10.1111/ans.18220
Franssen S., Soares K.C., Jolissaint J.S., Tsilimigras D.I., Buettner S., Alexandrescu S., Marques H., Lamelas J., Aldrighetti L., Gamblin T.C., Maithel S.K., Pulitano C., Margonis G.A., Weiss M.J., Bauer T.W., Shen F., Poultsides G.A., Marsh J.W., Cercek A., Kemeny N., Kingham T.P., D'Angelica M., Pawlik T.M., Jarnagin W.R., Koerkamp B.G.  Comparison of Hepatic Arterial Infusion Pump Chemotherapy vs Resection for Patients With Multifocal Intrahepatic Cholangiocarcinoma 2022,590:596-157.
Garret C, Steffens D, Solomon M, Koh C. Early-onset colorectal cancer: why it should be high on our list of differentials. ANZ Journal of Surgery.  2022; 92:1638-1643
Harji D, Koh C, McKigney M, Solomon MJ, Griffiths B, Evan M, Heriot A, Sargar PM, Velikova G, Brown JM. Short term outcomes of Health-Related Quality of Life in Patients with Locally Recurrent Rectal Cancer: a multi-centre, international, cross-sectional cohort study. British Journal of Surgery 2022; DOI: 10.1093/bjsopen/zrac168
Hogan S, Reece L, Solomon M, R A, Carey S. Early enteral feeding is beneficial for patients after pelvic exenteration surgery - A randomised controlled trial. Journal of Parenteral and Enteral Nutrition 2022; 46(2):411-421: DOI: 10.1002/jpen.2120
Hogan S, Steffens D, Vuong K, Rangan A, Solomon M, Carey S.  Preoperative nutritional status impacts clinical outcome and hospital length of stay in pelvic exenteration patients - a retrospective study. Nutrition and Health 2022; 28(1):41-48; DOI: 10.1177/02601060211009067
Huang Y, Steffens D, Koh CE, Young JM, Solomon MJ. Differences in Surgical Outcomes and Quality of Life outcomes in Pelvic Exenteration Between Locally Advanced versus Locally Recurrent Rectal Cancer. Diseases of the Colon & Rectum 2022; 65: 1475-1482
Huang Y, Wang X, Steffens D, Young JM, Solomon MJ, Koh CE.  Grading Complications in Pelvic Exenteration: Limitations of Current Classification Systems.  Diseases of the Colon & Rectum 2022; doi: 10.1097/DCR.0000000000002396
Hulme K.R., Robbins E., Crawford M., Mahar A., McKenzie C.A.  Giant porta hepatis schwannoma: a rare cause of a cystic hepatic neoplasm 2022,140:143-54.
Ip E., McNeil C., Grimison P., Scheinberg T., Tudini E., Ho G., Scott R.J., Brown C., Sandroussi C., Guitera P., Spurdle A.B., Goodwin A.  Catastrophic chemotherapy toxicity leading to diagnosis of Fanconi anaemia due to FANCD1/BRCA2 during adulthood: description of an emerging phenotype 2022,912:915-59.
Johnstone C, Roberts D, Mathieson S, Steffens D, Koh C, Solomon M, McLachlan A, Pain, pain management and related outcomes following pelvic exenteration surgery: A systematic review. Colorectal Disease 2022; DOI: 10.1111/codi.16462
Johnstone J, Koh C, Britton GJ, Solomon MJ, McLachlan A. Implementation of a perioperative pain management algorithm reduces the use of opioid analgesia following pelvic exenteration surgery. Colorectal Disease 2022; Dec 2: DOI: 10.1111/codi.16442
Keane CR, O'Grady G, Bissett IP, Hayes J, Hulme-Moir M, Eglinton TW, Solomon MJ, Lumley JW, Simes J, Stevenson ARL.  Functional Outcome of Laparoscopic Assisted Resection vs Open Resection of Rectal Cancer: A secondary analysis of the Australasian Laparoscopic Cancer of the Rectum Trial (ALaCaRT). Diseases of the Colon & Rectum 2022; 65(7): e698-e706 DOI: 10.1097/DCR.0000000000002166
Khaw CW, Ebrahimi N, Lee P, McCarthy ASE, Solomon M.  Long‐term results of mesh pelvic floor reconstruction to address the empty pelvis syndrome. Colorectal Disease 2022; 24:1211-1215
Kibbi N, Owen JL, Worley B, Wang JX, Harikumar V, Downing MB, Aasi SZ, Aung PP, Barker CA, Bolotin D, Bordeaux JS, Cartee TV, Chandra S, Nancy L. Cho NL, Choi JN, Chung KY, Cliby WA, Dorigo O, Eisen DB, Fujisawa Y, Golda N, Halfdanarson TR, Iavazzo C, Jiang SIB,  Kanitakis J, Khan A, Kim JYS, Kuzel TM, Lawrence N, Leitao Jr MM, MD; MacLean AB, Maher IA, Mittal BB, Nehal KS, MD; Ozog DM, MD; Pettaway CA, Ross JS, Rossi AM, Servaes S,  Solomon MJ, Thomas VD, Tolia M, Voelzke BB, Waldman A, Wong MK, Zhou Y, Arai N, Brackett A, Ibrahim SA, Kang BY, Poon E, Alam M. Evidence-Based Clinical Practice Guidelines for Extramammary Paget Disease. (Clinical Review) JAMA Oncology 2022; 8:618-628
Kim RG, An VVG, Lee SLK, Khadra SM, Petchell JF. Overlapping surgery in arthroplasty - a systematic review and meta-analysis. Orthop Traumatol Surg Res. 2022 Apr 25:103299.
Kim RG, An VVG, Petchell JF. Fibular fixation in mid and distal extra-articular tibia fractures - A systematic review and meta-analysis. Foot Ankle Surg. 2022 Oct;28(7):809-816.
Koh CE, Brown KGM, Steffens D, Young J, Salkeld G, Solomon MJ. What constitutes a clear margin in patients with locally recurrent rectal cancer undergoing pelvic exenteration? Annals of Surgery 2022; 275(1):157-165: 10.1097/SLA.0000000000003834
Koh CE. Resecting the primary in unresectable stage IV colorectal cancer: Should we or shouldn't we? (Editorial). Colorectal Disease 2022; 24:809-810
Koh CE. The long road to gender equity in surgery. British Journal of Surgery. 2022; 378:o2263; DOI: 10.1136/bmj.o2263
Korenblik R., Olij B., Aldrighetti L.A., Hilal M.A., Ahle M., Arslan B., van Baardewijk L.J., Baclija I., Bent C., Bertrand C.L., Björnsson B., de Boer M.T., de Boer S.W., Bokkers R.P.H., Rinkes I.H.M.B., Breitenstein S., Bruijnen R.C.G., Bruners P., Büchler M.W., Camacho J.C., Cappelli A., Carling U., Chan B.K.Y., Chang D.H., choi J., Font J.C., Crawford M., Croagh D., Cugat E., Davis R., De Boo D.W., De Cobelli F., De Wispelaere J.F., van Delden O.M., Delle M., Detry O., Díaz-Nieto R., Dili A., Erdmann J.I., Fisher O., Fondevila C., Fretland Å., Borobia F.G., Gelabert A., Gérard L., Giuliante F., Gobardhan P.D., Gómez F., Grünberger T., Grünhagen D.J., Guitart J., Hagendoorn J., Heil J., Heise D., Herrero E., Hess G.F., Hoffmann M.H., Iezzi R., Imani F., Nguyen J., Jovine E., Kalff J.C., Kazemier G., Kingham T.P., Kleeff J., Kollmar O., Leclercq W.K.G., Ben S.L., Lucidi V., MacDonald A., Madoff D.C., Manekeller S., Martel G., Mehrabi A., Mehrzad H., Meijerink M.R., Menon K., Metrakos P., Meyer C., Moelker A., Modi S., Montanari N., Navines J., Neumann U.P., Peddu P., Primrose J.N., Qu X., Raptis D., Ratti F., Ridouani F., Rogan C., Ronellenfitsch U., Ryan S., Sallemi C., Moragues J.S., Sandström P., Sarriá L., Schnitzbauer A., Serenari M., Serrablo A., Smits M.L.J., Sparrelid E., Spüntrup E., Stavrou G.A., Sutcliffe R.P., Tancredi I., Tasse J.C., Udupa V., Valenti D., Fundora Y., Vogl T.J., Wang X., White S.A., Wohlgemuth W.A., Yu D., Zijlstra I.A.J., Binkert C.A., Bemelmans M.H.A., van der Leij C., Schadde E., van Dam R.M.  Dragon 1 Protocol Manuscript: Training, Accreditation, Implementation and Safety Evaluation of Portal and Hepatic Vein Embolization (PVE/HVE) to Accelerate Future Liver Remnant (FLR) Hypertrophy 2022,1391:1398-45.
Korenblik R., Van Zon J.F.J.A., Olij B., Heil J., Dewulf M.J.L., Neumann U.P., Olde Damink S.W.M., Binkert C.A., Schadde E., Van Der Leij C., Van Dam R.M., Aldrighetti L.A., Van Baardewijk L.J., Barbier L., Binkert C.A., Billingsley K., Björnsson B., Andorrà E.C., Arslan B., Baclija I., Bemelmans M.H.A., Bent C., De Boer M.T., Bokkers R.P.H., De Boo D.W., Breen D., Breitenstein S., Bruners P., Cappelli A., Carling U., Robert M.C.I., Chan B., De Cobelli F., Choi J., Crawford M., Croagh D., Van Dam R.M., Deprez F., Detry O., Díaz-Nieto R., Dili A., Erdmann J.I., Font J.C., Davis R., Delle M., Fernando R., Fisher O., Fouraschen S.M.G., Fretland Å.A., Fundora Y., Gelabert A., Gerard L., Gobardhan P., Gómez F., Guiliante F., Grünberger T., Grochola L.F., Grünhagen D.J., Guitart J., Hagendoorn J., Heil J., Heise D., Herrero E., Hess G., Hilal M.A., Hoffmann M., Iezzi R., Imani F., Inmutto N., James S., Borobia F.J.G., Jovine E., Kalil J., Kingham P., Kollmar O., Kleeff J., Lopez-Ben S., MacDonald A., Meijerink M., Lapisatepun W., Leclercq W.K.G., Lindsay R., Lucidi V., Madoff D.C., Martel G., Mehrzad H., Menon K., Metrakos P., Modi S., Moelker A., Montanari N., Moragues J.S., Navinés-López J., Neumann U.P., Nguyen J., Peddu P., Primrose J.N., Olde Damink S.W.M., Qu X., Raptis D.A., Ratti F., Ryan S., Ridouani F., Rinkes I.H.M.B., Rogan C., Ronellenfitsch U., Serenari M., Salik A., Sallemi C., Sandström P., Martin E.S., Sarría L., Schadde E., Serrablo A., Settmacher U., Smits J., Smits M.L.J., Snitzbauer A., Soonawalla Z., Sparrelid E., Spuentrup E., Stavrou G.A., Sutcliffe R., Tancredi I., Tasse J.C., Teichgräber U., Udupa V., Valenti D.A., Vass D., Vogl T.J., Wang X., White S., De Wispelaere J.F., Wohlgemuth W.A., Yu D., Zijlstra I.J.A.J.  Resectability of bilobar liver tumours after simultaneous portal and hepatic vein embolization versus portal vein embolization alone: meta-analysis 2022,:-6.
Law CK, Stevenson ARL, Solomon M, Hague W, Wilson K, Simes JR, Morton RL, the Australasian Gastro-Intestinal Trials Group (AGITG) ALaCaRT investigators. ASO Author Reflections: Is Laparoscopic-Assisted Surgery More Costly than Traditional Open Resection for Rectal Cancer Treatment? Annals of Surgical Oncology 2022; 29:1935-1936.
Law CK, Stevenson ARL, Solomon M, Wilson K, Simes JR, Morton RL and the Australasian GastroIntestinal Trials Group (AGITG) ALaCaRT Investigators. ASO Visual Abstract: Health Care Costs of Laparoscopic Versus Open Surgery for Rectal Cancer Patients in the First 12 Months: A Secondary End-Point Analysis of the Australasian Laparoscopic Cancer of the Rectum Trial (ALaCaRT). Annals of Surgery 2022; 29:1923-1934
Lim C, Laidsaar-Powell R, Young J, Solomon M, Steffens D, Blinman P, O'Loughlin S, Zhang Y, Butow P. Fear of cancer progression and death anxiety in survivors of advanced colorectal cancer: A qualitative study exploring coping strategies and quality of life. OMEGA - Journal of Death and Dying. 2022; DOI: 10.1177/00302228221121493
Lim C, Laidsaar-Powell R, Young J, Solomon M, Steffens D, Yeo D, Blinman P, Koczwara B, Joshy G, Butow P. The advanced-CRC survivorship authorship group, & Butow, P. (2022). The long haul: Lived experiences of survivors following different treatments for advanced colorectal cancer: A qualitative study. European Journal of Oncology Nursing. 2022; 58:102123
Lim CYS, Laidsaar-Powell RC, Young JM, Steffens D, Koczwara B, Zhang Y. The advanced-CRC survivorship authorship group, & Butow, P. Work: Saviour or struggle? A qualitative study examining employment and finances in colorectal cancer survivors living with advanced cancer. Supportive Care in Cancer. DOI: 10.1007/s00520-022-07307-9
Ly M., Lau N.-S., McKenzie C., Kench J.G., McCaughan G., Crawford M., Pulitano C.  The Delay of Arterialization After Initial Portal Reperfusion More Than Warm Ischemia Time May Determine Ischemic-type Biliary Injury 2022,E167:E168-106.
MacDessi SJ, Wernecke GC, Bastiras D, Hooper T, Heath E, Lorimer M, Harris I; RASKAL Study Group. Robotic-assisted surgery and kinematic alignment in total knee arthroplasty (RASKAL study): a protocol of a national registry-nested, multicentre, 2×2 factorial randomised trial assessing clinical, intraoperative, functional, radiographic and survivorship outcomes. BMJ Open. 2022 Jun 10;12(6):e051088.
Mackay I, Clark DA, Nicholson J, Edmundson A, Steffens D, Solomon M.  Risk taking propensity: Nurse, surgeon and patient preferences for diverting ileostomy. Colorectal Disease 2022; 24;1073-1079; DOI: 10.1111/codi.16149
Makary J, McClintock G, Fallot J, Broe M, Ahmadi N, Leslie S and Thanigasalam R. Video guide of robotic assisted laparoscopic prostatectomy post renal transplant: Unique considerations. Urology Video Journal, 2022.
Makary J, van Diepen DC, Arianayagam R, McClintock G, Fallot J, Leslie S, Thanigasalam R. The evolution of image guidance in robotic-assisted laparoscopic prostatectomy (RALP): a glimpse into the future. J Robot Surg. 2022 Aug;16(4):765-774. 
Makker PGS, Koh C, Solomon M, Steffens D. Preoperative functional capacity and postoperative outcomes following abdominal and pelvic cancer surgery - a systematic review and meta-analysis. (Review article) ANZ Journal of Surgery. 2022; 92:1658-1667
Makker PGS, Koh CE, Ansari N, Gonzaga N, Bartyn J, Solomon M, Steffens D. ASO Visual Abstract: Functional outcomes of cytoreductive surgery and hyperthermic intraperitoneal chemotherapy - a prospective cohort study. Annals of Surgical Oncology. 2022: DOI: 10.1245/s10434-022-12691-x
Makker PGS, Koh CE, Steffens D. ASO Author Reflections: Pre-operative Function Status Predicts Post-operative Outcomes in Patients Undergoing Cytoreductive Surgery and Hyperthermic Intra-peritoneal Chemotherapy. Annals of Surgical Oncology. 2022: DOI: 10.1245/s10434-022-12750-3
Makker PGS, Steffens D. ASO Visual Abstract: Functional Outcomes of Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy-A Prospective Cohort Study. Annals of Surgical Oncology. 2022: 10.1245/s10434-022-12801-9
McGiffin T, Clark DA, Edmundson A, Steffens D, Stevenson A, Solomon M.  Surgical management and long-term functional outcomes after anastomotic leak in patients undergoing minimally invasive restorative rectal resection and without a diverting ileostomy.  ANZ Journal of Surgery 2022; 92:806-812
Mercieca-Bebber R et al.  Patient-reported bowel, urinary and sexual outcomes after Laparoscopic-assisted Resection or Open Resection for Rectal Cancer: The Australasian Laparoscopic Cancer of the Rectum Randomized Clinical Trial (ALaCart). Annals of Surgery 2022; DOI: 10.1097/SLA.0000000000005412
Ng K-S, Lee PJM. (Erratum) Pelvic exenteration: Pre-, intra-, and post-operative considerations. Surgical Oncology 2022; 43,101787
Orsi AD, Wakelin EA, Plaskos C, Gupta S, Sullivan JA. Predictive Gap-balancing Reduces the Extent of Soft-tissue Adjustment Required After Bony Resection in Robot-assisted Total Knee Arthroplasty-A Comparison With Simulated Measured Resection. Arthroplast Today. 2022 May 20;16:1-8.
Oswald A, McBride K, Seif S, Koh C, Ansari N, Steffens D.  Depression, anxiety, stress and distress following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: Results of a prospective cohort study. Journal of Clinical Psychology in Medical Settings. 2022; DOI: 10.1007/s10880-022-09918-0
Palma C.A., Watson G., Earls P., Patanjali N., Laurence J., Leslie S.  A novel case of hereditary leiomyomatosis- associated renal cell carcinoma with metastasis to pituitary gland 2022,:-45.
Paredes SR, Smigielski M, Stalley PD, Lee PJ. Pelvic exenteration with high sacrectomy and reconstruction with 3D-printed prosthesis for recurrent sacral chordoma. ANZ J Surg. 2022 Jul 29.
PelvEx Collaborative. Minimum standards of pelvic exenterative practice: PelvEx Collaborative guideline. British Journal of Surgery 2022; 109:1251-1263.
Pillinger N, Koh C, Ansari N, Munoz P, McNamara S, Steffens D. Preoperative cardiopulmonary exercise testing improves risk assessment of morbidity and length of stay following cytoreductive surgery with hyperthermic intraperitoneal chemotherapy. Anaesthesia and Intensive Care. 2022; DOI: 10.1177/0310057X211064904
Putnis SE, Klasan A, Oshima T, Grasso S, Neri T, Coolican MRJ, Fritsch BA, Parker DA. Magnetic Resonance Imaging Assessment of Hamstring Graft Healing and Integration 1 and Minimum 2 Years after ACL Reconstruction. Am J Sports Med. 2022 Jul;50(8):2102-2110.
Risbey C, Fielder T, Steffens D, Joo-Shik S, Solomon M. Patterns of DNA mismatch repair protein expression for primary and recurrent colorectal cancer at an advanced surgical unit: a retrospective audit. Colorectal Disease 2022; 00:1-6; DOI: 10.1111/codi.16391
Robertson TJ, McCulloch TJ, Paleologos MS, Downey RG, Loadsman JA, Thanigasalam R, Leslie S. Effects of sevoflurane versus propofol on cerebral autoregulation during anaesthesia for robot-assisted laparoscopic prostatectomy. Anaesth Intensive Care. 2022 Sep;50(5):361-367. 
Sethi V, Van der Laan L, Gupta S, Piros KC. Perspectives of Healthcare Professionals Towards Combination Use of Oral Paracetamol and Topical Non-Steroidal Inflammatory Drugs in Managing Mild-to-Moderate Pain for Osteoarthritis in a Clinical Setting: An Exploratory Study. J Pain Res. 2022 Aug 6;15:2263-2272.
Siu AHY, Carey S, Jones LH, Morton R, Koh C.  Detailed analysis of in-hospital costs for adult patients with Type III intestinal failure. A single centre study with global implications. Journal of Parenteral and Enteral Nutrition 2022; 46:685-692; DOI:10.1002/jpen.2136
Smigielski M, Ng KS, Lee P. Robotic extra-sphincteric pelvic floor excision: A Video Vignette. Colorectal Dis. 2022 Mar;24(3):339.
Solomon MJ, Alamadi R, Lee PJ, Austin KKS.  En-Bloc Partial Pubic Bone Excision with Complete Soft Tissue Pelvic Exenteration. (Research Letter & Video) British Journal of Surgery 2022; 109:640-641; DOI:10.1093/bjs/znac122
Spolverato G., Capelli G., Lorenzoni G., Gregori D., He J., Popescu I., Marques H.P., Aldrighetti L., Maithel S.K., Pulitano C., Bauer T.W., Shen F., Poultsides G.A., Soubrane O., Martel G., Koerkamp B.G., Itaru E., Lv Y., Pawlik T.M.  Dynamic Prediction of Survival After Curative Resection of Intrahepatic Cholangiocarcinoma: A Landmarking-Based Analysis 2022,7634:7641-29.
Steffens D, Denehy L. Prehabilitation exercise programs for patients undergoing cancer surgery, does one size fit all? European Journal of Surgical Oncology 2022; (Accepted 29 November)
Steffens D, Karunaratne S, McBride K, Gupta S, Horsley M, Fritsch B. Implementation of robotic-assisted total knee arthroplasty in the public health system: a comparative cost analysis. Int Orthop. 2022 Mar;46(3):481-488.
Steffens D, Solomon MJ, Beckenkamp PR, Koh CE, Yeo D, Sandroussi C, Toms C, Blyth H, Murray S, Venchiarutti R, Fox O , Benicio K, Bartyn J, Stanislaus C, O'Connor L, Bourrigan L, Ha C, Kirpichnikov A, Plunkett J, Laurence J, Joseph D, Pulitano C, Crawford M, Hancock M. Individualised, targeted step count intervention following gastrointestinal cancer surgery: The Fit-4-Home randomised clinical trial. ANZ Journal of Surgery. 2022; 92:703-711; DOI: 10.1111/ans.17212
Steffens D, Young J, Riedel B, Morton R, Denehy L, Heriot A, Koh C, Li Q, Bauman A, Sandroussi C, Ismail H, Dieng M, Ansari N, Pillinger N, O'Shannassy S, Mckeown S, Cunningham D, Sheehan K,  Iori G, Bartyn J, Solomon M. PRehabIlitatiOn with pReoperatIve exercise and educaTion for patients undergoing major abdominal cancer surgerY: Protocol for a multicentre randomised controlled TRIAL (PRIORITY TRIAL). BMC Cancer 2022; 22:443: DOI: 10.1186/s12885-022-09492-6
Steinberg J, Chan P, Hogden E, Tiernan G, Morrow A, Kang Y-J, He E, Venchiarutti R, Titterton L, SankeyL, Pearn A, Nichols C, McKay S, Hayward A, Egoroff N, Engel A, Gibbs P, Goodwin A, Harris M, Kench J, Pachter N, Parkinson B, Pockney P, Ragunathan A, Smyth C, Solomon M, Steffens D, Toh J, Wallace M, Canfell K, Gill A, Macrae F, Tucker K, Taylor N. Lynch syndrome testing of colorectal cancer patients in a high-income country with universal healthcare: a retrospective study of current practice and gaps in seven Australian hospitals. Hereditary Cancer in Clinical Practice. 2022; DOI:10.1186/s13053-022-00225-1
Strach MC, Grimison PS, Hong A, Boyle R, Stalley P, Karim R, Connolly EA, Bae S, Desai J, Crowe P, Singhal N, Bhadri VA. Mesenchymal chondrosarcoma: An Australian multi-centre cohort study. Cancer Med. 2022 May 23.
Sutton PA, Brown KGM, Ebrahimi N, Solomon MJ. Long term surgical complications following pelvic exenteration - operative management of the empty pelvis syndrome. Colorectal Disease 2022; DOI: 10.1111/codi.16238
Tan M.M.C., Jin X., Taylor C., Low A.K., Le Page P., Martin D., Li A., Joseph D., Kormas N.  Long-Term Trajectories in Weight and Health Outcomes Following Multidisciplinary Publicly Funded Bariatric Surgery in Patients with Clinically Severe Obesity (≥ 3 Associated Comorbidities): A Nine-Year Prospective Cohort Study in Australia 2022,:-11.
Tsilimigras D.I., Ejaz A., Cloyd J., Guglielmi A., Aldrighetti L., Weiss M., Bauer T.W., Alexandrescu S., Poultsides G.A., Maithel S.K., Marques H.P., Martel G., Pulitano C., Shen F., Soubrane O., Koerkamp B.G., Endo I., Pawlik T.M.  Tumor Necrosis Impacts Prognosis of Patients Undergoing Resection for T1 Intrahepatic Cholangiocarcinoma 2022,4326:4334-29.
Van Kessel CS, Solomon MJ. Understanding the Philosophy, Anatomy, and Surgery of the Extra-TME Plane of Locally Advanced and Locally Recurrent Rectal Cancer; Single Institution Experience with International Benchmarking. (Review) Cancers 2022; 14:5058: doi.org/10.3390/cancers14205058
Wei T., Zhang X.-F., He J., Popescu I., Marques H.P., Aldrighetti L., Maithel S.K., Pulitano C., Bauer T.W., Shen F., Poultsides G.A., Soubrane O., Martel G., Koerkamp B.G., Itaru E., Lv Y., Pawlik T.M.  Prognostic impact of perineural invasion in intrahepatic cholangiocarcinoma: multicentre study 2022,610:616-109.
Xu J., D'Souza K., Lau N.S., Leslie S., Lee T., Yao J., Lam S., Sandroussi C., Chadban S., Ying T., Pleass H., Laurence J.M.  Staged versus concurrent native nephrectomy and renal transplantation in patients with autosomal dominant polycystic kidney disease: A systematic review 2022,:-36.
Zadro JR, Karunaratne S, Harris IA, Jones CMP, O'Keeffe M, Ferreira GE, Buchbinder R, McCaffery K, Thompson R, Maher CG, Hoffmann T. The impact of a patient decision aid on intention to undergo surgery for subacromial pain syndrome: An online randomised controlled trial. Patient Education and Counseling 2022; 105:2951-2961; DOI: 10.1016/j.pec.2022.05.005
Zhou DDX, King D, Thomson K, Grimison P. Trabectedin for metastatic liposarcoma and leiomyosarcoma: Comparison of real-world experience in an Australian sarcoma specialist center to pivotal clinical trial results. Asia-Pac J Clin Oncol, 18: e526-e528