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Surgical Outcomes Research Centre (SOuRCe)

The Surgical Outcomes Research Centre (SOuRCe) was establishment in 2002 and has aimed to promote an evidence-based approach to improve clinical practice and achieve the best possible outcome for patients. As a multidisciplinary, academic research unit of Sydney Local Health District and the University of Sydney; our research agenda addresses diverse aspects of surgical outcomes, including surgical effectiveness, patient reported outcomes and quality of life, patterns of care and evidence-based practice, health economic evaluation, assessment of patient preferences, surgical decision-making and other methodological studies. 

Overall Research Output
Currently, SOuRCe is involved in 250 research studies in collaboration with multi-specialty surgical departments, allied health, nursing, other academics and consumers, based in Australia and Internationally. Over 55% of our research studies are registry-nested and originate from comprehensive data collected from the funded surgical programs, including the Advanced Gastrointestinal Research Program, Robotics Program, Orthopaedic Surgery and Vascular Surgery Programs. The other 45% of our research originates from historical collaborations within the following departments: colorectal, transplant, urology, ear, nose and throat, orthopaedics, upper gastrointestinal, breast, vascular, allied health, head and neck, anaesthetics, nursing, benign gynaecology, pathology, imaging, pharmacy and other departments and institutions.

Over the past 22 years, SOuRCe has rapidly developed to become one of the major Australian surgical research units, and is now a centre of surgical research excellence with international recognition. During this time, SOuRCe was awarded over $30M in competitive funding, including major funding bodies such as the NHMRC, MRFF, CINSW, NIHR and others. SOuRCe has published over 700 peer-reviewed scientific articles in the top surgical and medical journals, including NATURE, BMJ, JAMA surgery, Annals of Surgery, The British Journal of Surgery, Journal of Surgical Oncology and other high impact journals. SOuRCe has supervised over 70 PhD and MPHIL students and over 60 MD students. These achievements have contributed significantly to the enhancement of patient outcomes and have changed clinical practice at RPA, Australia and Internationally.

Funded Research Programs
Our funded surgical research programs include the Advanced Gastrointestinal Surgical Program (including Pelvic Exenteration, Peritoneal Malignancy, Retroperitoneal Sarcoma and Advanced Upper Gastrointestinal Surgery), Robotics Program, Orthopaedic Surgery (including the Bone and Soft Tissue Tumour Program), Vascular Surgery, and the Preoperative Optimisation Research Program. Most of the funded research programs are governed by the RPA Institute of Academic Surgery and are led by a large amount of multidisciplinary and multispecialty groups of clinical and non-clinical staff from a variety of departments across RPA.

Highlights of Surgical Research

Pelvic Exenteration Research Program
Pelvic exenteration is complex, radical surgery for advanced or recurrent pelvic cancers. The Royal Prince Alfred Hospital is one of the few hospitals in Australia that performs large numbers of this surgery and has evolved over 30 years into an internationally recognised centre of excellence.

Currently, SOuRCe holds the largest database in the world capturing clinical and patient reported outcomes of all pelvic exenterations performed at the Royal Prince Alfred Hospital. With over 50 ongoing research projects, the Pelvic Exenteration Research Program has extensively contributed to the development of the current clinical practice worldwide. Under the leadership of Prof Michael Solomon, the Pelvic Exenteration Program is celebrating the completion of the 1000th pelvic exenteration in 2022. This is a remarkable milestone for the program and is credited to the large group of multidisciplinary staff involved in the delivery of the Pelvic Exenteration Surgical Program. 

Peritoneal Malignancy Research Program
The Peritoneal Malignancy program at the Royal Prince Alfred Hospital is included in SOuRCe's research profile, with Cytoreductive Surgery & Hyperthermic Intraperitoneal Chemotherapy (CRS & HIPEC), performed to treat advanced cancers involving the lining of the abdomen. 

The research program started at the beginning of 2017 and undertakes detailed analysis toward better understanding the clinical outcomes, patient reported outcomes, safety benefits and cost effectiveness of this highly specialised procedure. The data collected by SOuRCe is also used to identify specific patient groups who are more likely to benefit from this highly specialised surgery. To date, more than 500 procedures have been performed at the Royal Prince Alfred Hospital, with most patients being followed up to 5-years, including measures of quality of life and health service utilisation. The comprehensive data collection is currently contributing to over 35 research projects, including major clinical trials and international collaborations.

Robotic Research Program
In late 2015, Sydney Local Health District (SLHD) announced the purchase of a da Vinci Xi Surgical Robot and a Stryker Mako Orthopaedic Surgical Robot for use in the Royal Prince Alfred Hospital and Institute of Rheumatology and Orthopaedics operating theatres. RPAH is one of the first public tertiary referral hospitals in Australia to have this state-of-the-art technology available. The following surgical specialties are currently utilising the da Vini Xi system: Cardiothoracic, Colorectal, Urology, Upper Gastrointestinal and Benign Gynaecology. 

Currently, over 800 procedures have been performed using the da Vinci robot and 700 using the Mako robotic system. The unique research framework within the Robotic Research Program at the Royal Prince Alfred Hospital, allow the collection of clinical and quality of life measures for all robotic cases. This approach resulted in the development of more than 40 research projects across multi disciplines.

Bone and Soft Tissue Tumour Surgical Research Program 
The Bone and Soft Tissue Tumour Surgical Research Program, led by the Surgical Outcomes Research Centre (SOuRCe) in collaboration with the Royal Prince Alfred Hospital (RPA) Institute of Academic Surgery, is the newest addition to SOuRCe's research profile. The program was formalised in 2023 and works in partnership with the RPA Bone & Soft Tissue Sarcoma Unit – a world leader in the diagnosis, treatment and follow-up of suspected sarcoma. This program drives advances in scientific knowledge through a robust and comprehensive research initiative, while also informing evidence-based practices. The research conducted contributes to the development of cutting-edge methodologies and expands our understanding in the field, ultimately aiming to provide the best possible outcomes to our patients.

The program has a unique approach, collecting clinical, surgical and patient reported outcomes for all patients undergoing treatment at RPA. This comprehensive information is entered into a secured online database (RPA Outcomes in Bone and Soft Tissue Tumours – ROBUST), which spans from baseline (before surgery) through 10 years post-surgery, and supports ongoing evaluation of patient outcomes across a number of research initiatives and clinical trials. 

Our Research Team

Our Directors

 
Professor Michael Solomon Funder and Head of the Surgical Outcomes Research Centre (SOuRCe);
Academic Head and Surgeon, Department of Colorectal Surgery, Royal Prince Alfred Hospital;
Co-Chairman, RPA Institute of Academic Surgery (IAS);
Professor of Surgical Research, University of Sydney.
Dr Kate McBride Director of the Surgical Outcomes Research Centre (SOuRCe); Director of Operations for the Surgical Program.
Associate Professor Daniel Steffens Director of the Surgical Outcomes Research Centre (SOuRCe). 

Our Expert Advisors

 
Associate Professor Charbel Sandroussi Director of Clinical Research at the RPA Institute of Academic Surgery;
Head of Department of Hepatobiliary and Upper Gastrointestinal Surgery, Royal Prince Alfred Hospital.
Associate Professor Cherry Koh Associate Professor of Surgical Outcomes, University of Sydney;
Research Lead for Colorectal Surgery at the RPA Institute of Academic Surgery.
Dr David Yeo Upper Gastrointestinal, Hepatobiliary and Transplant Surgeon, Royal Prince Alfred Hospital. 
Dr Sharon Carey Nutrition and Dietetics, Royal Prince Alfred Hospital.
Professor Ian Harris Orthopaedic Surgeon;
Honorary Professor, School of Public Health, Faculty of Medicine & Health, University of Sydney.
Professor Kate White Professor Cancer Nursing, Cancer Nursing Research Unit (CNRU) / Susan Wakil School of Nursing and Midwifery / Sydney Nursing School, The Daffodil Centre, Faculty of Medicine and Health

Our Research Staff

 
Sascha Karunaratne Research Manager
Kate Alexander Research Manager
Madhu Prasad Administrative Officer
Jacob Bird Robotic Surgery Research Officer
Lylee Ye Retroperitoneal Saracoma Research Officer
Philip Hay iCAD Trial Coordinator, Orthopaedic Research Officer
Claire Jeon PRIORITY-CONNECT 2 Trial Research Officer
Josielli Comachio PRIORITY Trial Research Officer

Selected Grants

Amount awarded Grant and project details
$4,995,331 MRFF, 2024-2029
Virtual Multimodal Hub for Patients Undergoing Major Gastrointestinal Cancer Surgery – PRIORITY-CONNECT 2 Randomised Type I Hybrid Effectiveness-Implementation Trial.
Investigator: Steffens D.
$120,000 The University of Sydney, 2024-2027
PRIORITY-CONNECT SMS - Enhancing upper gastrointestinal cancer surgery recovery with AI-driven avatar-based video multidisciplinary intervention.
Investigators: Beckenkamp P, Sandroussi C, Boscolo A, Solomon M, Hush J,  Steffens D.
$250,000 Sydney Cancer Partners, 2024-2026
A Community-Partnered Co-Designed Intervention to Enhance Recruitment of Aboriginal peoples in Cancer Surgical Trials.
Investigators: Koh C, Lyons R, Rutherford C, Smith B, Alexander K, Karunaratne S, White K, Kim B, Solomon M, Cunich M, Steffens D.
$4,744,165 NHMRC Clinical Trials and Cohort Studies, 2023-ongoing
ROADMAP: RandOmisedArthroplasty infection worlDwide Multidomain Adaptive Platform trial.
Investigator: Harris I.
$170,000 ANZSA Clinical Research Fellowship, The Kid’s Cancer Project and Rainbows For Kate Foundation, 2022-2024
ANZSA Clinical Research Fellowship
Investigator: Strach M.
$901,695 MRFF 2020 Rare Cancers, Rare Diseases and Unmet Need, 2020-ongoing
A randomized phase III study of neoadjuvant chemotherapy followed by surgery versus surgery alone for patients with High Risk RetroPeritoneal Sarcoma (STRASS 2).
Investigators: Gyorki D, Grimison P, Hofman M, Blinman P, Barbour A,  Gronchi A, Snow H.
$998,609 MRFF 2021 Rare Cancers, Rare Diseases and Unmet Need, 2021-2024
INTER-EWING-1 International clinical research program to improve outcomes in newly diagnosed Ewing Sarcoma patients Trial 1.
Investigators: McCowage G, Desai J, Phillips M, Ryan J, Hong A, Lewin J, Kirby M, Brennan B, Strong T, Stalley P.
$1,119,877 NHMRC, 2020-2024
PRIORITY TRIAL - Preoperative exercise for patients undergoing major abdominal cancer surgery: A Multicentre Randomised Controlled Trial
Investigators: Young J, Solomon MJ, Riedel B, Steffens D, Morton R, Denehy L, Heriot A, Koh C, Li Q, Bauman A

Our Publications

2024

Li A, Stanislaus CT, Steffens D, McBride KE, Leslie S, Thanigasalam R, Cunich M. Prospective cohort study investigating quality of life outcomes following multi-speciality robotic-assisted surgery. J Minim Access Surg. 2024 Jan 1;20(1):37-46. doi: 10.4103/jmas.jmas_253_22. Epub 2023 Apr 13.
Favaloro J, Bryant CE, Abadir E, Gardiner S, Yang S, King T, Nassif N, Sedger LM, Boyle R, Joshua DE, Ho PJ. Single-cell analysis of the CD8+ T-cell compartment in multiple myeloma reveals disease specific changes are chiefly restricted to a CD69- subset suggesting potent cytotoxic effectors exist within the tumor bed. Haematologica. 2024 Apr 1;109(4):1220-1232. doi: 10.3324/haematol.2023.283062.
Brown KGM, Ng KS, Solomon MJ, Chapuis PH, Koh CE, Ahmadi N, Austin KKS. Complete mesocolic excision for colon cancer: current status and controversies. ANZ J Surg. 2024 Mar;94(3):309-319. doi: 10.1111/ans.18741. Epub 2023 Oct 18.
Austin KKS, Brown KGM, Solomon MJ. En bloc lateral pelvic compartment excision during pelvic exenteration: video vignette. Br J Surg. 2024 Jan 3;111(1):znad407. doi: 10.1093/bjs/znad407.
Karunaratne S, Harris IA, Horsley M, Trevena L, Solomon M. Establishing a hierarchy of total knee arthroplasty patients' goals and its congruity to health professionals' perceptions: a cohort study. ANZ J Surg. 2024 Feb;94(1-2):234-240. doi: 10.1111/ans.18817. Epub 2023 Dec 10.
Brown KGM, Pisaniello J, Ng KS, Solomon MJ, Sutton PA, Hatcher S, Steffens D. Variation in outcome measurement and reporting in studies of pelvic exenteration for locally advanced and recurrent rectal cancer: a systematic review. Colorectal Dis. 2024 Feb;26(2):272-280. doi: 10.1111/codi.16844. Epub 2023 Dec 22.
Brown KGM, Solomon MJ. Topical haemostatic agents in surgery. Br J Surg. 2024 Jan 3;111(1):znad361. doi: 10.1093/bjs/znad361.
Steffens D, Blake J, Solomon MJ, Lee P, Austin KKS, Byrne CM, Karunaratne S, Koh CE. Trajectories of Quality of Life After Pelvic Exenteration: A Latent Class Growth Analysis. Dis Colon Rectum. 2024 Apr 1;67(4):531-540. doi: 10.1097/DCR.0000000000003080. Epub 2023 Dec 29.
Brown KGM, Solomon MJ, Sutton PA, Shin JS, Steffens D. The definition of clear resection margins in locally recurrent rectal cancer-time for consensus. Br J Surg. 2024 Jan 3;111(1):znad450. doi: 10.1093/bjs/znad450.
Hirst N, McBride K, Steffens D. Psychological Interventions in Prehabilitation Randomized Controlled Trials for Patients Undergoing Cancer Surgery: Sufficient or Suboptimal? Ann Surg Oncol. 2024 Apr;31(4):2183-2186. doi: 10.1245/s10434-023-14853-x. Epub 2024 Jan 20.
Badhwar V, Pereda D, Khaliel FH, Poffo R, Darehzereshki A, Mehaffey JH, Yan TD, Melnitchouk S, Geirsson A, Arghami A, Navia JL, Raikar GV, Weber AC, Ramzy D, Černý Š, Vojáček J, Smith RL, Bonatti J, Thourani VH, Wei LM. Outcomes following initial multicenter experience with robotic aortic valve replacement: Defining a path forward. J Thorac Cardiovasc Surg. 2024 Apr;167(4):1244-1250. doi: 10.1016/j.jtcvs.2024.01.020. Epub 2024 Jan 19.
Brown KG, Ansari N, Solomon MJ. Contemporary management of advanced colorectal cancer: the Australian experience. Med J Aust. 2024 Mar 18;220(5):222-224. doi: 10.5694/mja2.52218. Epub 2024 Jan 28. Erratum in: Med J Aust. 2024 May 6;220(8):406. doi: 10.5694/mja2.52275.
Jiang W, Brown KGM, Koh C, Karunaratne S, Solomon M, Beckenkamp PR, Cole R, Steffens D. Outcome Heterogeneity in Prehabilitation Trials-Are We Comparing Apples and Oranges? J Surg Res. 2024 Apr;296:366-375. doi: 10.1016/j.jss.2023.12.042. Epub 2024 Feb 2.
McClintock G, Goolam AS, Perera D, Downey R, Leslie S, Grimison P, Woo H, Ferguson P, Ahmadi N. Robotic-assisted retroperitoneal lymph node dissection for stage II testicular cancer. Asian J Urol. 2024 Jan;11(1):121-127. doi: 10.1016/j.ajur.2022.03.010. Epub 2022 Jul 30.
Teng MJ, Zadro JR, Pickles K, Copp T, Shaw MJ, Khoudair I, Horsley M, Warnock B, Hutchings OR, Petchell JF, Ackerman IN, Drayton A, Liu R, Maher CG, Traeger AC. RECITAL: a non-inferiority randomised control trial evaluating a virtual fracture clinic compared with in-person care for people with simple fractures (study protocol). BMJ Open. 2024 Feb 5;14(2):e080800. doi: 10.1136/bmjopen-2023-080800.
PelvEx Collaborative. Beating the empty pelvis syndrome: the PelvEx Collaborative core outcome set study protocol. BMJ Open. 2024 Feb 5;14(2):e076538. doi: 10.1136/bmjopen-2023-076538.
Siu A, Steffens D, Ansari N, Karunaratne S, Solanki H, Ahmadi N, Solomon M, Moran B, Koh C. Evaluating geographical disparities on clinical outcomes following cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Tech Coloproctol. 2024 Feb 20;28(1):35. doi: 10.1007/s10151-024-02911-9.
van Kessel CS, Palma CA, Solomon MJ, Leslie S, Jeffery N, Lee PJ, Austin KKS. Comparison of urological outcomes and quality of life after pelvic exenteration: partial vs radical cystectomy. BJU Int. 2024 Apr;133 Suppl 4:53-63. doi: 10.1111/bju.16299. Epub 2024 Feb 20.
Ebrahimi N, Brown KGM, Ng KS, Solomon MJ, Lee PJ. Impact of Intraoperative Decision-Making on Pathological Margin Status in Patients Undergoing Pelvic Exenteration for Locally Recurrent Rectal Cancer. Dis Colon Rectum. 2024 Aug 1;67(8):1024-1029. doi: 10.1097/DCR.0000000000003131. Epub 2024 Feb 21.
Waller JH, van Kessel CS, Solomon MJ, Lee PJ, Austin KKS, Steffens D. Outcomes Following Pelvic Exenteration for Locally Recurrent Rectal Cancer With and Without En Bloc Sacrectomy. Dis Colon Rectum. 2024 Jun 1;67(6):796-804. doi: 10.1097/DCR.0000000000003154. Epub 2024 Feb 23.
Steffens D, Ansari N, Koh C, Ahmadi N, Solomon MJ, Hogan S, Karunaratne S, Anderson T, Harvey K, McBride K, Moran B. Complexity of surgery and treatment burden in patients with peritoneal malignancy is not determined by addition of hyperthermic intraperitoneal chemotherapy. ANZ J Surg. 2024 Apr;94(4):628-633. doi: 10.1111/ans.18933. Epub 2024 Mar 7.
PelvEx Collaborative. The empty pelvis syndrome: a core data set from the PelvEx collaborative. Br J Surg. 2024 Mar 2;111(3):znae042. doi: 10.1093/bjs/znae042. Erratum in: Br J Surg. 2024 Mar 2;111(3):znae095. doi: 10.1093/bjs/znae095.
Garrett C, Steffens D, Solomon M, Koh C. Surgical and survival outcomes of early-onset colorectal cancer patients: a single-centre descriptive Australian study. ANZ J Surg. 2024 Sep;94(9):1584-1589. doi: 10.1111/ans.18938. Epub 2024 Mar 12.
Murphy GT, Le M, Frangos Young A, Le M, Guzman MS, Franks D, Boyle R, Stalley P. Unique case of a broken axle in a GMRS tumour prosthesis: insights and challenges. ANZ J Surg. 2024 May;94(5):970-972. doi: 10.1111/ans.18940. Epub 2024 Mar 12.
Giddings HL, Ng KS, Solomon MJ, Steffens D, Van Buskirk J, Young J. High but decreasing rates of reconstruction after total proctocolectomy for ulcerative colitis, and evidence of a direct volume outcome relationship. ANZ J Surg. 2024 Sep;94(9):1598-1609. doi: 10.1111/ans.18986. Epub 2024 Mar 25.
Steffens D, Solomon M, Dubowitz J, Martis W, Ismail H, Koh C, Riedel B. Augmented prehabilitation - is there a role for glucocorticoids and/or anabolic steroids to improve surgical outcomes? ANZ J Surg. 2024 Jun;94(6):989-992. doi: 10.1111/ans.18989. Epub 2024 Mar 25.
Broekhuis D, Meurs WMH, Kaptein BL, Karunaratne S, Carey Smith RL, Sommerville S, Boyle R, Nelissen RGHH. High accuracy of positioning custom triflange acetabular components in tumour and total hip arthroplasty revision surgery. Bone Jt Open. 2024 Apr 1;5(4):260-268. doi: 10.1302/2633-1462.54.BJO-2023-0185.R1.
PelvEx Collaborative. Contemporary results from the PelvEx collaborative: improvements in surgical outcomes for locally advanced and recurrent rectal cancer. Colorectal Dis. 2024 May;26(5):926-931. doi: 10.1111/codi.16948. Epub 2024 Apr 2.
Webster S, Vargas AC, Maclean F, Vu J, Tong E, Coker D, Ward I, Connolly EA, Zhou DD, Mar J, Lazarakis S, Gyorki DE, Hong AM. What is the association of preoperative biopsy with recurrence and survival in retroperitoneal sarcoma? A systematic review by the Australia and New Zealand Sarcoma Association clinical practice guidelines working party. Crit Rev Oncol Hematol. 2024 May;197:104354. doi: 10.1016/j.critrevonc.2024.104354. Epub 2024 Apr 13.
CRISTAL Study Group. Aspirin or enoxaparin for VTE prophylaxis after primary partial, total or revision hip or knee arthroplasty: A secondary analysis from the CRISTAL cluster randomized trial. PLoS One. 2024 Apr 16;19(4):e0298152. doi: 10.1371/journal.pone.0298152.
McBride KE, Torzillo J, Davis R, Steffens D, Wand T, Sanders RD, Glozier N, Solomon MJ. Mental illness comorbidity significantly impacts surgical outcomes for emergency surgical patients. ANZ J Surg. 2024 Jul-Aug;94(7-8):1341-1348. doi: 10.1111/ans.19008. Epub 2024 Apr 25.
Jeys LM, Thorkildsen J, Kurisunkal V, Puri A, Ruggieri P, Houdek MT, Boyle RA, Ebeid W, Botello E, Morris GV; BOOM Consensus Scientific Committee; Laitinen MK; BOOM Consensus Scientific Committee; Abudu A, Ae K, Agarwal M, Ajit Singh V, Akiyama T, Albergo JI, Alexander J, Alpan B, Aoude A, Asavamongkolkul A, Aston W, Baad-Hansen T, Balach T, Benevenia J, Bergh P, Bernthal N, Binitie O, Boffano M, Bramer J, Branford White H, Brennan B, Cabrolier J, Calvo Haro JA, Campanacci DA, Cardoso R, Carey Smith R, Casales Fresnga N, Casanova JM, Ceballos O, Chan CM, Chung YG, Clara-Altamirano MA, Cribb G, Dadia S, Dammerer D, de Vaal M, Delgado Obando J, Deo S, Di Bella C, Donati DM, Endo M, Eralp L, Erol B, Evans S, Eward W, Fiorenza F, Freitas J, Funovics PT, Galli Serra M, Ghert M, Ghosh K, Gomez Mier LC, Gomez Vallejo J, Griffin A, Gulia A, Guzman M, Hardes J, Healey J, Hernandez A, Hesla A, Hongsaprabhas C, Hornicek F, Hosking K, Iwata S, Jagiello J, Johnson L, Johnston A, Joo M, Jutte P, Kapanci B, Khan Z, Kobayashi H, Kollender Y, Koob S, Kotrych D, Le Nail LR, Legosz P, Lehner B, Leithner A, Lewis V, Lin P, Linares F, Lozano Calderon S, Mahendra A, Mahyudin F, Mascard E, Mattei JC, McCullough L, Medellin Rincon MR, Morgan-Jones R, Moriel Garcesco DJ, Mottard S, Nakayama R, Narhari P, O'Toole G, Vania O, Olivier A, Omar M, Ortiz-Cruz E, Ozger H, Ozkan K, Palmerini E, Papagelopoulos P, Parry M, Patton S, Petersen MM, Powell G, Puhaindran M, Raja A, Rajasekaran RB, Repsa L, Ropars M, Sambri A, Schubert T, Shehadeh A, Siegel G, Sommerville S, Spiguel A, Stevenson J, Sys G, Temple T, Traub F, Tsuchiya H, Valencia J, Van de Sande M, Vaz G, Velez Villa R, Vyrva O, Wafa H, Wan Faisham Numan WI, Wang E, Warnock D, Werier J, Wong KC, Norio Y, Zhaoming Y, Zainul Abidin S, Zamora T, Zumarraga JP, Abou-Nouar G, Gebert C, Randall RL. Controversies in orthopaedic oncology. Bone Joint J. 2024 May 1;106-B(5):425-429. doi: 10.1302/0301-620X.106B5.BJJ-2023-1381.
Bai Z, Solomon M, Shahab R, Koh C, Steffens D. The good, the bad, and the frail - the role of prehabilitation in frail patients undergoing cancer surgery. ANZ J Surg. 2024 Jun;94(6):993-995. doi: 10.1111/ans.19027. Epub 2024 May 8.
Alexander K, Karunaratne S, Sidhu V, Fritsch B, Gupta S, Horsley M, Guzman M, Boyle R, McBride K, Steffens D. Evaluating the cost of robotic-assisted total and unicompartmental knee arthroplasty. J Robot Surg. 2024 May 8;18(1):206. doi: 10.1007/s11701-024-01932-8.
Zhang O, Irons J, Santibanez J, Cao C. Robotic Thoracic Duct Repair Using Indocyanine Green Guidance. Innovations (Phila). 2024 May-Jun;19(3):321-323. doi: 10.1177/15569845241246565. Epub 2024 May 9.
Murphy GT, Shatz J, Bonar SF, Mahar A, Boyle R. Rate of evolution on imaging of a benign primary bone tumour - giant cell tumour. ANZ J Surg. 2024 Jul-Aug;94(7-8):1409-1411. doi: 10.1111/ans.19029. Epub 2024 May 10.
Giddings HL, Yang PF, Steffens D, Solomon MJ, Ng KS. Influence of hospital-level and surgeon factors on the outcomes after ileo-anal pouch surgery for inflammatory bowel disease: systematic review. Br J Surg. 2024 May 3;111(5):znae088. doi: 10.1093/bjs/znae088.
Garrett C, Koh CE, Solomon MJ, Steffens D. The health-related quality of life of early-onset colorectal cancer patients: an Australian cross-sectional study. Colorectal Dis. 2024 Jun;26(6):1166-1174. doi: 10.1111/codi.16998. Epub 2024 May 14.
Ephraums J, Brown KGM, Solomon MJ, Austin KKS, Lee PJ, Leslie S, Byrne C. Pelvic exenteration for locally advanced and recurrent prostate cancer. Eur J Surg Oncol. 2024 Jul;50(7):108384. doi: 10.1016/j.ejso.2024.108384. Epub 2024 May 7.
Crebert MJ, Kasunic D, Karunaratne SR, Alexander KG, Scholtz AC, Boyle RA, Steffens D. Patient-Reported Outcomes and Range of Motion Following Knee Arthroplasty Using a Megaprosthesis in Non-Oncological Patients: A Systematic Review. J Arthroplasty. 2024 Oct;39(10):2633-2644.e4. doi: 10.1016/j.arth.2024.05.028. Epub 2024 May 15.
Garrett C, Steffens D, Ackland S, Solomon M, Koh C. Risk factors, histopathological landscape, biomarkers, treatment patterns and survival of early-onset colorectal cancer: A narrative review. Asia Pac J Clin Oncol. 2024 Aug;20(4):444-449. doi: 10.1111/ajco.14081. Epub 2024 May 22.
Hush JM, Steffens D, Solomon MJ. A patient-designed integrative oncology intervention for stage IV locally recurrent rectal cancer: A case report. Explore (NY). 2024 Sep-Oct;20(5):103004. doi: 10.1016/j.explore.2024.05.002. Epub 2024 May 21.
Lee PJ, Kim TJ, Ye L, Wu YS, Steffens D, Karunaratne S, Brown W, Karim R, Grimison P, Hong AM. SPARC - A multi-disciplinary team program for retroperitoneal sarcoma: the Royal Prince Alfred Hospital and Chris O'Brien Lifehouse Collaboration. ANZ J Surg. 2024 Jul-Aug;94(7-8):1333-1340. doi: 10.1111/ans.19102. Epub 2024 May 24.
Vu J, Koh C, Solomon M, Brown K, Karunaratne S, Cole R, Smith P, Raichurkar P, Denehy L, Riedel B; Prehabilitation Expert Collaborative; Steffens D. Patients' and carers' views on research priorities in prehabilitation for cancer surgery. Support Care Cancer. 2024 May 24;32(6):378. doi: 10.1007/s00520-024-08585-1.
Karunaratne S, Harris IA, Horsley M, Trevena L, Solomon M. Second opinion in lower limb total joint arthroplasty: do surgeons agree on surgical management? ANZ J Surg. 2024 Jul-Aug;94(7-8):1427-1428. doi: 10.1111/ans.19113. Epub 2024 May 31.
CRISTAL Economic Analysis Study Group. Cost-effectiveness of enoxaparin versus aspirin in the prevention of venous thromboembolism after total hip or knee arthroplasty: an analysis from the CRISTAL cluster-randomized trial. Bone Joint J. 2024 Jun 1;106-B(6):589-595. doi: 10.1302/0301-620X.106B6.BJJ-2023-0783.R2.
Karunaratne S, Harris IA, Horsley M, Trevena L, Solomon M. The achievement of pre-operative expectations in patients undergoing knee arthroplasty: a cohort study evaluating unique patient goals. J Patient Rep Outcomes. 2024 Jun 6;8(1):56. doi: 10.1186/s41687-024-00734-8.
Steffens D, Nott F, Koh C, Jiang W, Hirst N, Cole R, Karunaratne S, West MA, Jack S, Solomon MJ. Effectiveness of Prehabilitation Modalities on Postoperative Outcomes Following Colorectal Cancer Surgery: A Systematic Review of Randomised Controlled Trials. Ann Surg Oncol. 2024 Nov;31(12):7822-7849. doi: 10.1245/s10434-024-15593-2. Epub 2024 Jun 24.
Gibson D, Shanmugasundaram R, McClintock G, Pham C, Hutton A, Ahmadi N, Arianayagam M, Elmes M, Thanigasalam R, Doeuk N, Papadopoulos B, Ngo T, Rathore P, Rasiah K, Thompson J, Aslan P, Treacy PJ, Leslie S. Robotic-Assisted Bladder Diverticulectomy: Indications, Technique, and Outcomes-A Case Series. J Endourol. 2024 Oct;38(10):1013-1020. doi: 10.1089/end.2024.0209. Epub 2024 Jul 22.
Giddings HL, Ng KS, Solomon MJ, Steffens D, Van Buskirk J, Young J. Unexpected variation in outcomes following total (procto)colectomies for ulcerative colitis in New South Wales, Australia: a population-based 19-year linked-data study. Colorectal Dis. 2024 Aug;26(8):1584-1596. doi: 10.1111/codi.17074. Epub 2024 Jun 27.
Harris IA, Sidhu VS, MacDessi SJ, Solomon M, Haddad FS. Aspirin for thromboembolic prophylaxis. Bone Joint J. 2024 Jul 1;106-B(7):642-645. doi: 10.1302/0301-620X.106B7.BJJ-2024-0621.
Steffens D, Solomon MJ, Jack S, West MA. ASO Author Reflections: Improving Postoperative Outcomes in Colorectal Cancer Surgery: Where are We with Prehabilitation? Ann Surg Oncol. 2024 Oct;31(10):6474-6475. doi: 10.1245/s10434-024-15835-3. Epub 2024 Jul 11.
Vu JK, Koh CE. Prehabilitation for Colorectal Cancer Surgery. Dis Colon Rectum. 2024 Oct 1;67(10):1239-1242. doi: 10.1097/DCR.0000000000003456. Epub 2024 Jul 17.
Sena Board M, McBride KE, Solomon MJ, Aitken SJ, Rickard MJFX, Collins JM, Steffens D. Australian surgeon attitudes and experiences towards completing a higher degree by research. Aust Health Rev. 2024 Aug;48(4):406-413. doi: 10.1071/AH23230.
Sitharthan D, Kang S, Treacy PJ, Bird J, Alexander K, Karunaratne S, Leslie S, Chan L, Steffens D, Thanigasalam R. The Sensitivity and Specificity of Multiparametric Magnetic Resonance Imaging and Prostate-Specific Membrane Antigen Positron Emission Tomography/Computed Tomography for Predicting Seminal Vesicle Invasion in Clinically Significant Prostate Cancer: A Multicenter Retrospective Study. J Clin Med. 2024 Jul 29;13(15):4424. doi: 10.3390/jcm13154424.
Brown KGM, Solomon MJ. Understanding Quality of Life After Pelvic Exenteration for Patients with Rectal Cancer. Ann Surg Oncol. 2024 Nov;31(12):7668-7670. doi: 10.1245/s10434-024-16031-z. Epub 2024 Aug 13.
Dowsett G, Murphy G, Le M, Chopra S, Sivaji S, Franks D, Boyle R, Guzman M. Combined intra and extraosseous schwannoma of the calcaneus. ANZ J Surg. 2024 Sep;94(9):1657-1659. doi: 10.1111/ans.19139. Epub 2024 Aug 14.
Makker PGS, Koh CE, Solomon M, El-Hayek J, Kim B, Steffens D. The influence of postoperative morbidity on long-term quality of life outcomes following pelvic exenteration. Eur J Surg Oncol. 2024 Nov;50(11):108640. doi: 10.1016/j.ejso.2024.108640. Epub 2024 Aug 24.
Risbey CWG, Brown KGM, Solomon M, McBride K, Steffens D. Cost Analysis of Pelvic Exenteration Surgery for Advanced Pelvic Malignancy. Ann Surg Oncol. 2024 Dec;31(13):9079-9087. doi: 10.1245/s10434-024-16227-3. Epub 2024 Sep 16.
Carey S, Hogan S, Vu J, Steffens D. Nutrition interventions in prehabilitation randomised controlled trials for patients undergoing cancer surgery: too heterogeneous to digest? Support Care Cancer. 2024 Sep 21;32(10):679. doi: 10.1007/s00520-024-08863-y.
Siu A, Steffens D, Ansari N, Karunaratne S, Solanki H, Ahmadi N, Solomon M, Koh C. Evaluating patient experience and healthcare utilisation in cytoreductive surgery and hyperthermic intraperitoneal chemotherapy. Aust Health Rev. 2024 Oct;49:AH24192. doi: 10.1071/AH24192.
Steffens D, Koh C, Hirst N, Cole R, Solomon MJ, Nguyen-Lal L, Thanigasalam R, Leslie S, Ahmadi N. Prehabilitation in patients undergoing bladder cancer surgery - A systematic review and meta-analysis. Can J Urol. 2024 Oct;31(5):12004-12012.
Le M, Murphy GT, Young AF, Chan N, Constantin H, Symes M, Adie S, Guzman M. Effect of insurance type on Management of Vancouver B Periprosthetic Fractures: length of stay, discharge destination and cost implications. ANZ J Surg. 2024 Dec;94(12):2219-2224. doi: 10.1111/ans.19290. Epub 2024 Oct 29.
Alnakli AAA, Mohamedali A, Heng B, Chan C, Shin JS, Solomon M, Chapuis P, Guillemin GJ, Baker MS, Ahn SB. Protein prognostic biomarkers in stage II colorectal cancer: implications for post-operative management. BJC Rep. 2024 Feb 13;2(1):13. doi: 10.1038/s44276-024-00043-z.
Brown KGM, Morkaya J, Solomon MJ, Ng KS, White K, Sutton P, Winter DC; EvigSurg Collaborative Group; Steffens D. Priority outcomes of pelvic exenteration for rectal cancer: a patient, carer, and clinician consensus. Br J Surg. 2024 Nov 27;111(12):znae298. doi: 10.1093/bjs/znae298.
Mohamedali A, Heng B, Amirkhani A, Krishnamurthy S, Cantor D, Lee PJM, Shin JS, Solomon M, Guillemin GJ, Baker MS, Ahn SB. A Proteomic Examination of Plasma Extracellular Vesicles Across Colorectal Cancer Stages Uncovers Biological Insights That Potentially Improve Prognosis. Cancers (Basel). 2024 Dec 21;16(24):4259. doi: 10.3390/cancers16244259.
Bartyn J, Morkaya J, Karunaratne S, Chen TY, Solomon M, Koh C, Sandroussi C, Steffens D. Factors Associated with Days Alive and at Home within 30 Days (DAH30) Scores Following Surgery: A Systematic Review. Gastrointestinal Disorders. 2024 Dec 1;6(4). doi: 10.3390/gidisord6040057.
Raichurkar P, Brown K, Ansari N, Koh C, Ahmadi N, Solomon M, Moran B, Steffens D. Developing a core outcome set for cytoreductive surgery for colorectal cancer with peritoneal metastases: A mixed-method study protocol. Gastrointest Disord. 2024 Jan; 6(1):143-151. doi: 10.3390/gidisord6010010.
Jiang W, Solomon M, Karunaratne S, Beckenkamp P, Clifford K, Woodfield J, et al. Time to prioritise quality over quantity in prehabilitation trials: A literature review. EJMO. 2024 Mar;7(3):287-288. doi: 10.14744/ejmo.2023.14880.
Steffens D, Makker PGS, Ansari N, Solomon MJ, Solanki H, Moran B, Koh C.   The influence of postoperative morbidity on medium to long-term quality of life trajectories following cytoreductive surgery for peritoneal malignancy: A prospective cohort study. Surg Onc Ins. 2024 Mar; 1(1):100004. doi: /10.1016/j.soi.2023.100004.
Virk A, Treacy PJ, Zhong W, Jackson SR, Ahmadi N, Jeffery NN, Chan L, Sved P, Vasilaras A, Thanigasalam R, Leslie S. Protocol for the Robosling Trial: A Randomised Study Assessing Urinary Continence Following Robotic Radical Prostatectomy With or Without an Intraoperative Retropubic Vascularised Fascial Sling (RoboSling). Société Internationale d'Urologie Journal (SIUJ). 2024 Apr;5(2):148-159. doi: 10.3390/siuj5020024.
Makker P, Pillinger N, Ansari N, Koh C, Solomon M, Steffens D. Correlation between preoperative cardiopulmonary exercise testing and six-minute walk test, five-times sit to stand test and Short Form-36 physical component score in patients undergoing cytoreductive surgery. Surg Onc Ins. 2024 Jun;1(2):100052. doi: 10.1016/j.soi.2024.100052.
Steffens D, Koh C, Smith A, Mohan H, Carey S, Smith S, Poulton T, Patton V, White K, Laranjo L, Dieng M, Liu X, Denehy L, Wilson K, Allman-Farinelli M, Butow P, Riedel B, Morton RL, Hassett L, Li Q, Delbaere K, Hutchings O, Martin O, Dhillon H, Shailer B, Beardsworth G, Salter M, Cherry K, Rubie F, Reece L, Chan A, Shabab R, Dwyer O, Pring K, Cunningham D, Sheehan K, Iori G, Johnander R, Cole R, Hirst N, Solomon M. Virtual multimodal hub for patients undergoing major gastrointestinal cancer surgery (PRIORITY-CONNECT 2) - A pilot randomised type I hybrid effectiveness-implementation trial. Surgical Oncology Insight 2024; 1(3):Sept:100082. doi: 10.1016/j.soi.2024.100082.
Steffens D, Nott F, Koh C, Jiang W, Hirst N, Cole R, Karunaratne S, West MA, Jack S, Solomon MJ. ASO Visual Abstract: Effectiveness of Prehabilitation Modalities on Postoperative Outcomes Following Colorectal Cancer Surgery: A Systematic Review of Randomised Controlled Trials. Annals of Surgical Oncology 2024. doi: 10.1245/s10434-024-15978-3.