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Renal Medicine Research

Our Renal Medicine Department is research-active, with ongoing work in basic science, translational trials, clinical trials, cohort studies, registry studies, modelling studies, qualitative studies, meta-analyses and health economics. Our research is conducted by nurses, trainees, JMOs, advanced trainees, consultants and our PhD fellows. Our team is co-located at the Charles Perkins Centre, University of Sydney.

Our Research Team

Professor Steve Chadban Programme Lead
Professor Kate Wyburn Senior Researcher
Dr Tracey Ying Senior Researcher
Clinical Associate Professor Huiling Wu Principal Scientist
Professor David Gracey Senior Researcher
Dr John Saunders Clinical Trials Principal Investigator
Dr Paul Snelling Clinical Trials Principal Investigator
Dr Pat Lan Senior Research Fellow
Ellen Yeo Clinical Trial Coordinator
Lin Lin Clinical Trial Coordinator
Christina Gong Clinical Trial Coordinator

Selected Grants

Amount awarded Grant and project details
$1,320,000 MRFF, 2024-2027
Repurposing mTOR inhibitors to boost vaccine responses in the immunocompromised and elderly.
Investigators: Coates PT (CIA), Chadban SJ (CIB), Ying T (CIH).
$778,232 NHMRC Ideas Grant, 2021-2025
Improving Kidney Transplant Outcomes Using Normothermic Machine Perfusion
Investigators: Rogers N (CIA), Patrick E (CIB), Pleass H (CIC), Laurence J (CID), Wyburn K (CIE)
$2,237,625
(CAN)
CIHR, 2020-2024
CARSK Study: A RCT of screening for CAD while waitlisted for kidney transplantation
Associate Investigator: Chadban S
$369,182 NHMRC Partnership Grant, 2019-2024
Maximising Organ Donor offer Utility System-wide (the MODUS study)
Investigators: Webster A (CIA), Wyburn K (CIB), Morton R (CIC), McCaffery K (CID), Kelly P (CIE), Clayton P (CIF), Muscat D (CIG), De La Mata N (CIH)

Our Publications

2024

McMullen L, Drak D, Basu G, Coates PT, Goodman DJ, Graver A, Isbel N, Lim WH, Luxton G, Sciberras F, Toussaint ND, Wong G, Gracey DM. Kidney transplantation in people living with human immunodeficiency virus: An overview of the Australian experience. Nephrology (Carlton). 2024 Jan;29(1):34-38. doi: 10.1111/nep.14229. Epub 2023 Aug 21.
Gill JS, Chadban SJ. Pretransplant screening for coronary artery disease: data are required before practice change. Kidney Int. 2024 Mar;105(3):470-472. doi: 10.1016/j.kint.2023.09.026. Epub 2023 Oct 31.
Chadban S, Gill JS. How hard are the hard outcomes reported in national transplant registries? Am J Transplant. 2024 Feb;24(2):158-159. doi: 10.1016/j.ajt.2023.10.023. Epub 2023 Nov 2.
Catiwa J, Gallagher M, Talbot B, Kerr PG, Semple DJ, Roberts MA, Polkinghorne KR, Gray NA, Talaulikar G, Cass A, Kotwal S; REDUCCTION Investigators. Clinical Adjudication of Hemodialysis Catheter-Related Bloodstream Infections: Findings from the REDUCCTION Trial. Kidney360. 2024 Apr 1;5(4):550-559. doi: 10.34067/KID.0000000000000389. Epub 2024 Feb 8.
Collins MG, Fahim MA, Hawley CM, Johnson DW, Chadban SJ. Questions about the BEST-Fluids trial - Authors' reply. Lancet. 2024 Mar 9;403(10430):911-912. doi: 10.1016/S0140-6736(23)02680-6.
Lam S, Huynh A, Ying T, Sandroussi C, Gracey D, Pleass HC, Chadban S, Laurence JM. Prospective evaluation of a closed-incision negative pressure wound therapy system in kidney transplantation and its association with wound complications. Front Nephrol. 2024 Feb 27;4:1352363. doi: 10.3389/fneph.2024.1352363.
Kotton CN, Kamar N, Wojciechowski D, Eder M, Hopfer H, Randhawa P, Sester M, Comoli P, Tedesco Silva H, Knoll G, Brennan DC, Trofe-Clark J, Pape L, Axelrod D, Kiberd B, Wong G, Hirsch HH; Transplantation Society International BK Polyomavirus Consensus Group. The Second International Consensus Guidelines on the Management of BK Polyomavirus in Kidney Transplantation. Transplantation. 2024 Sep 1;108(9):1834-1866. doi: 10.1097/TP.0000000000004976. Epub 2024 Apr 12.
Gibson AA, Cox E, Schneuer FJ, Humphries J, Lee CM, Gale J, Chadban S, Gillies M, Chow CK, Colagiuri S, Nassar N. Sex differences in risk of incident microvascular and macrovascular complications: a population-based data-linkage study among 25 713 people with diabetes. J Epidemiol Community Health. 2024 Jul 10;78(8):479-486. doi: 10.1136/jech-2023-221759.
GBD 2021 Forecasting Collaborators. Burden of disease scenarios for 204 countries and territories, 2022-2050: a forecasting analysis for the Global Burden of Disease Study 2021. Lancet. 2024 May 18;403(10440):2204-2256. doi: 10.1016/S0140-6736(24)00685-8.
Mallawaarachchi AC, Fowles L, Wardrop L, Wood A, O'Shea R, Biros E, Harris T, Alexander SI, Bodek S, Boudville N, Burke J, Burnett L, Casauria S, Chadban S, Chakera A, Crafter S, Dai P, De Fazio P, Faull R, Honda A, Huntley V, Jahan S, Jayasinghe K, Jose M, Leaver A, MacShane M, Madelli EO, Nicholls K, Pawlowski R, Rangan G, Snelling P, Soraru J, Sundaram M, Tchan M, Valente G, Wallis M, Wedd L, Welland M, Whitlam J, Wilkins EJ, McCarthy H, Simons C, Quinlan C, Patel C, Stark Z, Mallett AJ. Genomic Testing in Patients with Kidney Failure of an Unknown Cause: A National Australian Study. Clin J Am Soc Nephrol. 2024 Jul 1;19(7):887-897. doi: 10.2215/CJN.0000000000000464. Epub 2024 May 3.
Singer J, Tunbridge MJ, Shi B, Perkins GB, Chai CS, Salehi T, Sim BZ, Kireta S, Johnston JK, Akerman A, Milogiannakis V, Aggarwal A, Turville S, Hissaria P, Ying T, Wu H, Grubor-Bauk B, Coates PT, Chadban SJ. Dietary Inulin to Improve SARS-CoV-2 Vaccine Response in Kidney Transplant Recipients: The RIVASTIM-Inulin Randomised Controlled Trial. Vaccines (Basel). 2024 Jun 3;12(6):608. doi: 10.3390/vaccines12060608.
Chadban S, Arıcı M, Power A, Wu MS, Mennini FS, Arango Álvarez JJ, Garcia Sanchez JJ, Barone S, Card-Gowers J, Martin A, Retat L. Projecting the economic burden of chronic kidney disease at the patient level (Inside CKD): a microsimulation modelling study. EClinicalMedicine. 2024 May 2;72:102615. doi: 10.1016/j.eclinm.2024.102615.
Jayasinghe K, Biros E, Harris T, Wood A, O'Shea R, Hill L, Fowles L, Wardrop L, Shalhoub C, Hahn D, Rangan G, Kevin L, Tchan M, Snelling P, Sandow R, Sundaram M, Chaturvedi S, Trnka P, Faull R, Poplawski NK, Huntley V, Garza D, Wallis M, Jose M, Leaver A, Trainer AH, Wilkins EJ, White S, Elbaum Y, Prawer Y, Krzesinski E, Valente G, Winship I, Ryan J, Whitlam J, Nicholls K, West K, Donaldson L, Johnstone L, Lewit-Mendes M, Kerr PG, Bodek S, Chakera A, MacShane M, Mincham C, Stackpoole E, Willis F, Soraru J, Pachter N, Bennetts B, Forbes TA, Mallawaarachchi A, Quinlan C, Patel C, McCarthy H, Goranitis I, Best S, Alexander S, Stark Z, Mallett AJ. Implementation and Evaluation of a National Multidisciplinary Kidney Genetics Clinic Network Over 10 Years. Kidney Int Rep. 2024 May 9;9(8):2372-2385. doi: 10.1016/j.ekir.2024.04.068.
Wan SS, Wyburn K, Chadban SJ, Collins MG. Balanced Electrolyte Solutions Versus 0.9% Saline for Kidney Transplantation: An Updated Systematic Review and Meta-analysis. Transplant Direct. 2024 Dec 13;11(1):e1687. doi: 10.1097/TXD.0000000000001687.
Mallawaarachchi AC, Hort Y, Wedd L, Lo K, Senum S, Toumari M, Chen W, Utsiwegota M, Mawson J, Leslie S, Laurence J, Anderson L, Snelling P, Salomon R, Rangan GK, Furlong T, Shine J, Cowley MJ. Somatic mutation in autosomal dominant polycystic kidney disease revealed by deep sequencing human kidney cysts. NPJ Genom Med. 2024 Dec 19;9(1):69. doi: 10.1038/s41525-024-00452-6.
Drak D, McManus H, Vickers T, Salerno J, Tobin M, Hughes JT, Lewis DA, Carter A, Russell D, Gunathilake M, Ali H, Guy R, O’Connor CC, Ward J, Gracey DM; on behalf of ACCESS. Renal impairment risk in Indigenous and non-Indigenous people who take HIV pre-exposure prophylaxis (PrEP): a retrospective cohort study. Sex Health. 2025;22:SH24149. doi:10.1071/SH24149.