Neuropathology Research

RPA Neuropathology performs basic and translational research into human neurological disease. As a specialist neuro-diagnostics unit we focus on tissue-based research for enhanced diagnostics as well as basic disease pathophysiology.

Our Research Team

Associate Professor Michael Buckland BSc (Med), MBBS, PhD, FRCPA, FFSc (RCPA)	Head of Department Clinical Associate Professor, School of Medical Sciences, Faculty of Medicine and Health, University of Sydney Director, Australian Sports Brain Bank and Australian Veterans Brain Bank Director, Neuropathology Tumour Tissue Bank Co-Director, MS Australia Brain Bank Co-Director, Brainstorm at RPA
Dr Laveniya Satgunaseelan MBBS, FRCPA	Staff Specialist Neuropathologist
Dr Andrew Affleck BSc MPhil PhD	Senior Hospital Scientist, Biobanking Manager, MS Australia Brain Bank Manager, Australian Sports Brain Bank and Australian Veterans Brain Bank
Dr Kim Alexander BMedSc(Hon) PhD	Head of Brain Cancer Research, Chris O'Brien Lifehouse Honorary Senior Research Officer, Sydney Local Health District Manager, Sydney Brain Tumour Bank Honorary Senior Research Fellow, University of Sydney
Danielle Davies BSc	Biobanking Scientific Officer, MS Australia Brain Bank
Dr Csilla- Ágota T'zesi PhD	Molecular Hospital Scientist, Brainstorm at RPA and Australian Sports Brain Bank
Dr Susannah Hallal BSc PhD	Postdoctoral Brain Cancer Research Fellow, Chris O'Brien Lifehouse Honorary Research Officer, Sydney Local Health District
Associate Professor Catherine Suter BSc PhD	Chief Scientist, Australian Sports Brain Bank
Ella Tu	Honours Student
Joanna New	Research Assistant

Selected Grants

Amount awarded	Grant and project details
$60,000	BrainStorm Brain Cancer Research Stipend, 2020-2023 Developing a blood test for brain cancer Investigators: Kaufman K.
$100,000	NSW Health Biospecimen Collection Grant, 2021-2024 Sydney Brain Tumour Bank and GlioNET Observational study Investigators: Varikatt W, Alexander-Kaufman K, Buckland M
$171,883	MS Australia, 2023-2025 MS Australia Brain Bank Assistant Positions. Investigator: Buckland M.

Our Publications

2023

Affleck AJ, Sachdev PS, Halliday GM. Past antihypertensive medication use is associated with lower levels of small vessel disease and lower Aβ plaque stage in the brains of older individuals. Neuropathol Appl Neurobiol. 2023 Aug;49(4):e12922. doi: 10.1111/nan.12922.

Bogumil H, Sill M, Schrimpf D, Ismer B, Blume C, Rahmanzade R, Hinz F, Cherkezov A, Banan R, Friedel D, Reuss DE, Selt F, Ecker J, Milde T, Pajtler KW, Schittenhelm J, Hench J, Frank S, Boldt HB, Kristensen BW, Scheie D, Melchior LC, Olesen V, Sehested A, Boué DR, Abdullaev Z, Satgunaseelan L, Kurth I, Seidlitz A, White CL, Ng HK, Shi ZF, Haberler C, Deckert M, Timmer M, Goldbrunner R, Tauziède-Espariat A, Varlet P, Brandner S, Alexandrescu S, Snuderl M, Aldape K, Korshunov A, Witt O, Herold-Mende C, Unterberg A, Wick W, Pfister SM, von Deimling A, Jones DTW, Sahm F, Sievers P. Glioneuronal tumor with ATRX alteration, kinase fusion and anaplastic features (GTAKA): a molecularly distinct brain tumor type with recurrent NTRK gene fusions. Acta Neuropathol. 2023 May;145(5):667-680. doi: 10.1007/s00401-023-02558-0. Epub 2023 Mar 18.

Gupta R, Strbenac D, Satgunaseelan L, Cheung VK, Narayanappa H, Ashford B, Mitchell J, Thind A, Palme CE, Ch'ng S, Low TH, Wykes J, Willet CE, Chew T, Yang J, Ranson M, Clark JR. Comparing Genomic Landscapes of Oral and Cutaneous Squamous Cell Carcinoma of the Head and Neck: Quest for Novel Diagnostic Markers. Mod Pathol. 2023 Aug;36(8):100190. doi: 10.1016/j.modpat.2023.100190. Epub 2023 Apr 18.

Henden L, Fearnley LG, Grima N, McCann EP, Dobson-Stone C, Fitzpatrick L, Friend K, Hobson L, Chan Moi Fat S, Rowe DB, D'Silva S, Kwok JB, Halliday GM, Kiernan MC, Mazumder S, Timmins HC, Zoing M, Pamphlett R, Adams L, Bahlo M, Blair IP, Williams KL. Short tandem repeat expansions in sporadic amyotrophic lateral sclerosis and frontotemporal dementia. Sci Adv. 2023 May 5;9(18):eade2044. doi: 10.1126/sciadv.ade2044. Epub 2023 May 5.

Kaivola K, Chia R, Ding J, Rasheed M, Fujita M, Menon V, Walton RL, Collins RL, Billingsley K, Brand H, Talkowski M, Zhao X, Dewan R, Stark A, Ray A, Solaiman S, Alvarez Jerez P, Malik L, Dawson TM, Rosenthal LS, Albert MS, Pletnikova O, Troncoso JC, Masellis M, Keith J, Black SE, Ferrucci L, Resnick SM, Tanaka T; American Genome Center; International LBD Genomics Consortium; International ALS/FTD Consortium; PROSPECT Consortium; Topol E, Torkamani A, Tienari P, Foroud TM, Ghetti B, Landers JE, Ryten M, Morris HR, Hardy JA, Mazzini L, D'Alfonso S, Moglia C, Calvo A, Serrano GE, Beach TG, Ferman T, Graff-Radford NR, Boeve BF, Wszolek ZK, Dickson DW, Chiò A, Bennett DA, De Jager PL, Ross OA, Dalgard CL, Gibbs JR, Traynor BJ, Scholz SW. Genome-wide structural variant analysis identifies risk loci for non-Alzheimer's dementias. Cell Genom. 2023 May 4;3(6):100316. doi: 10.1016/j.xgen.2023.100316.

Krishnan A, Wu K, Girgis L, Pamphlett R, Tomlinson S, Muthiah K. A mitochondrial cytopathy presenting with persistent troponin elevation: case report. Eur Heart J Case Rep. 2023 Apr 17;7(4):ytad132. doi: 10.1093/ehjcr/ytad132.

Lee MD, Patel SH, Mohan S, Akbari H, Bakas S, Nasrallah MP, Calabrese E, Rudie J, Villanueva-Meyer J, LaMontagne P, Marcus DS, Colen RR, Balana C, Choi YS, Badve C, Barnholtz-Sloan JS, Sloan AE, Booth TC, Palmer JD, Dicker AP, Flanders AE, Shi W, Griffith B, Poisson LM, Chakravarti A, Mahajan A, Chang S, Orringer D, Davatzikos C, Jain R; ReSPOND Consortium. Association of partial T2-FLAIR mismatch sign and isocitrate dehydrogenase mutation in WHO grade 4 gliomas: results from the ReSPOND consortium. Neuroradiology. 2023 Sep;65(9):1343-1352. doi: 10.1007/s00234-023-03196-9. Epub 2023 Jul 19.

Low JP, Satgunaseelan L, Wright D. Biallelic MGMT loss in a case of IDH-wild-type adult glioblastoma: a case for concurrent epigenomic and molecular karyotype testing. Pathology. 2023 Jun;55(4):551-554. doi: 10.1016/j.pathol.2022.10.015. Epub 2023 Jan 20.

Pamphlett R, Bishop DP. The toxic metal hypothesis for neurological disorders. Front Neurol. 2023 Jun 23;14:1173779. doi: 10.3389/fneur.2023.1173779.

Pamphlett R, Buckland ME, Bishop DP. Potentially toxic elements in the brains of people with multiple sclerosis. Sci Rep. 2023 Jan 12;13(1):655. doi: 10.1038/s41598-022-27169-9.

Stewart W, Buckland ME, Abdolmohammadi B, Affleck AJ, Alvarez VE, Gilchrist S, Huber BR, Lee EB, Lyall DM, Nowinski CJ, Russell ER, Stein TD, Suter CM, McKee AC. Risk of chronic traumatic encephalopathy in rugby union is associated with length of playing career. Acta Neuropathol. 2023 Dec;146(6):829-832. doi: 10.1007/s00401-023-02644-3. Epub 2023 Oct 24.

Suter CM, Affleck AJ, Pearce AJ, Junckerstorff R, Lee M, Buckland ME. Chronic traumatic encephalopathy in a female ex-professional Australian rules footballer. Acta Neuropathol. 2023 Sep;146(3):547-549. doi: 10.1007/s00401-023-02610-z. Epub 2023 Jun 30.

Tűzesi Á, Hallal S, Satgunaseelan L, Buckland ME, Alexander KL. Understanding the Epitranscriptome for Avant-Garde Brain Tumour Diagnostics. Cancers (Basel). 2023 Feb 15;15(4):1232. doi: 10.3390/cancers15041232.

Watson CJG, Lawlor M, Sy J, Krishnaswamy M, Buckland ME, Brennan JW, Satgunaseelan L. Anaplasia and age of onset in desmoplastic infantile ganglioglioma: Case report and review of the literature. Pediatr Blood Cancer. 2023 Jan;70(1):e29808. doi: 10.1002/pbc.29808. Epub 2022 Jun 7.

Yuile A, Satgunaseelan L, Wei JQ, Rodriguez M, Back M, Pavlakis N, Hudson A, Kastelan M, Wheeler HR, Lee A. CDKN2A/B Homozygous Deletions in Astrocytomas: A Literature Review. Curr Issues Mol Biol. 2023 Jun 22;45(7):5276-5292. doi: 10.3390/cimb45070335.

2022

Hallal S, Tűzesi Á, Grau GE, Buckland ME, Alexander KL. Understanding the extracellular vesicle surface for clinical molecular biology. J Extracell Vesicles. 2022 Oct;11(10):e12260. doi: 10.1002/jev2.12260.

Buckland ME, Affleck AJ, Pearce AJ, Suter CM. Chronic Traumatic Encephalopathy as a Preventable Environmental Disease. Front Neurol. 2022 Jun 13;13:880905. doi: 10.3389/fneur.2022.880905.

Nowinski CJ, Bureau SC, Buckland ME, Curtis MA, Daneshvar DH, Faull RLM, Grinberg LT, Hill-Yardin EL, Murray HC, Pearce AJ, Suter CM, White AJ, Finkel AM, Cantu RC. Applying the Bradford Hill Criteria for Causation to Repetitive Head Impacts and Chronic Traumatic Encephalopathy. Front Neurol. 2022 Jul 22;13:938163. doi: 10.3389/fneur.2022.938163.

Suter CM, Affleck AJ, Lee M, Davies D, Burns AL, Sy J, I'Ons B, Buckland ME. Chronic Traumatic Encephalopathy in a Routine Neuropathology Service in Australia. J Neuropathol Exp Neurol. 2022 Sep 19;81(10):790-795. doi: 10.1093/jnen/nlac071.

Butler MLMD, Dixon E, Stein TD, Alvarez VE, Huber B, Buckland ME, McKee AC, Cherry JD. Tau Pathology in Chronic Traumatic Encephalopathy is Primarily Neuronal. J Neuropathol Exp Neurol. 2022 Sep 19;81(10):773-780. doi: 10.1093/jnen/nlac065. Erratum in: J Neuropathol Exp Neurol. 2023 Mar 20;82(4):373.

Suter CM, Affleck AJ, Lee M, Pearce AJ, Iles LE, Buckland ME. Chronic traumatic encephalopathy in Australia: the first three years of the Australian Sports Brain Bank. Med J Aust. 2022 Jun 6;216(10):530-531. doi: 10.5694/mja2.51420. Epub 2022 Feb 10.

Yuile A, Satgunaseelan L, Wei J, Kastelan M, Back MF, Lee M, Wei H, Buckland ME, Lee A, Wheeler HR. Implications of Concurrent IDH1 and IDH2 Mutations on Survival in Glioma-A Case Report and Systematic Review. Curr Issues Mol Biol. 2022 Oct 21;44(10):5117-5125. doi: 10.3390/cimb44100348.

Goire N, Edwards L, Thomas P, Bhaskar SMM, Cordato D, Buckland ME, Beran RG. Creutzfeldt-Jakob Disease in South West Sydney 2014-2020: An Unusually High Incidence of a Rare Disease. Neuroepidemiology. 2022;56(1):59-65. doi: 10.1159/000520736. Epub 2021 Nov 11.

Lasocki A, Buckland ME, Drummond KJ, Wei H, Xie J, Christie M, Neal A, Gaillard F. Conventional MRI features can predict the molecular subtype of adult grade 2-3 intracranial diffuse gliomas. Neuroradiology. 2022 Dec;64(12):2295-2305. doi: 10.1007/s00234-022-02975-0. Epub 2022 May 24.

Alzoubi I, Bao G, Zhang R, Loh C, Zheng Y, Cherepanoff S, Gracie G, Lee M, Kuligowski M, Alexander KL, Buckland ME, Wang X, Graeber MB. An Open-Source AI Framework for the Analysis of Single Cells in Whole-Slide Images with a Note on CD276 in Glioblastoma. Cancers (Basel). 2022 Jul 15;14(14):3441. doi: 10.3390/cancers14143441.

Spiteri AG, Wishart CL, Pamphlett R, Locatelli G, King NJC. Microglia and monocytes in inflammatory CNS disease: integrating phenotype and function. Acta Neuropathol. 2022 Feb;143(2):179-224. doi: 10.1007/s00401-021-02384-2. Epub 2021 Dec 1.

Freydenzon A, Nabais MF, Lin T, Williams KL, Wallace L, Henders AK, Blair IP, Wray NR, Pamphlett R, McRae AF. Association between DNA methylation variability and self-reported exposure to heavy metals. Sci Rep. 2022 Jun 22;12(1):10582. doi: 10.1038/s41598-022-13892-w.

Grima N, Henden L, Fearnley LG, Rowe DB, D'Silva S, Pamphlett R, Adams L, Kiernan MC, Mazumder S, Timmins HC, Zoing M, Bahlo M, Blair IP, Williams KL. NEK1 and STMN2 short tandem repeat lengths are not associated with Australian amyotrophic lateral sclerosis risk. Neurobiol Aging. 2022 Aug;116:92-95. doi: 10.1016/j.neurobiolaging.2022.04.012. Epub 2022 May 22.

Restuadi R, Garton FC, Benyamin B, Lin T, Williams KL, Vinkhuyzen A, van Rheenen W, Zhu Z, Laing NG, Mather KA, Sachdev PS, Ngo ST, Steyn FJ, Wallace L, Henders AK, Visscher PM, Needham M, Mathers S, Nicholson G, Rowe DB, Henderson RD, McCombe PA, Pamphlett R, Blair IP, Wray NR, McRae AF. Polygenic risk score analysis for amyotrophic lateral sclerosis leveraging cognitive performance, educational attainment and schizophrenia. Eur J Hum Genet. 2022 May;30(5):532-539. doi: 10.1038/s41431-021-00885-y. Epub 2021 Apr 27.

van Rheenen W, van der Spek RAA, Bakker MK, van Vugt JJFA, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker AM, Gawor K, Westeneng HJ, Tazelaar GHP, van Eijk KR, Kooyman M, Byrne RP, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith BN, Gromicho M, Chandran S, Pal S, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Sendtner M, Meyer T, Başak N, van der Kooi AJ, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D'Alfonso S, Sorarù G, Siciliano G, Filosto M, Padovani A, Chiò A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh RH, Bell S, Vourc'h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina JS, Assialioui A, Rojas-García R, Dion PA, Ross JP, Ludolph AC, Weishaupt JH, Brenner D, Freischmidt A, Bensimon G, Brice A, Durr A, Payan CAM, Saker-Delye S, Wood NW, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman DC, Olsen CM, Uitterlinden AG, Hofman A, Rietschel M, Cichon S, Nöthen MM, Amouyel P; SLALOM Consortium; PARALS Consortium; SLAGEN Consortium; SLAP Consortium; Traynor BJ, Singleton AB, Mitne Neto M, Cauchi RJ, Ophoff RA, Wiedau-Pazos M, Lomen-Hoerth C, van Deerlin VM, Grosskreutz J, Roediger A, Gaur N, Jörk A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte OW, Steinbach R, Hübner CA, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glavač M, Glavač D, Stević Z, Drory V, Povedano M, Blair IP, Kiernan MC, Benyamin B, Henderson RD, Furlong S, Mathers S, McCombe PA, Needham M, Ngo ST, Nicholson GA, Pamphlett R, Rowe DB, Steyn FJ, Williams KL, Mather KA, Sachdev PS, Henders AK, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau GA, Silani V, Curtis CJ, Breen G, Glass JD, Brown RH Jr, Landers JE, Shaw CE, Andersen PM, Groen EJN, van Es MA, Pasterkamp RJ, Fan D, Garton FC, McRae AF, Davey Smith G, Gaunt TR, Eberle MA, Mill J, McLaughlin RL, Hardiman O, Kenna KP, Wray NR, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg LH, Veldink JH. Author Correction: Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet. 2022 Mar;54(3):361. doi: 10.1038/s41588-022-01020-3. Erratum for: Nat Genet. 2021 Dec;53(12):1636-1648.

Pamphlett R, Bishop DP. Mercury is present in neurons and oligodendrocytes in regions of the brain affected by Parkinson's disease and co-localises with Lewy bodies. PLoS One. 2022 Jan 11;17(1):e0262464. doi: 10.1371/journal.pone.0262464.

Luu W, Sy J, Luu Q. Necrotising autoimmune myopathy: a differential diagnosis for deranged liver function tests. Med J Aust. 2022 Jul 4;217(1):20-22. doi: 10.5694/mja2.51609. Epub 2022 Jun 13.

Yuile A, Khasraw M, Low JT, Walsh KM, Lipp E, Sy J, Satgunaseelan L, Kastelan MA, De Silva M, Lee A, Wheeler H. Patterns of care in adult histone mutant gliomas: Results of an international survey. Neurooncol Pract. 2022 Jun 5;9(6):520-525. doi: 10.1093/nop/npac047.

Horak P, Griffith M, Danos AM, Pitel BA, Madhavan S, Liu X, Chow C, Williams H, Carmody L, Barrow-Laing L, Rieke D, Kreutzfeldt S, Stenzinger A, Tamborero D, Benary M, Rajagopal PS, Ida CM, Lesmana H, Satgunaseelan L, Merker JD, Tolstorukov MY, Campregher PV, Warner JL, Rao S, Natesan M, Shen H, Venstrom J, Roy S, Tao K, Kanagal-Shamanna R, Xu X, Ritter DI, Pagel K, Krysiak K, Dubuc A, Akkari YM, Li XS, Lee J, King I, Raca G, Wagner AH, Li MM, Plon SE, Kulkarni S, Griffith OL, Chakravarty D, Sonkin D. Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC). Genet Med. 2022 May;24(5):986-998. doi: 10.1016/j.gim.2022.01.001. Epub 2022 Jan 29. Erratum in: Genet Med. 2022 Sep;24(9):1991.

Fielder T, Butler J, Tierney G, Holmes M, Lam KY, Satgunaseelan L, Colebatch AJ, Mahar A, Gupta R, O'Toole S, Cooper WA. ROS1 rearrangements in lung adenocarcinomas are defined by diffuse strong immunohistochemical expression of ROS1. Pathology. 2022 Jun;54(4):399-403. doi: 10.1016/j.pathol.2021.07.012. Epub 2021 Oct 25.

Gorolay V, Martens D, Satgunaseelan L, Van Camp L, Winkler G. Hemorrhagic Meningitis Due to Varicella-Zoster Virus: A Case Report With Clinical, Cytologic, and Radiologic Correlation. Cureus. 2022 Nov 5;14(11):e31113. doi: 10.7759/cureus.31113.

Horak P, Griffith M, Danos AM, Pitel BA, Madhavan S, Liu X, Chow C, Williams H, Carmody L, Barrow-Laing L, Rieke D, Kreutzfeldt S, Stenzinger A, Tamborero D, Benary M, Rajagopal PS, Ida CM, Lesmana H, Satgunaseelan L, Merker JD, Tolstorukov MY, Campregher PV, Warner JL, Rao S, Natesan M, Shen H, Venstrom J, Roy S, Tao K, Kanagal-Shamanna R, Xu X, Ritter DI, Pagel K, Krysiak K, Dubuc A, Akkari YM, Li XS, Lee J, King I, Raca G, Wagner AH, Li MM, Plon SE, Kulkarni S, Griffith OL, Chakravarty D, Sonkin D. Standards for the classification of pathogenicity of somatic variants in cancer (oncogenicity): Joint recommendations of Clinical Genome Resource (ClinGen), Cancer Genomics Consortium (CGC), and Variant Interpretation for Cancer Consortium (VICC). Genet Med. 2022 Sep;24(9):1991. doi: 10.1016/j.gim.2022.07.001. Erratum for: Genet Med. 2022 May;24(5):986-998.

Satgunaseelan L, Strbenac D, Tadi S, Nguyen K, Wykes J, Palme CE, Low TH, Yang JYH, Clark JR, Gupta R. Viral Integration Plays a Minor Role in the Development and Prognostication of Oral Squamous Cell Carcinoma. Cancers (Basel). 2022 Oct 24;14(21):5213. doi: 10.3390/cancers14215213.

Jackett LA, Satgunaseelan L, Roper E, Lo SN, Thompson JF, Scolyer RA. Residual melanoma in wide local excision specimens after 'complete' excision of primary cutaneous in situ and invasive melanomas. Pathology. 2022 Feb;54(1):71-78. doi: 10.1016/j.pathol.2021.05.094. Epub 2021 Aug 13.

Satgunaseelan L, Strbenac D, Willet C, Chew T, Sadsad R, Wykes J, Low TH, Cooper WA, Lee CS, Palme CE, Yang JYH, Clark JR, Gupta R. Whole genome duplication in oral squamous cell carcinoma in patients younger than 50 years: implications for prognosis and adverse clinicopathological factors. Genes Chromosomes Cancer. 2022 Sep;61(9):561-571. doi: 10.1002/gcc.23076. Epub 2022 Jun 24.

Yabe TE, King K, Russell S, Satgunaseelan L, Gupta R, Chen J, Ashford B. "MYH9 mutation and squamous cell cancer of the tongue in a young adult: a novel case report". Diagn Pathol. 2022 Feb 6;17(1):23. doi: 10.1186/s13000-022-01210-x.

Griffin CP, Paul CL, Alexander KL, Walker MM, Hondermarck H, Lynam J. Postmortem brain donations vs premortem surgical resections for glioblastoma research: viewing the matter as a whole. Neurooncol Adv. 2021 Nov 18;4(1):vdab168. doi: 10.1093/noajnl/vdab168.

Reher R, Aron AT, Fajtová P, Stincone P, Wagner B, Pérez-Lorente AI, Liu C, Shalom IYB, Bittremieux W, Wang M, Jeong K, Matos-Hernandez ML, Alexander KL, Caro-Diaz EJ, Naman CB, Scanlan JHW, Hochban PMM, Diederich WE, Molina-Santiago C, Romero D, Selim KA, Sass P, Brötz-Oesterhelt H, Hughes CC, Dorrestein PC, O'Donoghue AJ, Gerwick WH, Petras D. Native metabolomics identifies the rivulariapeptolide family of protease inhibitors. Nat Commun. 2022 Aug 8;13(1):4619. doi: 10.1038/s41467-022-32016-6.

2021

Abey, A., Davies, D., Goldsbury, C., Buckland, M., Valenzuela, M., Duncan, T. Distribution of tau hyperphosphorylation in canine dementia resembles early Alzheimer's disease and other tauopathies. Brain Pathology 2021;31(1):144-62.

Bao, G., Wang, X., Xu, R., Loh, C., Adeyinka, O.D., Pieris, D.A., Cherepanoff, S., Gracie, G., Lee, M., McDonald, K.L., Nowak, A.K., Banati, R., Buckland, M.E., Graeber, M.B. Pathofusion: An open?source AI framework for recognition of pathomorphological features and mapping of immunohistochemical data. Cancers 2021;13(4):1-15.

Chan Moi Fat S, McCann EP, Williams KL, Henden L, Twine NA, Bauer DC, Pamphlett R, Kiernan MC, Rowe DB, Nicholson GA, Fifita JA, Blair IP Genetic analysis of GLT8D1 and ARPP21 in Australian familial and sporadic amyotrophic lateral sclerosis. Neurobiol Aging. 2021;101: 297 e299-297 e211.

Cheung, V.K.Y., Buckland, M.E., Wei, G., Lee, M., Sy, J. Next generation sequencing impacts the classification and management of primary brain tumours. Pathology 2021;53(6):780-2.

Debinski, C., Goergen, S., McLean, C., Buckland, M.E., Kumar, B., Tiller, G., Cole, T., Ojaimi, S., Fahey, M. Exploring the Intersection of Isolated-CNS Hemophagocytic Lymphohistiocytosis and Pediatric Chronic Lymphocytic Inflammation With Pontine Perivascular Enhancement Responsive to Steroids. Journal of Child Neurology 2021;36(11):935-42.

Fifita JA, Chan Moi Fat S, McCann EP, Williams KL, Twine NA, Bauer DC, Rowe DB, Pamphlett R, Kiernan MC, Tan VX, Blair IP, Guillemin GJ Genetic Analysis of Tryptophan Metabolism Genes in Sporadic Amyotrophic Lateral Sclerosis. Front Immunol. 2021;12: 701550.

Goire, N., Buckland, M., Cuganesan, R., Saleem, S., Lea, V., Beran, R.G. A diagnostic dilemma of white matter lesions and cerebral oedema without identifiable cause-A neurological conundrum. Brain Sciences 2021;11(9):1238.

Johnson JO, Chia R, Miller DE, Li R, Kumaran R, Abramzon Y, Alahmady N, Renton AE, Topp SD, Gibbs JR, Cookson MR, Sabir MS, Dalgard CL, Troakes C, Jones AR, Shatunov A, Iacoangeli A, Al Khleifat A, Ticozzi N, Silani V, Gellera C, Blair IP, Dobson-Stone C, Kwok JB, Bonkowski ES, Palvadeau R, Tienari PJ, Morrison KE, Shaw PJ, Al-Chalabi A, Brown RH, Jr., Calvo A, Mora G, Al-Saif H, Gotkine M, Leigh F, Chang IJ, Perlman SJ, Glass I, Scott AI, Shaw CE, Basak AN, Landers JE, Chio A, Crawford TO, Smith BN, Traynor BJ, Consortium FS, American Genome C, International ALSGC, Consortium I, Smith BN, Ticozzi N, Fallini C, Gkazi AS, Topp SD, Scotter EL, Kenna KP, Keagle P, Tiloca C, Vance C, Troakes C, Colombrita C, King A, Pensato V, Castellotti B, Baas F, Ten Asbroek A, McKenna-Yasek D, McLaughlin RL, Polak M, Asress S, Esteban-Perez J, Stevic Z, D'Alfonso S, Mazzini L, Comi GP, Del Bo R, Ceroni M, Gagliardi S, Querin G, Bertolin C, van Rheenen W, Rademakers R, van Blitterswijk M, Lauria G, Duga S, Corti S, Cereda C, Corrado L, Soraru G, Williams KL, Nicholson GA, Blair IP, Leblond-Manry C, Rouleau GA, Hardiman O, Morrison KE, Veldink JH, van den Berg LH, Al-Chalabi A, Pall H, Shaw PJ, Turner MR, Talbot K, Taroni F, Garcia-Redondo A, Wu Z, Glass JD, Gellera C, Ratti A, Brown RH, Jr., Silani V, Shaw CE, Landers JE, Dalgard CL, Adeleye A, Soltis AR, Alba C, Viollet C, Bacikova D, Hupalo DN, Sukumar G, Pollard HB, Wilkerson MD, Martinez EM, Abramzon Y, Ahmed S, Arepalli S, Baloh RH, Bowser R, Brady CB, Brice A, Broach J, Campbell RH, Camu W, Chia R, Cooper-Knock J, Ding J, Drepper C, Drory VE, Dunckley TL, Eicher JD, England BK, Faghri F, Feldman E, Floeter MK, Fratta P, Geiger JT, Gerhard G, Gibbs JR, Gibson SB, Glass JD, Hardy J, Harms MB, Heiman-Patterson TD, Hernandez DG, Jansson L, Kirby J, Kowall NW, Laaksovirta H, Landeck N, Landi F, Le Ber I, Lumbroso S, MacGowan DJL, Maragakis NJ, Mora G, Mouzat K, Murphy NA, Myllykangas L, Nalls MA, Orrell RW, Ostrow LW, Pamphlett R, Pickering-Brown S, Pioro EP, Pletnikova O, Pliner HA, Pulst SM, Ravits JM, Renton AE, Rivera A, Robberecht W, Rogaeva E, Rollinson S, Rothstein JD, Scholz SW, Sendtner M, Shaw PJ, Sidle KC, Simmons Z, Singleton AB, Smith N, Stone DJ, Tienari PJ, Troncoso JC, Valori M, Van Damme P, Van Deerlin VM, Van Den Bosch L, Zinman L, Landers JE, Chio A, Traynor BJ, Angelocola SM, Ausiello FP, Barberis M, Bartolomei I, Battistini S, Bersano E, Bisogni G, Borghero G, Brunetti M, Cabona C, Calvo A, Canale F, Canosa A, Cantisani TA, Capasso M, Caponnetto C, Cardinali P, Carrera P, Casale F, Chio A, Colletti T, Conforti FL, Conte A, Conti E, Corbo M, Cuccu S, Dalla Bella E, D'Errico E, DeMarco G, Dubbioso R, Ferrarese C, Ferraro PM, Filippi M, Fini N, Floris G, Fuda G, Gallone S, Gianferrari G, Giannini F, Grassano M, Greco L, Iazzolino B, Introna A, La Bella V, Lattante S, Lauria G, Liguori R, Logroscino G, Logullo FO, Lunetta C, Mandich P, Mandrioli J, Manera U, Manganelli F, Marangi G, Marinou K, Marrosu MG, Martinelli I, Messina S, Moglia C, Mora G, Mosca L, Murru MR, Origone P, Passaniti C, Petrelli C, Petrucci A, Pozzi S, Pugliatti M, Quattrini A, Ricci C, Riolo G, Riva N, Russo M, Sabatelli M, Salamone P, Salivetto M, Salvi F, Santarelli M, Sbaiz L, Sideri R, Simone I, Simonini C, Spataro R, Tanel R, Tedeschi G, Ticca A, Torriello A, Tranquilli S, Tremolizzo L, Trojsi F, Vasta R, Vacchiano V, Vita G, Volanti P, Zollino M, Zucchi E Association of Variants in the SPTLC1 Gene With Juvenile Amyotrophic Lateral Sclerosis. JAMA Neurol. 2021;78: 1236-1248.

Kong, B.Y., Sim, H.-W., Nowak, A.K., Yip, S., Barnes, E.H., Day, B.W., Buckland, M.E., Verhaak, R., Johns, T., Robinson, C., Thomas, M.A., Giardina, T., Lwin, Z., Scott, A.M., Parkinson, J., Jeffree, R., Lourenco, R.D.A., Hovey, E.J., Cher, L.M., Kichendasse, G., Khasraw, M., Hall, M., Tu, E., Amanuel, B., Koh, E.-S., Gan, H.K. LUMOS - Low and Intermediate Grade Glioma Umbrella Study of Molecular Guided TherapieS at relapse: Protocol for a pilot study. BMJ Open 2021;11(12):e054075.

Nabais MF, Laws SM, Lin T, Vallerga CL, Armstrong NJ, Blair IP, Kwok JB, Mather KA, Mellick GD, Sachdev PS, Wallace L, Henders AK, Zwamborn RAJ, Hop PJ, Lunnon K, Pishva E, Roubroeks JAY, Soininen H, Tsolaki M, Mecocci P, Lovestone S, Kloszewska I, Vellas B, Australian Imaging B, Lifestyle s, Alzheimer's Disease Neuroimaging I, Furlong S, Garton FC, Henderson RD, Mathers S, McCombe PA, Needham M, Ngo ST, Nicholson G, Pamphlett R, Rowe DB, Steyn FJ, Williams KL, Anderson TJ, Bentley SR, Dalrymple-Alford J, Fowder J, Gratten J, Halliday G, Hickie IB, Kennedy M, Lewis SJG, Montgomery GW, Pearson J, Pitcher TL, Silburn P, Zhang F, Visscher PM, Yang J, Stevenson AJ, Hillary RF, Marioni RE, Harris SE, Deary IJ, Jones AR, Shatunov A, Iacoangeli A, van Rheenen W, van den Berg LH, Shaw PJ, Shaw CE, Morrison KE, Al-Chalabi A, Veldink JH, Hannon E, Mill J, Wray NR, McRae AF Meta-analysis of genome-wide DNA methylation identifies shared associations across neurodegenerative disorders. Genome Biol. 2021;22: 90.

Oh LJ, Satgunaseelan L, Asher R, Veness M, Smee R, Goldstein D, Gopalakrishna Iyer N, Balasubramanian D, Low H, Palme CE, Gupta R, Clark JR. Young age is not a predictor of disease specific survival in oral cancer: A multi-institutional study. Oral Oncol. 2021 Apr;115:105162. doi: 10.1016/j.oraloncology.2020.105162. Epub 2021 Feb 3. PMID: 33548861.

Pamphlett R The prevalence of inorganic mercury in human cells increases during aging but decreases in the very old. Sci Rep. 2021;11: 16714.

Pamphlett R, Doble PA, Bishop DP Mercury in the human thyroid gland: Potential implications for thyroid cancer, autoimmune thyroiditis, and hypothyroidism. PLoS One. 2021;16: e0246748.

Pamphlett R, Doble PA, Bishop DP The Prevalence of Inorganic Mercury in Human Kidneys Suggests a Role for Toxic Metals in Essential Hypertension. Toxics. 2021;9.

Pamphlett R, Kum Jew S, Doble PA, Bishop DP Mercury in the human adrenal medulla could contribute to increased plasma noradrenaline in aging. Sci Rep. 2021;11: 2961.

Pearce, A.J., Kidgell, D.J., Tommerdahl, M.A., Frazer, A.K., Rist, B., Mobbs, R., Batchelor, J., Buckland, M.E. Chronic Neurophysiological Effects of Repeated Head Trauma in Retired Australian Male Sport Athletes. Frontiers in Neurology 2021;12:633320.

Satgunaseelan L, Porazinski S, Strbenac D, Istadi A, Willet C, Chew T, Sadsad R, Palme CE, Lee JH, Boyer M, Yang JYH, Clark JR, Pajic M, Gupta R. Oral Squamous Cell Carcinoma in Young Patients Show Higher Rates of EGFR Amplification: Implications for Novel Personalized Therapy. Front Oncol. 2021 Nov 29;11:750852. doi: 10.3389/fonc.2021.750852.

Sim, H.-W., Mcdonald, K.L., Lwin, Z., Barnes, E.H., Rosenthal, M., Foote, M.C., Koh, E.-S., Back, M., Wheeler, H., Sulman, E.P., Buckland, M.E., Fisher, L., Leonard, R., Hall, M., Ashley, D.M., Yip, S., Simes, J., Khasraw, M. A randomized phase II trial of veliparib, radiotherapy, and temozolomide in patients with unmethylated MGMT glioblastoma: The VERTU study. Neuro-Oncology 2021;23(10):1736-49.

van Rheenen W, van der Spek RAA, Bakker MK, van Vugt J, Hop PJ, Zwamborn RAJ, de Klein N, Westra HJ, Bakker OB, Deelen P, Shireby G, Hannon E, Moisse M, Baird D, Restuadi R, Dolzhenko E, Dekker AM, Gawor K, Westeneng HJ, Tazelaar GHP, van Eijk KR, Kooyman M, Byrne RP, Doherty M, Heverin M, Al Khleifat A, Iacoangeli A, Shatunov A, Ticozzi N, Cooper-Knock J, Smith BN, Gromicho M, Chandran S, Pal S, Morrison KE, Shaw PJ, Hardy J, Orrell RW, Sendtner M, Meyer T, Basak N, van der Kooi AJ, Ratti A, Fogh I, Gellera C, Lauria G, Corti S, Cereda C, Sproviero D, D'Alfonso S, Soraru G, Siciliano G, Filosto M, Padovani A, Chio A, Calvo A, Moglia C, Brunetti M, Canosa A, Grassano M, Beghi E, Pupillo E, Logroscino G, Nefussy B, Osmanovic A, Nordin A, Lerner Y, Zabari M, Gotkine M, Baloh RH, Bell S, Vourc'h P, Corcia P, Couratier P, Millecamps S, Meininger V, Salachas F, Mora Pardina JS, Assialioui A, Rojas-Garcia R, Dion PA, Ross JP, Ludolph AC, Weishaupt JH, Brenner D, Freischmidt A, Bensimon G, Brice A, Durr A, Payan CAM, Saker-Delye S, Wood NW, Topp S, Rademakers R, Tittmann L, Lieb W, Franke A, Ripke S, Braun A, Kraft J, Whiteman DC, Olsen CM, Uitterlinden AG, Hofman A, Rietschel M, Cichon S, Nothen MM, Amouyel P, Consortium S, Consortium P, Consortium S, Consortium S, Traynor BJ, Singleton AB, Mitne Neto M, Cauchi RJ, Ophoff RA, Wiedau-Pazos M, Lomen-Hoerth C, van Deerlin VM, Grosskreutz J, Roediger A, Gaur N, Jork A, Barthel T, Theele E, Ilse B, Stubendorff B, Witte OW, Steinbach R, Hubner CA, Graff C, Brylev L, Fominykh V, Demeshonok V, Ataulina A, Rogelj B, Koritnik B, Zidar J, Ravnik-Glavac M, Glavac D, Stevic Z, Drory V, Povedano M, Blair IP, Kiernan MC, Benyamin B, Henderson RD, Furlong S, Mathers S, McCombe PA, Needham M, Ngo ST, Nicholson GA, Pamphlett R, Rowe DB, Steyn FJ, Williams KL, Mather KA, Sachdev PS, Henders AK, Wallace L, de Carvalho M, Pinto S, Petri S, Weber M, Rouleau GA, Silani V, Curtis CJ, Breen G, Glass JD, Brown RH, Jr., Landers JE, Shaw CE, Andersen PM, Groen EJN, van Es MA, Pasterkamp RJ, Fan D, Garton FC, McRae AF, Davey Smith G, Gaunt TR, Eberle MA, Mill J, McLaughlin RL, Hardiman O, Kenna KP, Wray NR, Tsai E, Runz H, Franke L, Al-Chalabi A, Van Damme P, van den Berg LH, Veldink JH Common and rare variant association analyses in amyotrophic lateral sclerosis identify 15 risk loci with distinct genetic architectures and neuron-specific biology. Nat Genet. 2021;53: 1636-1648.

2020

Azimi A, Kaufman KL, Kim J, Ali M, Mann GJ, Fernandez-Penas P. Proteomics: An emerging approach for the diagnosis and classification of cutaneous squamous cell carcinoma and its precursors. J Dermatol Sci 2020;99(1):9-16.

Azimi A, Yang P, Ali M, Howard V, Mann GJ, Kaufman KL, Fernandez-Penas P. Data independent acquisition proteomic analysis can discriminate between actinic keratosis, bowen's disease, and cutaneous squamous cell carcinoma. J Invest Dermatol 2020;140(1):212,222.e11.

Cignarella F, Filipello F, Bollman B, Cantoni C, Locca A, Mikesell R, Manis M, Ibrahim A, Deng L, Benitez B, Cruchaga C, Licastro D, Mihindukulasuriya K, Harari O, Buckland M, et al. TREM2 activation on microglia promotes myelin debris clearance and remyelination in a model of multiple sclerosis. Acta Neuropathologica, 2020;140(4):513-534.

De Sousa S, Toubia J, Hardy T, Feng J, Wang P, Schreiber A, Geoghegan J, Hall R, Rawlings L, Buckland M, et al. Aberrant Splicing of SDHC in Families With Unexplained Succinate Dehydrogenase-Deficient Paragangliomas. Journal of the Endocrine Society, 2020;4(12).

Ebrahimkhani S, Beadnall HN, Wang C, Suter CM, Barnett MH, Buckland ME, Vafaee F. Serum exosome MicroRNAs predict multiple sclerosis disease activity after fingolimod treatment. Mol Neurobiol 2020;57(2):1245-58.

Fish C, Sy J, Wong J. High mitotic activity in a capillary hemangioma of the cauda equina: Case report and review of the literature. Clinical Neuropathology, 2020;39(5), 135-138. doi:10.5414/NP301227

Gedye C, Sachchithananthan M, Leonard R, Jeffree RL, Jeffree RL, Buckland ME, et al. Driving innovation through collaboration: Development of clinical annotation datasets for brain cancer biobanking. Neuro-Oncol Pract 2020;7(1):31-7.

Hallal S, Azimi A, Wei H, Ho N, Lee M, Sim H, Sy J, Shivalingam B, Buckland M, Alexander-Kaufman K. A Comprehensive Proteomic SWATH-MS Workflow for Profiling Blood Extracellular Vesicles: A New Avenue for Glioma Tumour Surveillance. International Journal of Molecular Sciences, 2020;21(13):4754.

Hallal S, Ebrahim Khani S, Wei H, Lee M, Sim H, Sy J, Shivalingam B, Buckland M, Alexander-Kaufman K. Deep Sequencing of Small RNAs from Neurosurgical Extracellular Vesicles Substantiates miR-486-3p as a Circulating Biomarker that Distinguishes Glioblastoma from Lower-Grade Astrocytoma Patients. International Journal of Molecular Sciences, 2020;21(14):4954.

Iacoangeli A, Lin T, Al Khleifat A, Jones A, Opie-Martin S, Coleman J, Shatunov A, Sproviero W, Williams K, Garton F, Restuadi R, Henders A, Mather K, Needham M, Mathers S, Nicholson G, Rowe D, Henderson R, McCombe P, Pamphlett R, et al. Genome-wide Meta-analysis Finds the ACSL5-ZDHHC6 Locus Is Associated with ALS and Links Weight Loss to the Disease Genetics. Cell Reports, 2020;33: 108323. doi: 10.1016/j.celrep.2020.108323

Itchins M, Lau B, Hudson A, Westman H, Xia C, Hayes S, Howell V, Rodriguez M, Cooper W, Wei H, Buckland M, et al. ALK ‐Rearranged Non‐Small Cell Lung Cancer in 2020: Real‐World Triumphs in an Era of Multigeneration ALK‐Inhibitor Sequencing Informed by Drug Resistance Profiling. The Oncologist, 2020;25(8):641-649.

McCann EP, Henden L, Fifita JA, Zhang KY, Grima N, Bauer DC, et al. Evidence for polygenic and oligogenic basis of Australian sporadic amyotrophic lateral sclerosis. J Med Genet. 2020. doi: 10.1136/jmedgenet-2020-106866.

Nabais MF, Lin T, Benyamin B, Williams KL, Garton FC, Vinkhuyzen AAE, et al. Significant out-of-sample classification from methylation profile scoring for amyotrophic lateral sclerosis. NPJ Genom Med. 2020;5: 10. doi: 10.1038/s41525-020-0118-3.

Pamphlett R, Cherepanoff S, Too LK, Kum Jew S, Doble PA, Bishop DP. The distribution of toxic metals in the human retina and optic nerve head: Implications for age-related macular degeneration. PLoS One. 2020;15: e0241054. doi: 10.1371/journal.pone.0241054.

Pamphlett R, Colebatch AJ, Doble PA, Bishop DP. Mercury in Pancreatic Cells of People with and without Pancreatic Cancer. Int J Environ Res Public Health. 2020;17. doi: 10.3390/ijerph17238990.

Pamphlett R, Kum Jew S, Doble PA, Bishop DP. Elemental imaging shows mercury in cells of the human lateral and medial geniculate nuclei. PLoS One. 2020;15: e0231870. doi: 10.1371/journal.pone.0231870.

Pamphlett R, Mak R, Lee J, Buckland ME, Harding AJ, Kum Jew S, et al. Concentrations of toxic metals and essential trace elements vary among individual neurons in the human locus ceruleus. PLoS One. 2020;15: e0233300. doi: 10.1371/journal.pone.0233300.

Pamphlett R, Satgunaseelan L, Kum Jew S, Doble PA, Bishop DP. Elemental bioimaging shows mercury and other toxic metals in normal breast tissue and in breast cancers. PLoS One. 2020;15: e0228226. doi: 10.1371/journal.pone.0228226.

Pamphlett R, Wang MX, Chan RC. Challenges in diagnosing hydroxychloroquine myopathy during the COVID-19 pandemic. Intern Med J. 2020;50: 1559-1562. doi: 10.1111/imj.15092.

Pearce A, Sy J, Lee M, Harding A, Mobbs R, Batchelor J, Suter C, Buckland M. Chronic traumatic encephalopathy in a former Australian rules football player diagnosed with Alzheimer's disease. Acta Neuropathologica Communications, 2020;8(1).

Satgunaseelan L, Allanson B, Asher R, Reddy R, Low H, Veness M, Gopal Iyer N, Smee R, Palme C, Gupta R, Clark J. The incidence of squamous cell carcinoma of the oral tongue is rising in young non-smoking women: An international multi-institutional analysis. Oral Oncology, 2020;110:104875.

Stringer RN, Jurkovicova-Tarabova B, Huang S, Haji-Ghassemi O, Idoux R, Liashenko A, Souza I, Rzhepetskyy Y, Lacinova L, Van Petegem F, Zamponi G, Pamphlett R, Weiss N. A rare CACNA1H variant associated with amyotrophic lateral sclerosis causes complete loss of Cav3.2 T-type channel activity. Molecular Brain, 2020;13(1).

Vasan K, Anand S, Satgunaseelan L, et al. Mismatch repair protein loss in cutaneous head and neck squamous cell carcinoma. Journal of Surgical Oncology, 2020;122(8):1755-1760.

2019

Azimi, A., Ali, M., Kaufman, K., Mann, G. and Fernandez‐Penas, P. (2018). Tape Stripped Stratum Corneum Samples Prove to be Suitable for Comprehensive Proteomic Investigation of Actinic Keratosis. PROTEOMICS - Clinical Applications, 13(3), p.1800084.

Bandres‐Ciga, S., Noyce, A., Hemani, G., Nicolas, A., Calvo, A., Mora, G., Arosio, A., Barberis, M., Bartolomei, I., Battistini, S., Benigni, M., Borghero, G., Brunetti, M., Calvo, A., Cammarosano, S., Cannas, A., Canosa, A., Capasso, M., Caponnetto, C., Caredda, C., Carrera, P., Casale, F., Cavallaro, S., Chiò, A., Colletti, T., Conforti, F., Conte, A., Corrado, L., Costantino, E., D'Alfonso, S., Fasano, A., Femiano, C., Ferrarese, C., Fini, N., Floris, G., Fuda, G., Giannini, F., Grassano, M., Ilardi, A., La Bella, V., Lattante, S., Logroscino, G., Logullo, F., Loi, D., Lunetta, C., Mancardi, G., Mandich, P., Mandrioli, J., Manera, U., Marangi, G., Marinou, K., Marrali, G., Marrosu, M., Mazzini, L., Melis, M., Messina, S., Moglia, C., Monsurro, M., Mora, G., Mosca, L., Occhineri, P., Origone, P., Pani, C., Penco, S., Petrucci, A., Piccirillo, G., Pirisi, A., Pisano, F., Pugliatti, M., Restagno, G., Ricci, C., Rita Murru, M., Riva, N., Sabatelli, M., Salvi, F., Santarelli, M., Sideri, R., Simone, I., Spataro, R., Tanel, R., Tedeschi, G., Tranquilli, S., Tremolizzo, L., Trojsi, F., Volanti, P., Zollino, M., Abramzon, Y., Arepalli, S., Baloh, R., Bowser, R., Brady, C., Brice, A., Broach, J., Campbell, R., Camu, W., Chia, R., Chiò, A., Cooper‐Knock, J., Cusi, D., Ding, J., Drepper, C., Drory, V., Dunckley, T., Eicher, J., Faghri, F., Feldman, E., Kay Floeter, M., Fratta, P., Geiger, J., Gerhard, G., Gibbs, J., Gibson, S., Glass, J., Hardy, J., Harms, M., Heiman‐Patterson, T., Hernandez, D., Jansson, L., Kamel, F., Kirby, J., Kowall, N., Laaksovirta, H., Landi, F., Le Ber, I., Lumbroso, S., MacGowan, D., Maragakis, N., Mouzat, K., Murphy, N., Myllykangas, L., Nalls, M., Nicolas, A., Orrell, R., Ostrow, L., Pamphlett, R., Pickering‐Brown, S., Pioro, E., Pliner, H., Pulst, S., Ravits, J., Renton, A., Rivera, A., Robbrecht, W., Rogaeva, E., Rollinson, S., Rothstein, J., Salvi, E., Scholz, S., Sendtner, M., Shaw, P., Sidle, K., Simmons, Z., Singleton, A., Stone, D., Sulkava, R., Tienari, P., Traynor, B., Trojanowski, J., Troncoso, J., Van Damme, P., Van Deerlin, V., Van Den Bosch, L., Zinman, L., Tienari, P., Stone, D., Nalls, M., Singleton, A., Chiò, A. and Traynor, B. (2019). Shared polygenic risk and causal inferences in amyotrophic lateral sclerosis. Annals of Neurology, 85(4), pp.470-481.

Buckland, M., Sy, J., Szentmariay, I., Kullen, A., Lee, M., Harding, A., Halliday, G. and Suter, C. (2019). Chronic traumatic encephalopathy in two former Australian National Rugby League players. Acta Neuropathologica Communications, 7(1).

Buckland, M., Sy, J., Szentmariay, I., Kullen, A., Lee, M., Harding, A., Halliday, G. and Suter, C. (2019). Correction to: Chronic traumatic encephalopathy in two former Australian National Rugby League players. Acta Neuropathologica Communications, 7(1).

Ebrahimkhani, S., Beadnall, H., Wang, C., Suter, C., Barnett, M., Buckland, M. and Vafaee, F. (2019). Serum Exosome MicroRNAs Predict Multiple Sclerosis Disease Activity after Fingolimod Treatment. Molecular Neurobiology.

Gedye, C., Sachchithananthan, M., Leonard, R., Jeffree, R., Buckland, M., Ziegler, D., Graeber, M., Day, B., McDonald, K., Lasocki, A., Nowak, A. (2019). Driving innovation through collaboration: development of clinical annotation datasets for brain cancer biobanking. Neuro-oncology practice, 7(1), 31-37.

Gross, C., Meyer, C., Bhatia, U., Yshii, L., Kleffner, I., Bauer, J., Tröscher, A., Schulte-Mecklenbeck, A., Herich, S., Schneider-Hohendorf, T., Plate, H., Kuhlmann, T., Schwaninger, M., Brück, W., Pawlitzki, M., Laplaud, D., Loussouarn, D., Parratt, J., Barnett, M., Buckland, M., Hardy, T., Reddel, S., Ringelstein, M., Dörr, J., Wildemann, B., Kraemer, M., Lassmann, H., Höftberger, R., Beltrán, E., Dornmair, K., Schwab, N., Klotz, L., Meuth, S., Martin-Blondel, G., Wiendl, H. and Liblau, R. (2019). CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome. Nature Communications, 10(1).

Hallal, S., Ebrahimkhani, S., Shivalingam, B., Graeber, M., Kaufman, K. and Buckland, M. (2019). The emerging clinical potential of circulating extracellular vesicles for non-invasive glioma diagnosis and disease monitoring. Brain Tumor Pathology, 36(2), pp.29-39.

Hallal, S., Mallawaaratchy, D., Wei, H., Ebrahimkhani, S., Stringer, B., Day, B., Boyd, A., Guillemin, G., Buckland, M. and Kaufman, K. (2018). Extracellular Vesicles Released by Glioblastoma Cells Stimulate Normal Astrocytes to Acquire a Tumor-Supportive Phenotype Via p53 and MYC Signaling Pathways. Molecular Neurobiology, 56(6), pp.4566-4581.

Hallal, S., Russell, B., Wei, H., Lee, M., Toon, C., Sy, J., Shivalingam, B., Buckland, M. and Kaufman, K. (2019). Extracellular Vesicles from Neurosurgical Aspirates Identifies Chaperonin Containing TCP1 Subunit 6A as a Potential Glioblastoma Biomarker with Prognostic Significance. PROTEOMICS, 19(1-2), p.1800157.

Lubomski, M., Sy, J., Buckland, M., Lee, A., Richards, B., Thompson, E., Fulham, M., Breen, N., Morris, K. and Halmagyi, G. (2018). Rheumatoid leptomeningitis presenting with an acute neuropsychiatric disorder. Practical Neurology, 19(1), pp.68-71.

Pamphlett, R. and Kum Jew, S. (2019). Mercury Is Taken Up Selectively by Cells Involved in Joint, Bone, and Connective Tissue Disorders. Frontiers in Medicine, 6.

Pamphlett, R., Kum Jew, S. and Cherepanoff, S. (2019). Mercury in the retina and optic nerve following prenatal exposure to mercury vapor. PLOS ONE, 14(8), p.e0220859.

Pamphlett, R., Kum Jew, S., Doble, P. and Bishop, D. (2019). Elemental Analysis of Aging Human Pituitary Glands Implicates Mercury as a Contributor to the Somatopause. Frontiers in Endocrinology, 10.

Sutherland, J., Steain, M., Buckland, M., Rodriguez, M., Cunningham, A., Slobedman, B. and Abendroth, A. (2019). Persistence of a T Cell Infiltrate in Human Ganglia Years After Herpes Zoster and During Post-herpetic Neuralgia. Frontiers in Microbiology, 10.

Triplett, J., Pamphlett, R., Wang, M. and Yiannikas, C. (2019). Anti‐SRP associated necrotizing autoimmune myopathy presenting with asymptomatically elevated creatine kinase. Muscle & Nerve, 59(3).

Neuropathology Research

Our Research Team

Selected Grants

Our Publications

2023

Neuropathology Research

Neuropathology Research

Our Organisation

Make a Donation

Our Hospitals

Right to Information

Plans

Publications

Quick Links