A NSW Government website
The RPA Intensive Care Service (ICS) conducts and participates in research activities at a local, national, and international level. Our participation in clinical research exerts a positive influence on the quality of care for all the critically ill adults that we care for. The ICS has an active local research program and makes a prolific contribution to investigator-initiated randomised clinical trials in intensive care medicine via its membership of the Australian and New Zealand Intensive Care Society Clinical Trials Group (ANZICS CTG).
RPA is one of the few hospitals in Australia which provides an Extracorporeal Membrane Oxygenation (ECMO) service. The Intensive Care Service, in collaboration with the Cardiology, Anaesthetics and Cardiothoracic Surgery Departments, has established an ECMO research program to further refine this advanced form of life support.
| Associate Professor David Gattas | Director of Research, Principal Investigator, Co-investigator |
| Heidi Buhr | Research Clinical Nurse Consultant, Principal Investigator, Co-investigator, Vice Chair of IRCIG |
| Cindy Liang | Research Coordinator, Co-investigator |
| Amount awarded | Grant and project details |
|---|---|
| $1,800,000 | NHMRC, 2019-2023 A phase III multicentre blinded randomised controlled clinical non-inferiority trial of cryopreserved platelets vs. conventional liquid-stored platelets for the management of post-surgical bleeding. Investigators: Reade M, Marks D, French C, McQuilten Z, Weinberg L, Irving D, Wood E, Bannon P, Johnson L, Gattas D |
| $44,000 | Intensive Care Foundation, 2023-2025 BLUSH trial - Phase 2b, randomised controlled trial of Bivalirudin versus Heparin in ECMO - a feasibility trail. Investigator: Southwood T |
| Abu Sardaneh A, Penm J, Oliver M, Gattas D, Mclachlan A, Patanwala A. Comparison of metaraminol versus no metaraminol on time to resolution of shock in critically ill patients. Eur J Hosp Pharm. 2023 Jul;30(4):214-220. doi: 10.1136/ejhpharm-2021-003035. Epub 2021 Oct 7. |
| Abu Sardaneh A, Penm J, Oliver M, Gattas D, McLachlan AJ, James C, Cella C, Aljuhani O, Acquisto NM, Patanwala AE. International pharmacy survey of peripheral vasopressor infusions in critical care (INFUSE). J Crit Care. 2023 Dec;78:154376. doi: 10.1016/j.jcrc.2023.154376. Epub 2023 Aug 2. |
| Bagshaw SM, Neto AS, Smith O, Weir M, Qiu H, Du B, Wang AY, Gallagher M, Bellomo R, Wald R; STARRT-AKI Investigators. Correction: Impact of renal- replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial. Intensive Care Med. 2023 Mar;49(3):381-383. doi: 10.1007/s00134-023-06976-2. Erratum for: Intensive Care Med. 2022 Dec;48(12):1736-1750. |
| Billot L, Bellomo R, Gallagher M, Gattas D, Hammond NE, Mackle D, Micallef S, Myburgh J, Navarra L, Saxena M, Taylor C, Young PJ, Finfer S; PLUS Study investigators and the ANZICS Clinical Trials Group. The Plasma-Lyte 148 versus Saline (PLUS) statistical analysis plan: a multicentre, randomised controlled trial of the effect of intensive care fluid therapy on mortality. Crit Care Resusc. 2023 Oct 18;23(1):24-31. doi: 10.51893/2021.1.OA2. |
| Burns KEA, Cook DJ, Xu K, Dodek P, Villar J, Jones A, Kapadia FN, Gattas DJ, Epstein SK, Pelosi P, Kefala K, Meade MO, Rizvi L; Canadian Critical Care Trials Group. Differences in directives to limit treatment and discontinue mechanical ventilation between elderly and very elderly patients: a substudy of a multinational observational study. Intensive Care Med. 2023 Oct;49(10):1181-1190. doi: 10.1007/s00134-023-07188-4. Epub 2023 Sep 22. |
| Burrell A, Ng S, Ottosen K, Bailey M, Buscher H, Fraser J, Udy A, Gattas D, Totaro R, Bellomo R, Forrest P, Martin E, Reid L, Ziegenfuss M, Eastwood G, Higgins A, Hodgson C, Litton E, Nair P, Orford N, Pellegrino V, Shekar K, Trapani T, Pilcher D. Blend to Limit OxygEN in ECMO: A RanDomised ControllEd Registry (BLENDER) Trial: Study Protocol and Statistical Analysis Plan. Crit Care Resusc. 2023 Aug 4;25(3):118-125. doi: 10.1016/j.ccrj.2023.06.001. Erratum in: Crit Care Resusc. 2024 Feb 01;26(1):60. |
| Dennis M, Southwood TJ, Oliver M, Nichol A, Burrell A, Hodgson C. Extracorporeal membrane oxygenation and Extracorporeal Membrane Oxygenation Cardiopulmonary Resusciation (ECPR) research priorities in Australia: A clinician survey. Aust Crit Care. 2023 Sep;36(5):828-831. doi: 10.1016/j.aucc.2022.11.009. Epub 2023 Jan 4. |
| Diehl A, Read AC, Southwood T, Buscher H, Dennis M, Nanjayya VB, Burrell AJC. The effect of restrictive versus liberal selection criteria on survival in ECPR: a retrospective analysis of a multi-regional dataset. Scand J Trauma Resusc Emerg Med. 2023 Dec 4;31(1):89. doi: 10.1186/s13049-023-01154-1. |
| Duffin SC, Askew JH, Southwood TJ, Forrest P, Plunkett B, Totaro RJ. An intensivist-led ECMO accreditation pathway and safety data over the first 4 years. Crit Care Resusc. 2023 Dec 14;26(1):41-46. doi: 10.1016/j.ccrj.2023.11.006. |
| Klein TT, O'Leary MJ, Staub L, Cavazzoni E. Organ donation by children in Australia, 2000-2019: impact of the 2009 National Reform Program. A population-based registry data study. Med J Aust. 2023 Jun 19;218(11):520-525. doi: 10.5694/mja2.51978. Epub 2023 May 29. |
| LOVIT-COVID Investigators, on behalf of the Canadian Critical Care Trials Group, and the REMAP-CAP Investigators; Adhikari NKJ, Hashmi M, Tirupakuzhi Vijayaraghavan BK, Haniffa R, Beane A, Webb SA, Angus DC, Gordon AC, Cook DJ, Guyatt GH, Berry LR, Lorenzi E, Mouncey PR, Au C, Pinto R, Ménard J, Sprague S, Masse MH, Huang DT, Heyland DK, Nichol AD, McArthur CJ, de Man A, Al-Beidh F, Annane D, Anstey M, Arabi YM, Battista MC, Berry S, Bhimani Z, Bonten MJM, Bradbury CA, Brant EB, Brunkhorst FM, Burrell A, Buxton M, Cecconi M, Cheng AC, Cohen D, Cove ME, Day AG, Derde LPG, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Goossens H, Green C, Higgins AM, Hills TE, Ichihara N, Jayakumar D, Kanji S, Khoso MN, Lawler PR, Lewis RJ, Litton E, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McQuilten ZK, McVerry BJ, Murthy S, Parke RL, Parker JC, Reyes LF, Rowan KM, Saito H, Salahuddin N, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Tolppa T, Trapani T, Turgeon AF, Turner AM, Udy AA, van de Veerdonk FL, Zarychanski R, Lamontagne F. Intravenous Vitamin C for Patients Hospitalized With COVID-19: Two Harmonized Randomized Clinical Trials. JAMA. 2023 Nov 14;330(18):1745-1759. doi: 10.1001/jama.2023.21407. Erratum in: JAMA. 2023 Dec 26;330(24):2398. Erratum in: JAMA. 2024 May 21;331(19):1680. |
| Patanwala AE, Moran B, Johnstone C, Koelzow H, Penm J. Effectiveness of Sublingual Buprenorphine for Pain Control in the ICU. Crit Care Med. 2023 Dec 1;51(12):1650-1658. doi: 10.1097/CCM.0000000000006031. Epub 2023 Aug 29. |
| Pilowsky JK, Elliott R, Roche MA. Association Between Preexisting Mental Health Disorders and Adverse Outcomes in Adult Intensive Care Patients: A Data Linkage Study. Crit Care Med. 2023 Apr 1;51(4):513-524. doi: 10.1097/CCM.0000000000005792. Epub 2023 Feb 8. |
| Pound G, Eastwood GM, Jones D, Hodgson CL; ANZ-CODE Investigators. ANZ-CODE management committee; Sites and Site Investigators. Potential role for extracorporeal membrane oxygenation cardiopulmonary resuscitation (E-CPR) during in-hospital cardiac arrest in Australia: A nested cohort study. Crit Care Resusc. 2023 Jun 24;25(2):90-96. doi: 10.1016/j.ccrj.2023.05.006. |
| Raasveld SJ, de Bruin S, Reuland MC, van den Oord C, Schenk J, Aubron C, Bakker J, Cecconi M, Feldheiser A, Meier J, Müller MCA, Scheeren TWL, McQuilten Z, Flint A, Hamid T, Piagnerelli M, Tomic Mahecic T, Benes J, Russell L, Aguirre-Bermeo H, Triantafyllopoulou K, Chantziara V, Gurjar M, Myatra SN, Pota V, Elhadi M, Gawda R, Mourisco M, Lance M, Neskovic V, Podbregar M, Llau JV, Quintana-Diaz M, Cronhjort M, Pfortmueller CA, Yapici N, Nielsen ND, Shah A, de Grooth HJ, Vlaar APJ; InPUT Study Group. Red Blood Cell Transfusion in the Intensive Care Unit. JAMA. 2023 Nov 21;330(19):1852-1861. doi: 10.1001/jama.2023.20737. |
| Reece L, Moran B, Ferrie S, Ansari N, Koh C, Allman-Farinelli M, Carey S. A global analysis of nutrition support practices in patients undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal malignancy. Clin Nutr ESPEN. 2023 Oct;57:297-304. doi: 10.1016/j.clnesp.2023.07.012. Epub 2023 Jul 11. |
| REMAP-CAP Investigators; Hills TE, Lorenzi E, Berry LR, Shyamsundar M, Al-Beidh F, Annane D, Arabi Y, Aryal D, Au C, Beane A, Bhimani Z, Bonten M, Bradbury CA, Brunkhorst FM, Burrell A, Buxton M, Calfee CS, Cecconi M, Cheng AC, Cove ME, Detry MA, Estcourt LJ, Fitzgerald M, Goligher EC, Goossens H, Green C, Haniffa R, Harrison DA, Hashmi M, Higgins AM, Huang DT, Ichihara N, Jayakumar D, Kruger PS, Lamontagne F, Lampro L, Lawler PR, Marshall JC, Mason AJ, McGlothlin A, McGuinness S, McQuilten ZK, McVerry BJ, Mouncey PR, Murthy S, Neal MD, Nichol AD, O'Kane CM, Parke RL, Parker JC, Rabindrarajan E, Reyes LF, Rowan KM, Saito H, Santos M, Saunders CT, Seymour CW, Shankar-Hari M, Sinha P, Thompson BT, Turgeon AF, Turner AM, van de Veerdonk F, Weis S, Young IS, Zarychanski R, Lewis RJ, McArthur CJ, Angus DC, Berry SM, Derde LPG, Webb SA, Gordon AC, McAuley DF. Simvastatin in Critically Ill Patients with Covid-19. N Engl J Med. 2023 Dec 21;389(25):2341-2354. doi: 10.1056/NEJMoa2309995. Epub 2023 Oct 25. |
| Ridley EJ, Chapple LS, Ainscough K, Burrell A, Campbell L, Dux C, Ferrie S, Fetterplace K, Jamei M, King V, Neto AS, Nichol A, Osland E, Paul E, Summers M, Marshall AP, Udy A. Nutrition care processes across hospitalisation in critically ill patients with COVID-19 in Australia: A multicentre prospective observational study. Aust Crit Care. 2023 Nov;36(6):955-960. doi: 10.1016/j.aucc.2023.01.003. Epub 2023 Jan 17. |
| Skrifvars MB, Luethi N, Bailey M, French C, Nichol A, Trapani T, McArthur C, Arabi YM, Bendel S, Cooper DJ, Bellomo R; EPO-TBI Investigators, the ANZICS Clinical Trials Group. The effect of recombinant erythropoietin on long-term outcome after moderate-to-severe traumatic brain injury. Intensive Care Med. 2023 Jul;49(7):831-839. doi: 10.1007/s00134-023-07141-5. Epub 2023 Jul 5. |
| Summers MJ, Chapple LS, Bellomo R, Chapman MJ, Ferrie S, Finnis ME, French C, Hurford S, Kakho N, Karahalios A, Maiden MJ, O'Connor SN, Peake SL, Presneill JJ, Ridley EJ, Tran-Duy A, Williams PJ, Young PJ, Zaloumis S, Deane AM; TARGET Protein Investigators and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Study protocol for TARGET protein: The effect of augmented administration of enteral protein to critically ill adults on clinical outcomes: A cluster randomised, cross-sectional, double cross-over, clinical trial. Crit Care Resusc. 2023 Sep 29;25(3):147-154. doi: 10.1016/j.ccrj.2023.08.001. |
| Wald R, Gaudry S, da Costa BR, Adhikari NKJ, Bellomo R, Du B, Gallagher MP, Hoste EA, Lamontagne F, Joannidis M, Liu KD, McAuley DF, McGuinness SP, Nichol AD, Ostermann M, Palevsky PM, Qiu H, Pettilä V, Schneider AG, Smith OM, Vaara ST, Weir M, Dreyfuss D, Bagshaw SM; STARRT-AKI Investigators. Initiation of continuous renal replacement therapy versus intermittent hemodialysis in critically ill patients with severe acute kidney injury: a secondary analysis of STARRT-AKI trial. Intensive Care Med. 2023 Nov;49(11):1305-1316. doi: 10.1007/s00134-023-07211-8. Epub 2023 Oct 10. |
| Worku E, Adam Worku D. Atraumatic Splenic Rupture in Legionella pneumophila Pneumonia. Case Rep Infect Dis. 2023 Jun 7;2023:9625170. doi: 10.1155/2023/9625170. |
| Worku E, Brodie D, Ling RR, Ramanathan K, Combes A, Shekar K. Venovenous extracorporeal CO2 removal to support ultraprotective ventilation in moderate-severe acute respiratory distress syndrome: A systematic review and meta-analysis of the literature. Perfusion. 2023 Jul;38(5):1062-1079. doi: 10.1177/02676591221096225. Epub 2022 Jun 2. |
| Worku E, Schmidt M, Shekar K. Is It Time to Put Low-Flow Extracorporeal Carbon Dioxide Removal to REST? Crit Care Med. 2023 Jul 1;51(7):973-976. Doi: 10.1097/CCM.0000000000005889. Epub 2023 Jun 15. |
| Worku ET, Win AM, Parmar D, Anstey C, Shekar K. Haematological Trends and Transfusion during Adult Extracorporeal Membrane Oxygenation: A Single Centre Study. J Clin Med. 2023 Mar 31;12(7):2629. doi: 10.3390/jcm12072629. |
| Writing Committee for the REMAP-CAP Investigators; Higgins AM, Berry LR, Lorenzi E, Murthy S, McQuilten Z, Mouncey PR, Al-Beidh F, Annane D, Arabi YM, Beane A, van Bentum-Puijk W, Bhimani Z, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Charles WN, Cove M, Detry MA, Estcourt LJ, Fagbodun EO, Fitzgerald M, Girard TD, Goligher EC, Goossens H, Haniffa R, Hills T, Horvat CM, Huang DT, Ichihara N, Lamontagne F, Marshall JC, McAuley DF, McGlothlin A, McGuinness SP, McVerry BJ, Neal MD, Nichol AD, Parke RL, Parker JC, Parry-Billings K, Peters SEC, Reyes LF, Rowan KM, Saito H, Santos MS, Saunders CT, Serpa-Neto A, Seymour CW, Shankar-Hari M, Stronach LM, Turgeon AF, Turner AM, van de Veerdonk FL, Zarychanski R, Green C, Lewis RJ, Angus DC, McArthur CJ, Berry S, Derde LPG, Gordon AC, Webb SA, Lawler PR. Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. JAMA. 2023 Jan 3;329(1):39-51. doi: 10.1001/jama.2022.23257. |
| Writing Committee for the REMAP-CAP Investigators; Lawler PR, Derde LPG, van de Veerdonk FL, McVerry BJ, Huang DT, Berry LR, Lorenzi E, van Kimmenade R, Gommans F, Vaduganathan M, Leaf DE, Baron RM, Kim EY, Frankfurter C, Epelman S, Kwan Y, Grieve R, O'Neill S, Sadique Z, Puskarich M, Marshall JC, Higgins AM, Mouncey PR, Rowan KM, Al-Beidh F, Annane D, Arabi YM, Au C, Beane A, van Bentum-Puijk W, Bonten MJM, Bradbury CA, Brunkhorst FM, Burrell A, Buzgau A, Buxton M, Cecconi M, Cheng AC, Cove M, Detry MA, Estcourt LJ, Ezekowitz J, Fitzgerald M, Gattas D, Godoy LC, Goossens H, Haniffa R, Harrison DA, Hills T, Horvat CM, Ichihara N, Lamontagne F, Linstrum KM, McAuley DF, McGlothlin A, McGuinness SP, McQuilten Z, Murthy S, Nichol AD, Owen DRJ, Parke RL, Parker JC, Pollock KM, Reyes LF, Saito H, Santos MS, Saunders CT, Seymour CW, Shankar-Hari M, Singh V, Turgeon AF, Turner AM, Zarychanski R, Green C, Lewis RJ, Angus DC, Berry S, Gordon AC, McArthur CJ, Webb SA. Effect of Angiotensin-Converting Enzyme Inhibitor and Angiotensin Receptor Blocker Initiation on Organ Support-Free Days in Patients Hospitalized With COVID-19: A Randomized Clinical Trial. JAMA. 2023 Apr 11;329(14):1183-1196. doi: 10.1001/jama.2023.4480. Erratum in: JAMA. 2023 Dec 26;330(24):2398. |
| Angriman F, Ferreyro BL, Angeloni N, da Costa BR, Wald R, Bagshaw SM, Adhikari NKJ; STARRT-AKI Investigators. The Effect of an Accelerated Renal Replacement Therapy Initiation Is Not Modified by Baseline Risk. Ann Am Thorac Soc. 2022 Sep;19(9):1613-1618. doi: 10.1513/AnnalsATS.202201-046RL. |
| Bagshaw SM, Neto AS, Smith O, Weir M, Qiu H, Du B, Wang AY, Gallagher M, Bellomo R, Wald R; STARRT-AKI Investigators. Impact of renal-replacement therapy strategies on outcomes for patients with chronic kidney disease: a secondary analysis of the STARRT-AKI trial. Intensive Care Med. 2022 Dec;48(12):1736-1750. doi: 10.1007/s00134-022-06912-w. Epub 2022 Nov 4. Erratum in: Intensive Care Med. 2023 Feb 9. |
| Barakat-Johnson M, Lai M, Stephenson J, Buhr H, Campbell J, Dolton A, Jones S, Leong T, Reddy N, Coyer F. Efficacy of a heel offloading boot in reducing heel pressure injuries in patients in Australian intensive care units: A single-blinded randomised controlled trial. Intensive & Critical Care Nursing, 2022, Vol 70. Available at: doi:https://doi-org.ezproxy.library.sydney.edu.au/10.1016/j.iccn.2022.103205 |
| Clayton NA, Ward EC, Nicholls C, Giannone R, Skylas K, Maitz PK. The addition of respiratory muscle strength training to facilitate swallow and pulmonary rehabilitation following massive tissue loss and severe deconditioning: A case series. Aust Crit Care. 2022 Mar;35(2):210-216. doi: 10.1016/j.aucc.2021.03.003. Epub 2021 Apr 23. |
| Dennis M; RESET Study Group and Sydney ECMO Research Interest Group (includes Duffin S, Forrest P, Oliver M, Totaro R, Southwood T, Gattas D et al). Out-of-hospital cardiac arrest outcomes, end-tidal carbon dioxide and extracorporeal cardiopulmonary resuscitation eligibility: New South Wales pilot data. Emerg Med Australas. 2022 Jun;34(3):452-455. doi: 10.1111/1742-6723.13972. Epub 2022 Apr 7. |
| Ferrie S, Weiss NB, Chau HY, Torkel S, Stepniewski ME. Association of Subjective Global Assessment with outcomes in the intensive care unit: a retrospective cohort study. Nutrition & Dietetics 2022; 2022;79:572-581. |
| Ferrie S. Evidence as foundation of practice. Editorial, Nutrition & Dietetics 2022; 79:184-186. |
| Finfer S, Micallef S, Hammond N, Navarra L, Bellomo R, Billot L, Delaney A, Gallagher M, Gattas D, Li Q, Mackle D, Mysore J, Saxena M, Taylor C, Young P, Myburgh J; PLUS Study Investigators & ANZICS Clinical Trials Group. Balanced Multielectrolyte Solution versus Saline in Critically Ill Adults. N Engl J Med. 2022 Mar 3;386(9):815-826. doi: 10.1056/NEJMoa2114464. Epub 2022 Jan 18. |
| Hodgson C, Bailey M, Bellomo R, Brickell K, Broadley T, Buhr H, Gabbe B, Gould D, Harrold M, Higgins A, Hurford S, Iwashyna T, Serpa Neto A, Nichol A, Presneill J, Schaller S, Sivasuthan, J, Tipping C, Webb S, Young P; TEAM Study Investigators & ANZICS Clinical Trials Group (2022). Early active mobilization during mechanical ventilation in the ICU. New England Journal of Medicine, 387(19), 1747-1758. doi:10.1056/nejmoa2209083 |
| Hodgson C, Higgins A, Bailey M, Anderson S, Bernard S, Fulcher B, Koe D, Linke N, Board J, Brodie D, Buhr H, Burrell A, Cooper D, Fan E, Fraser J, Gattas D, Hopper I, Huckson S, Litton E, McGuinness S, Nair P, Orford N, Parke R, Pellegrino V, Pilcher D, Sheldrake J, Reddi B, Stub D, Trapani T, Udy A, Serpa Neto, A; EXCEL Study Investigators on behalf of the International ECMO Network & ANZICS Clinical Trials Group (2022). Incidence of death or disability at 6 months after Extracorporeal Membrane Oxygenation in Australia: A prospective, multicentre, registry-embedded cohort study. The Lancet Respiratory Medicine, 10(11), 1038-1048. doi:10.1016/s2213-2600(22)00248-x |
| Hodgson CL, Higgins AM, Bailey MJ, Mather AM, Beach L, Bellomo R, Bissett B, Boden IJ, Bradley S, Burrell A, Cooper DJ, Fulcher BJ, Haines KJ, Hodgson IT, Hopkins J, Jones AYM, Lane S, Lawrence D, van der Lee L, Liacos J, Linke NJ, Gomes LM, Nickels M, Ntoumenopoulos G, Myles PS, Patman S, Paton M, Pound G, Rai S, Rix A, Rollinson TC, Tipping CJ, Thomas P, Trapani T, Udy AA, Whitehead C, Anderson S, Neto AS; COVID-Recovery Study Investigators and the ANZICS Clinical Trials Group. Comparison of 6-Month Outcomes of Survivors of COVID-19 versus Non-COVID-19 Critical Illness. Am J Respir Crit Care Med. 2022 May 15;205(10):1159-1168. doi: 10.1164/rccm.202110-2335OC. Erratum in: Am J Respir Crit Care Med. 2022 Sep 1;206(5):653. |
| Karcher C, Jurisevic C, Southwood T, McCormack D, Rogers A, Levine A, Dunning J. The Australasian ANZSCTS/ANZICS Guidelines on Cardiothoracic Advanced Life Support (CALS-ANZ). Critical Care and Resuscitation 24, no. 3 (2022): 218-223. https://doi.org/10.51893/2022.3.AS3. |
| O'Leary MJ, Skowronski G, Critchley C, O'Reilly L, Forlini C, Sheahan L, Stewart C, Kerridge I. Death determination, organ donation and the importance of the Dead Donor Rule following withdrawal of life-sustaining treatment: a survey of community opinions. Intern Med J. 2022 Feb;52(2):238-248. doi: 10.1111/imj.15221. |
| Patanwala A, Moran B, Johnstone C, Koelzow H, Penm J (2022). Effectiveness of Transdermal Buprenorphine for Pain Control in the ICU After Major Surgical Procedures. Critical care explorations, 4(4). |
| Pound GM, Jones D, Eastwood GM, Paul E, Hodgson CL; Australia and New Zealand Cardiac Arrest Outcome and Determinants of ECMO (ANZ-CODE) Investigators. Long-Term Functional Outcome and Quality of Life Following In-Hospital Cardiac Arrest-A Longitudinal Cohort Study. Crit Care Med. 2022 Jan 1;50(1):61-71. doi: 10.1097/CCM.0000000000005118. |
| Premraj L, Brown A, Burrell A, Fraser J, Pilcher D. Hyperoxia during venoarterial ECMO: Culprit or co-variate? A comment from the BLENDER investigators. Crit Care 26, 345 (2022). https://doi.org/10.1186/s13054-022-04213-8 |
| Reade MC, Marks DC, Howe B, McGuinness S, Parke R, Navarra L, Charlewood R, Johnson L, McQuilten Z; CLIP-II and CLIPNZ-II Investigators.; CLIP-II and CLIPNZ-II Investigators (includes Gattas D). Cryopreserved platelets compared with liquid-stored platelets for the treatment of surgical bleeding: protocol for two multicentre randomised controlled blinded non-inferiority trials (the CLIP-II and CLIPNZ-II trials). BMJ Open. 2022 Dec 20;12(12):e068933. doi: 10.1136/bmjopen-2022-068933. |
| REMAP-CAP Writing Committee for the REMAP-CAP Investigators. Effect of Antiplatelet Therapy on Survival and Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2022;327(13):1247-1259. doi:10.1001/jama.2022.2910 |
| Thiara S, Serpa Neto A, Burrell AJC, Fulcher BJ, Hodgson CL. Association of Respiratory Parameters at Venovenous Extracorporeal Membrane Oxygenation Liberation With Duration of Mechanical Ventilation and ICU Length of Stay: A Prospective Cohort Study. Crit Care Explor. 2022 May 2;4(5):e0689. doi: 10.1097/CCE.0000000000000689. |
| Thomson IK, Hedley J, Rosales BM, Wyburn K, O'Leary MJ, Webster AC. Potential organ donors with primary brain tumours: missed opportunities for donation and transplantation identified in Australian cohort study 2010-2015. ANZ J Surg. 2022 Nov;92(11):2996-3003. doi: 10.1111/ans.18037. Epub 2022 Sep 21. |
| Tran D, Gibson H, Maiorana A, Verrall C, Baker D, Clode M, Lubans D, Zannino D, Bullock A, Ferrie S, Briody J, Simm P, Wijesekera, D'Almeida M, Gosbell S, Davis G, Weintraub R, Keech A, Puranik R, Ugander M, Justo R, Zentner D, Majumdar A, Grigg L, Coombes J, d'Udekem Y, Morris N, Ayer J, Celermajer D, Cordina R. Exercise intolerance, benefits, and prescription for people living with a Fontan circulation: the Fontan Fitness Intervention Trial (F-FIT)-rationale and design. Frontiers in Pediatrics 2022; vol 9: article 799125. |
| Waller KMJ, De La Mata NL, Rosales BM, Hedley JA, Kelly PJ, Thomson IK, O'Leary MJ, Cavazzoni E, Ramachandran V, Rawlinson WD, Wyburn KR, Webster AC. Characteristics and Donation Outcomes of Potential Organ Donors Perceived to Be at Increased Risk for Blood-borne Virus Transmission: An Australian Cohort Study 2010-2018. Transplantation. 2022 Feb 1;106(2):348-357. doi: 10.1097/TP.0000000000003715. |
| Writing Committee for the REMAP-CAP Investigators. Long-term (180-Day) Outcomes in Critically Ill Patients With COVID-19 in the REMAP-CAP Randomized Clinical Trial. JAMA. 2023;329(1):39-51. doi:10.1001/jama.2022.23257 |
| Zampieri FG, da Costa BR, Vaara ST, Lamontagne F, Rochwerg B, Nichol AD, McGuinness S, McAuley DF, Ostermann M, Wald R, Bagshaw SM; STARRT-AKI Investigators. A Bayesian reanalysis of the Standard versus Accelerated Initiation of Renal-Replacement Therapy in Acute Kidney Injury (STARRT-AKI) trial. Crit Care. 2022 Aug 25;26(1):255. doi: 10.1186/s13054-022-04120-y. |
| Abu Sardaneh A, Penm J, Oliver M, Gattas D, Mclachlan A, Patanwala A. Comparison of metaraminol versus no metaraminol on time to resolution of shock in critically ill patients. Eur J Hosp Pharm. 2021 Oct 7:ejhpharm-2021-003035. doi: 10.1136/ejhpharm-2021-003035. Epub ahead of print. |
| Burns KEA, Rizvi L, Cook DJ, Lebovic G, Dodek P, Villar J, Slutsky AS, Jones A, Kapadia FN, Gattas DJ, Epstein SK, Pelosi P, Kefala K, Meade MO; Canadian Critical Care Trials Group. Ventilator Weaning and Discontinuation Practices for Critically Ill Patients. JAMA. 2021 Mar 23;325(12):1173-1184. doi: 10.1001/jama.2021.2384. |
| Carey S, Waller J, Wang LY, Ferrie S. Qualifying thirst distress in the perioperative setting - validation of a patient-reported outcome measure. Journal of Perioperative Nursing 2021; 34(4): e38-e44. |
| Cartwright B, Bruce HM, Kershaw G, Cai N, Othman J, Gattas D, Robson JL, Hayes S, Alicajic H, Hines A, Whyte A, Chaikittisilpa N, Southwood TJ, Forrest P, Totaro RJ, Bannon PG, Dunkley S, Chen VM, Dennis M. Hemostasis, coagulation and thrombin in venoarterial and venovenous extracorporeal membrane oxygenation: the HECTIC study. Sci Rep. 2021 Apr 12;11(1):7975. doi: 10.1038/s41598-021-87026-z. |
| Chapple LS, Summers MJ, Bellomo R, Chapman MJ, Davies AR, Ferrie S et al, Use of a protein-intense enteral nutrition formula to increase protein delivery to critically ill patients: A randomised, blinded, parallel-group, feasibility trial. JPEN 2021; 69(4):699-709. |
| Ferrie S, Webster A, Wu B, Tan C, Carey S. Gastrointestinal surgery and the gut microbiome: a systematic literature review. European Journal of Clinical Nutrition 2021;75(1):12-25. |
| Hodgson CL, Fulcher B, Mariajoseph FP, Burrell AJC, Pellegrino V, Brodie D, Fan E; SCOPE Study Investigators on behalf of the International ECMO Network. A Core Outcome Set for Research in Patients on Extracorporeal Membrane Oxygenation. Crit Care Med. 2021 Dec 1;49(12):e1252-e1254. doi: 10.1097/CCM.0000000000005110. |
| Maiden MJ, Bone A, Fitzpatrick M; George Institute for Global Health, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. Physical restraint of patients in Australia and New Zealand intensive care units. Intensive Care Med. 2021 Feb;47(2):234-236. doi: 10.1007/s00134-020-06287-w. Epub 2020 Nov 12. |
| McEwen K, Brodie L. Lung transplantation for silicosis and recovery: an Australian case study. British Journal of Nursing. 2021;30(3):178-183. doi:10.12968/bjon.2021.30.3.178. |
| Murthy TA, Bellomo R, Chapman MJ, Deane AM, Ferrie S, et al. Protein delivery in mechanically ventilated adults in Australia and New Zealand: current practice. Critical Care and Resuscitation 2021; 23(4):386-393. |
| Presneill J, Bellomo R, Brickell K, Buhr H, Gabbe B, Gould D, Harrold M, Higgins A, Hurford S, Iwashyna T, Neto A, Nichol A, Schaller S, Sivasuthan J, Tipping C, Webb S, Young P, Hodgson C. Protocol and statistical analysis plan for the phase 3 randomised controlled Treatment of Invasively Ventilated Adults with Early Activity and Mobilisation (TEAM III) trial. Critical Care and Resuscitation, 2021 [online] 23(3), pp.262-272. Available at: https://ccr.cicm.org.au/journal-editions/2021/september/toc-september-2…. |
| REMAP-CAP Investigators. Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19. N Engl J Med. 2021 Apr 22;384(16):1491-1502. doi: 10.1056/NEJMoa2100433. Epub 2021 Feb 25. |
| REMAP-CAP Investigators. Lopinavir-ritonavir and hydroxychloroquine for critically ill patients with COVID-19: REMAP-CAP randomized controlled trial. Intensive Care Med. 2021 Aug;47(8):867-886. doi: 10.1007/s00134-021-06448-5. Epub 2021 Jul 12. |
| Sardaneh AA, Penm J, Oliver M, Gattas D, McLachlan AJ, Patanwala AE. Pharmacoepidemiology of metaraminol in critically ill patients with shock in a tertiary care hospital. Aust Crit Care. 2021 Nov;34(6):573-579. doi: 10.1016/j.aucc.2021.01.002. Epub 2021 Mar 1. |
| The ATTACC, ACTIV-4a, and REMAP-CAP Investigators. Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19. N Engl J Med [online] 2021 Aug 4; 385(9), pp.790-802. |
| The REMAP-CAP Investigators. Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19. N Engl J Med [online] 2021 Feb 25; 384(16), pp.1491-1502. |
| The REMAP-CAP, ACTIV-4a, and ATTACC Investigators. Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19. N Engl J Med [online] 2021 Aug 26; 384(16), pp.1491-1502. |
| Wilson NM, Marks GB, Eckhardt A, Clarke AM, Young FP, Garden FL, Stewart W, Cook TM & Tovey ER 2021, 'The effect of respiratory activity, non?invasive respiratory support and facemasks on aerosol generation and its relevance to COVID?19', Anaesthesia, vol. 76, no. 11, pp. 1465-1474. |
| Writing Committee for the REMAP-CAP Investigators. Effect of Convalescent Plasma on Organ Support-Free Days in Critically Ill Patients With COVID-19: A Randomized Clinical Trial. JAMA. 2021 Nov 2;326(17):1690-1702. doi: 10.1001/jama.2021.18 |
| Angus DC, Derde L, Al-Beidh F, Annane D, Arabi Y, Beane A, Van Bentum-Puijk W, Berry L, Bhimani Z, Bonten M, Bradbury C, Brunkhorst F, Buxton M, Buzgau A, Cheng AC, De Jong M, Detry M, Estcourt L, Fitzgerald M, Goossens H, Green C. Effect of Hydrocortisone on Mortality and Organ Support in Patients With Severe COVID-19: The REMAP-CAP COVID-19 Corticosteroid Domain Randomized Clinical Trial. JAMA : the Journal of the American Medical Association. , 2020, Vol.324(13), p.1317-1329. |
| Chapple LS, Fetterplace K, Asrani V, Burrell A, Cheng A, Collins P, Doola R, Ferrie S, Marshall AP, Ridley EJ. Nutrition management for critically and acutely unwell hospitalised patients with coronavirus disease 2019 (COVID-19) in Australia and New Zealand. Nutrition & Dietetics 2020;77(4):426-436. |
| Chapple LS, Fetterplace K, Asrani V, Burrell A, Cheng A, Collins P, Doola R, Ferrie S, Marshall AP, Ridley EJ. Nutrition management for critically and acutely unwell hospitalised patients with COVID-19 in Australia and New Zealand. Australian Critical Care 2020; 33(5):399-406. |
| Chapple LS, Summers MJ, Bellomo R, Chapman MJ, Davies AR, Ferrie S et al. Use of a protein-intense enteral nutrition formula to increase protein delivery to critically ill patients: A randomised, blinded, parallel-group, feasibility trial. Journal of Parenteral and Enteral Nutrition 2020. |
| Deane AM, Little L, Bellomo R, Chapman MJ, Davies A, Ferrie S et al. Outcomes six-months after 100% or 70% of enteral energy calorie requirements during critical illness. American Journal of Respiratory and Critical Care Medicine 2020; 201(7):814-822. |
| Dennis M, Buscher H, Gattas D, Burns B, Habig K, Bannon P, Patel S, Buhr H, Reynolds C, Scott S, Nair P, Hayman J, Granger E, Lovett R, Forrest P, Coles J, Lowe D. Prospective observational study of mechanical cardiopulmonary resuscitation, extracorporeal membrane oxygenation and early reperfusion for refractory cardiac arrest in Sydney: the 2CHEER study. Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine, 2020, Vol.22(1), p.26-34. |
| Ferrie S. What is nutritional assessment? A practical guide for critical care clinicians. Australian Critical Care 2020; 33 (3): 295-299. |
| Heinonen T, Ferrie S, Ferguson C. Gut function in the intensive care unit - What is 'normal'? Australian Critical Care 2020; 33(2):151-154. |
| Hogan S, Solomon M, Rangan A, Ferrie S, Carey S. The impact of preoperative immunonutrition and standard polymeric supplements on patient outcomes after pelvic exenteration surgery, taking compliance into consideration - a randomised controlled trial. Journal of Parenteral and Enteral Nutrition 2020; 44(5):806-814. |
| Lehmann S, Ferrie S, Carey S. Nutrition management in patients with chronic gastrointestinal motility disorders: a systematic literature review. Nutrition in Clinical Practice 2020; 35(2): 219-230. |
| Linke NJ, Fulcher B, Engeler DM, Anderson S, Bailey M, Bernard S, Board JV, Brodie D, Buhr H, Burrell AJC, Cooper DJ, Fan E, Fraser JF, Gattas DJ, Higgins AM, Hopper IK, Huckson S, Litton E, McGuinness SP, Nair P, Orford N. A survey of extracorporeal membrane oxygenation practice in 23 Australian adult intensive care units. Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine, 2020, Vol.22(2), p.166-170. |
| Skowronski G, O'Leary MJ, Critchley C, O'Reilly L, Forlini C, Ghinea N, Sheahan L, Stewart C, Kerridge I. Death, dying and donation: Community perceptions of brain death and their relationship to decisions regarding withdrawal of vital organ support and organ donation. Internal Medicine Journal 2020;50:1192-1201. |
| Van Haren FMP, Carter A, Cavazzoni E, Chapman M, D'Costa RL, Jones SL, McGee A, Moodie S, Nunnink L, O'Leary M, Opdam H, Radford S, Turner AJ, Martin D. Conflicts of interest in the context of end of life care for potential organ donors in Australia. Journal of Critical Care 2020;59:166-171. |
| Waller KMJ, De La Mata NL, Hedley JA, Rosales BM, O'Leary MJ, Cavazzoni E, Ramachandra V, Rawlinson ED, Kelly PJ, Wyburn KR, Webster AC. New blood borne virus infections among organ transplant recipients: an Australian data-linked cohort study examining donor-transmissions and other HIV, hepatitis C and hepatitis B notifications, 2000-2015. Transplant Infectious Disease 2020;22:e13437. |
| Waller KMJ, Hedley JA, Rosales BM, De La Mata NL, Thomson IK, Walker J, Kelly PJ, O'Leary MJ, Cavazzoni E, Wyburn KR, Webster AC. Effect of language and country of birth on the consent process and medical suitability of potential organ donors; a linked-data cohort study 2010-2015. Journal of Critical Care 2020;57:23-29. |
| Warrillow S, Fisher C, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, García Álvarez M, Bellomo R. Coagulation abnormalities, bleeding, thrombosis, and management of patients with acute liver failure in Australia and New Zealand. Journal of gastroenterology and hepatology 2020, Vol.35(5), p.846-854. |
| Warrillow S, Fisher C, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, García Álvarez M, Bellomo R. Continuous renal replacement therapy and its impact on hyperammonaemia in acute liver failure. Critical Care and Resuscitation: Journal of the Australasian Academy of Critical Care Medicine 2020, Vol.22(2), p.158-165. |
| Young PJ, Bagshaw SM, Forbes AB, Nichol AD, Wright SE, Bailey M, Bellomo R, Beasley R, Brickell K, Eastwood GM, Gattas DJ, Van Haren F, Litton E, Mackle DM, McArthur CJ, McGuinness SP, Mouncey PR, Navarra L, Opgenorth D, Pilcher D. Effect of Stress Ulcer Prophylaxis with Proton Pump Inhibitors vs Histamine-2 Receptor Blockers on In-Hospital Mortality Among ICU Patients Receiving Invasive Mechanical Ventilation: The PEPTIC Randomized Clinical Trial. JAMA : the Journal of the American Medical Association, 2020, Vol.323(7), p.616-626. |
| Awwad, S., Tarvade, S., Piccardi, M., Gattas, D. (2019). The use of privacy-protected computer vision to measure the quality of healthcare worker hand hygiene. International Journal for Quality in Health Care, 31(1), 36-42. |
| Burns KEA, Rizvi L, Cook DJ, Dodek P, Slutsky AS, Jones A, Villar J, Kapadia FN, Gattas DJ, Epstein SK, Meade MO; Canadian Critical Care Trials Group. Variation in the practice of discontinuing mechanical ventilation in critically ill adults: study protocol for an international prospective observational study. BMJ Open. 2019 Sep 8;9(9)e031775. Doi:10.1136/bmjopen-2019-031775.. |
| Carey S, Lau K, Ferrie S.Feasibility of home jejunal feeding following discharge after major gastrointestinal surgery - a randomised controlled trial. Nutrition & Food Sciences 2019;10:98-109. |
| Cheng J, Witney-Cochrane K, Cunich M, Ferrie S, Carey S. Defining and quantifying preventable and non-preventable hospital-acquired malnutrition. Nutrition & Dietetics 2019; 76(5): 620-627. |
| Das A, Anstey M, Bass F, Blythe D, Buhr H, Campbell L, Davda A, Delaney A, Gattas D, Green C, Ferrier J, Hammond N, Palermo A, Pellicano S, Phillips M, Regli A, Roberts B, Ross-King M, Sarode V, Simpson S, Spiller S, Sullivan K, Tiruvoipati R, van Haren F, Waterson S, Yaw LK, Litton E. Internet health information use by surrogate decision makers of patients admitted to the intensive care unit: a multicentre survey. Crit Care Resusc. 2019 Dec;21(4):305-10. |
| Dennis M, Zmudzki F, Burns B, Scott S, Gattas D, Reynolds C, Buscher H, Forrest P; Sydney ECMO Research Interest Group. Cost effectiveness and quality of life analysis of extracorporeal cardiopulmonary resuscitation (ECPR) for refractory cardiac arrest. Resuscitation. 2019 Jun;139:49-56. doi:10.1016/j.resuscitation.2019.03.021. Epub 2019 Mar 26. |
| Ferrie S. Does infusion time affect the retention of parenteral trace elements? British Journal of Nutrition 2019; 122(1): 56-62. |
| Hammond NE, Bellomo R, Gallagher M, Gattas D, Glass P, Mackle D, Micallef S, Myburgh J, Saxena M, Taylor C, Young P, Finfer S. The Plasma-Lyte 148 versus Saline (PLUS) study protocol amendment. Crit Care Resusc. 2019 Dec;21(4):284-86. |
| Hedley JA, Chang N, Kelly PJ, Rosales BM, Wyburn K, O'Leary M, Cavazzoni E, Webster AC. Weekend effect: analysing temporal trends in solid organ donation. ANZ J Surg. 2019 Sep;89(9):1068-1074. doi: 10.1111/ans.15015. Epub 2019 Feb 1. |
| Reade MC, Marks DC, Bellomo R, Deans R, Faulke DJ, Fraser JF, Gattas DJ, Holley AD, Irving DO, Johnson L, Pearse BL, Royse AG, Wong J; Cryopreserved vs Liquid Platelet (CLIP) Investigators, the Australian and New Zealand College of Anaesthetists Clinical Trials Network, and the Australian and New Zealand Intensive Care Society Clinical Trials Group. A randomized, controlled pilot clinical trial of cryopreserved platelets for perioperative surgical bleeding: the CLIP-I trial (Editorial, p. 2759). Transfusion. 2019 Sep;59(9):2794-2804. doi: 10.1111/trf.15423. Epub 2019 Jul 10.. |
| Thomson IK, Rosales BM, Kelly PJ, Wyburn K, Waller KMJ, Hirsch D, O'Leary MJ, Webster AC. Epidemiology and Comorbidity Burden of Organ Donor Referrals in Australia: Cohort Study 2010-2015. Transplant Direct. 2019 Oct 17;5(11):e504. doi: 10.1097/TXD.0000000000000938. eCollection 2019 Nov. |
| Warrillow S, Tibballs H, Bailey M, McArthur C, Lawson-Smith P, Prasad B, Anstey M, Venkatesh B, Dashwood G, Walsham J, Holt A, Wiersema U, Gattas D, Zoeller M, Garcia Alvarez M, Bellomo R; Australasian Management of Acute Liver Failure Investigators (AMALFI). Characteristics, management and outcomes of patients with acute liver failure admitted to Australasian intensive care units. Crit Care Resusc. 2019 Sep;21(3):188-199. |