Ear Nose and Throat Surgery Research

The Department of Otolaryngology Head and Neck Surgery at Royal Prince Alfred Hospital is founded on the idea of academic and surgical excellence in otorhinolaryngologic surgery and management of these conditions. Our surgeons have a diverse range of interests and specialise in multiple areas including head and neck surgical oncology, rhinology, anterior and lateral skull base surgery and otology including cochlear implantation. Our department is committed to an evidence-based approach to patient education and appropriate care, the department strives to further the field through high quality research.

Selected Grants

Amount awarded	Grant and project details
$387,000	The Garnett Passe and Rodney Williams Memorial Foundation Project Grants/ Fellowships, 2025-2027 The Use Of Liquid Biopsy For High-Risk Stratification Of HPV16-Positive Oropharyngeal Cancer Patients. Investigators: Tran N, Elliott M, Tran NH, Sais D.
$10,000	Adept Medical, 2024-2025 An ergonomic analysis of an armrest in endoscopic sinus surgery. Investigator: Campbell R.
$88,600	Grace Kathleen Fanton Bequest Research Grant, 2022-2026 Bridging the Gap: A Comparative Study Between a Mouse Model of Endolymphatic Hydrops and Human Meniere’s Disease Investigators: Camp A, Mukherjee P, Creber N.

Our Publications

2024

Png LH, Kalish L, Campbell RG, Seresirikachorn K, Albrecht T, Raji N, Choy C, Rimmer J, Earls P, Sacks R, Harvey RJ. Predictors of persistent disease in biologic treated type 2 diffuse/eosinophilic chronic rhinosinusitis undergoing surgery. Int Forum Allergy Rhinol. 2024 May;14(5):909-918. doi: 10.1002/alr.23282. Epub 2023 Oct 8.

Subramaniam N, Heller G, Clark JR, Gupta R, Goldstein D, de Almeida JR, Hosni A, Balasubramanian D, Thankappan K, Iyer S, Batstone M, Iyer NG, Smee RI, Chandrasekhar NH, Pillai V, Shetty V, Rangappa V, Veness M, Low TH. Improving accuracy in nodal staging of oral cancer: Proposal of a new system. Surg Oncol. 2024 Feb;52:102033. doi: 10.1016/j.suronc.2024.102033. Epub 2024 Jan 5.

Venchiarutti RL, Clark JR AM, Palme CE, Dwyer P, Tahir ARM, Hill J, Ch'ng S, Elliott MS, Young JM. Associations between patient-level health literacy and diagnostic time intervals for head and neck cancer: A prospective cohort study. Head Neck. 2024 Apr;46(4):857-870. doi: 10.1002/hed.27633. Epub 2024 Jan 11.

Balgobind S, Cheung VKY, Luk P, Low TH, Wykes J, Wu R, Lee J, Ch'ng S, Palme CE, Clark JR, Gupta R. Prognostic and predictive biomarkers in head and neck cancer: something old, something new, something borrowed, something blue and a sixpence in your shoe. Pathology. 2024 Mar;56(2):170-185. doi: 10.1016/j.pathol.2023.11.005. Epub 2023 Dec 19. Erratum in: Pathology. 2024 Oct;56(6):930. doi: 10.1016/j.pathol.2024.07.001.

Noor A, Mair MD, Gupta R, Elliott MS, Wykes J, Palme CE, Clark JR, Low TH. When should patients with T1N0 oral squamous cell carcinoma be considered for elective neck dissection? ANZ J Surg. 2024 May;94(5):854-860. doi: 10.1111/ans.18884. Epub 2024 Jan 30.

Chong AXJ, Alvarado R, Rimmer J, Campbell RG, Kalish L, Png LH, Harvey RJ. Comparison of Allergen Immunotherapy Alone and in Conjunction With Turbinate Surgery for Nasal Obstruction in Perennial Allergic Rhinitis Patients. Ann Otol Rhinol Laryngol. 2024 Jun;133(6):545-553. doi: 10.1177/00034894241234593. Epub 2024 Feb 27.

Yung AE, Luong J, Crouch G, Hong AM, Ananda A, Taylor S, Kotronakis I, Low TH, Elliott MS, McBride K, Rutherford C, Clark JR, Ch'ng S. First Phase Development of a Patient-reported Outcome Measure for Midface Oncology. Plast Reconstr Surg Glob Open. 2024 Mar 22;12(3):e5689. doi: 10.1097/GOX.0000000000005689.

Deutsch F, Sais D, Keatinge N, Hill M, Tran NH, Elliott M, Tran N. Biplex quantitative PCR to detect transcriptionally active human papillomavirus 16 from patient saliva. BMC Cancer. 2024 Apr 10;24(1):442. doi: 10.1186/s12885-024-12125-9.

Chang N, Lennard K, Rao A, Elliott M, Dharan N, Wong J. Polymicrobial arcanobacterium haemolyticum intracerebral abscess: A case report and review of the literature. IDCases. 2024 Apr 15;36:e01960. doi: 10.1016/j.idcr.2024.e01960.

Sedaghat AR, Campbell RG, Douglas RG, Fokkens WJ, Hamizan AW, Korban ZR, Lee VS, Macias-Valle L, Romano FR, Snidvongs K, Alsaleh S. Outcome measures for chronic rhinosinusitis with nasal polyps. Rhinology. 2024 Aug 31;62(34):1-37. doi: 10.4193/Rhin24.090.

Campbell RG, Zadro JR, Gamble AR, Chan CL, Mackey MG, Osie G, Png LH, Douglas RG, Pappas E. Work-Related Musculoskeletal Disorders in Endoscopic Sinus and Skull Base Surgery: A Systematic Review With Meta-analysis. Otolaryngol Head Neck Surg. 2024 Dec;171(6):1650-1669. doi: 10.1002/ohn.892. Epub 2024 Jul 6.

Meerwein CM, Seresirikachorn K, Lindsay B, Sacks PL, Kalish L, Campbell RG, Sacks RR, Harvey RJ. Sphenoid Sinus Fungal Ball and Reestablishing Sinus Function. Laryngoscope. 2024 Dec;134(12):4888-4892. doi: 10.1002/lary.31635. Epub 2024 Jul 12.

Ahmadzada S, Seresirikachorn K, Png LH, Campbell RG, Kalish L, Harvey RJ. Prelacrimal-Transmaxillary Approach to Lateral Sphenoid Recess Skull Base Defects. Laryngoscope. 2024 Dec;134(12):4918-4922. doi: 10.1002/lary.31653. Epub 2024 Aug 1.

Ma J, Aung YM, Cheng K, Dunn M, Mukherjee P, Manzie T, Low TH, Wykes J, Leinkram D, Clark J. A comparison of preoperative soft tissue contour versus bone accuracy as a predictor of quality of life outcomes in osseous free flap jaw reconstruction using occlusal-based virtual surgical planning. J Plast Reconstr Aesthet Surg. 2024 Oct;97:50-58. doi: 10.1016/j.bjps.2024.07.061. Epub 2024 Jul 26.

Jeong YJ, Dunn M, Manzie T, Howes D, Wykes J, Palme CE, Leinkram D, Low TH, Oberoi R, Aung YM, Ormsby C, Clark J. Jaw in a day surgery: early experience with 19 patients at an Australian tertiary referral center. ANZ J Surg. 2024 Sep;94(9):1531-1538. doi: 10.1111/ans.19203. Epub 2024 Aug 19.

Pradhan P, Wan KZ, Chan L, Low TH, Wu R, Lee JH, Palme CE, Clark JR, Venchiarutti RL. A qualitative exploration of the pathway to diagnosis and treatment of cutaneous squamous cell carcinoma of the head and neck with perineural spread. Cancer Med. 2024 Aug;13(16):e70118. doi: 10.1002/cam4.70118.

Ebrahimi A, Gupta R, McDowell L, Magarey MJR, Smith PN, Schulte KM, Perriman DM, Veness M, Porceddu S, Low TH, Fowler A, Clark JR. Determinants of Prognosis in Head and Neck Cutaneous Squamous Cell Carcinoma With Nodal Metastases. JAMA Otolaryngol Head Neck Surg. 2024 Nov 1;150(11):986-994. doi: 10.1001/jamaoto.2024.3103.

Goutaki M, Lam YT, Anagiotos A, Armengot M, Burgess A, Campbell R, Carlier M, Caversaccio N, Chadha NK, Demir B, Dheyauldeen SAD, Gunaydin O, Harris A, Hayn I, Inal-Ince D, Levi E, Fernandez TL, Lucas JS, Maitre B, Poirrier AML, Schofield L, Takeuchi K, van Gogh C, Wolter NE, Papon JF. Definition of sinonasal and otological exacerbation in patients with primary ciliary dyskinesia: an expert consensus. ERJ Open Res. 2024 Dec 16;10(6):00218-2024. doi: 10.1183/23120541.00218-2024.

Ferguson AL, Beddow T, Patrick E, Willie E, Elliott MS, Low TH, Wykes J, Hui MH, Palme CE, Boyer M, Clark JR, Lee JH, Palendira U, Gupta R. Spatial mapping reveals unique cellular interactions and enhanced tertiary lymphoid structures in responders to anti-PD-1 therapy in mucosal head and neck cancers. bioRxiv. 2024 Apr 18. doi: 10.1101/2024.04.18.590189.

Hayler R, Hussain G, Clark J, Coulson S, Low TH (Hubert). Botulinum toxin application to the buccinator muscle in the treatment of facial synkinesis: a prospective cohort study. AJOPS. 2024;7(2). doi:10.34239/ajops.91851.

Hayler R, Long LE, Charters E, Hussain G, Ngo Q, Tulumuri K et al. Utility of telehealth for multidisciplinary assessment and management of patients with facial nerve palsy. Australian Journal of Otolaryngology. 2024 Jun 30;7:1-8. 22. doi: 10.21037/ajo-24-5.

Ho J, Walter S, Alvarado R, Grayson JW, Campbell RG, Kalish LH et al. Clinical features of responders to mepolizumab in eosinophilic chronic rhinosinusitis and the outcomes post treatment cessation. Australian Journal of Otolaryngology. 2024 Apr 15;7:1-14. 17. doi: 10.21037/ajo-23-28.

Jackson L, Charters E, Dunn M, Clark J, Low TH. Trismus following facial nerve sacrifice and reanimation surgery: incidence and management. Oral Oncol Rep. 2024;12:100658. doi:10.1016/j.oor.2024.100658.

Khoo AL, Clark JR, Low TH, Wykes J, Ch’ng S, Elliott M. Functional and aesthetic outcomes of dermofat graft reconstruction in limited parotidectomy defects: a cross-sectional study. Aust J Otolaryngol 2024;7:13.

Mooney CP, Reddy R, Saxby A, Jufas N, Kong JHK, Patel N. Endoscopic management of acquired paediatric cholesteatoma: a retrospective cohort study. Australian Journal of Otolaryngology. 2024 Jul 30;7:1-8. 27. doi: 10.21037/ajo-23-53.

Ryan P, Campbell RG, Morgan LC. Describing the ear, nose, and throat symptom burden in a cohort of Australian patients with primary ciliary dyskinesia. Australian Journal of Otolaryngology. 2024 Dec 30;7:1-11. 41. doi: 10.21037/ajo-24-6.

Saxby AJ, Schofield D, Tout F, Gordon J, Verkerk MM, Watson T et al. The Earphone Project pilot: a tele-otology study for remote Aboriginal communities. Australian Journal of Otolaryngology. 2024 Oct 30;7:1-11. 38. Epub 2024 Sept 1. doi: 10.21037/ajo-23-59.

2023

Argaet EC, Kwok BYC, Bradley J, Young AS, Nham B, Calic Z, Taylor RL, Pogson JM, Reid N, Kong JHK, Flanagan S, Halmagyi GM, Rosengren SM, Welgampola MS. Subjective visual horizontal correlates better with ocular than with cervical vestibular evoked myogenic potentials. Clin Neurophysiol. 2023 Aug;152:1-10. doi: 10.1016/j.clinph.2023.04.011. Epub 2023 May 12.

Campbell RG, Auyeung T, Katsoulotos GP. Pulmonology for the rhinologist. Curr Opin Otolaryngol Head Neck Surg. 2024 Feb 1;32(1):20-27. doi: 10.1097/MOO.0000000000000944. Epub 2023 Nov 15.

Campbell RG, Douglas RG, Zadro J, Gamble A, Chan CL, Mackey MG, Pappas E. Don't Just Stand There. Rethinking the Ideal Body Posture for Otorhinolaryngologists. Ann Otol Rhinol Laryngol. 2024 Mar;133(3):355-362. doi: 10.1177/00034894231214035. Epub 2023 Dec 3.

Fung YY, Chung D, Clark JR, Low TH, Palme CE, Wykes J, Elliott MS. Comparative analysis of pre-operative ultrasound and histopathology in small papillary thyroid carcinoma in the era of active surveillance. ANZ J Surg. 2023 Apr;93(4):902-906. doi: 10.1111/ans.18353. Epub 2023 Feb 28.

Jafari A, Adappa ND, Anagnos VJ, Campbell RG, Castelnuovo P, Chalian A, Chambers CB, Chitguppi C, Dallan I, El Rassi E, Freitag SK, Fernandez Miranda JC, Ferreira M Jr, Gardner PA, Gudis DA, Harvey RJ, Huang Q, Humphreys IM, Kennedy DW, Lee JYK, Lehmann AE, Locatelli D, McKinney KA, Moreau A, Nyquist G, Palmer JN, Prepageran N, Pribitkin EA, Rabinowitz MR, Rosen MR, Sacks R, Sharma D, Snyderman CH, Tonya Stefko S, Stokken JK, Wang EW, Workman AD, Wu AW, Yu JY, Zhang MM, Zhou B, Bleier BS. Orbital resection by intranasal technique (ORBIT): A new classification system for reporting endoscopically resectable primary benign orbital tumors. Int Forum Allergy Rhinol. 2023 Oct;13(10):1852-1863. doi: 10.1002/alr.23141. Epub 2023 Mar 2.

Kwok BYC, Young AS, Kong JHK, Birman CS, Flanagan S, Greenberg SL, Gibson WP, Argaet EC, Fratturo L, Pogson JM, Taylor RL, Rosengren SM, Halmagyi GM, Welgampola MS. Post Cochlear Implantation Vertigo: Ictal Nystagmus and Audiovestibular Test Characteristics. Otol Neurotol. 2024 Jan 1;45(1):65-74. doi: 10.1097/MAO.0000000000004037. Epub 2023 Oct 14.

Manzie T, Howes D, Leinkram D, Fleming S, Clark JR, Dunn M, Elliott M, Low TH. Virtual surgical planning for combined nasal, dental and maxillary reconstruction with the prefabricated fibula flap. Oral Oncol. 2023 Jan;136:106264. doi: 10.1016/j.oraloncology.2022.106264. Epub 2022 Nov 28.

Osie G, Darbari Kaul R, Alvarado R, Katsoulotos G, Rimmer J, Kalish L, Campbell RG, Sacks R, Harvey RJ. A Scoping Review of Artificial Intelligence Research in Rhinology. Am J Rhinol Allergy. 2023 Jul;37(4):438-448. doi: 10.1177/19458924231162437. Epub 2023 Mar 9.

Papanikolas MJ, Hurrell MJL, Clark JR, Low TH, Ch'ng S, Elliott MS, Palme CE, Wykes J. Anterolateral thigh, radial forearm and superficial circumflex iliac perforator flaps in oral reconstruction: a comparative analysis. ANZ J Surg. 2023 May;93(5):1335-1340. doi: 10.1111/ans.18239. Epub 2023 Jan 11.

Rom D, Sit A, Alvarado R, Earls P, Rimmer J, Campbell R, Kalish L, Sacks R, Harvey RJ. Bacterial colonization differences between central compartment atopic disease and eosinophilic chronic rhinosinusitis. Int Forum Allergy Rhinol. 2023 Oct;13(10):1978-1981. doi: 10.1002/alr.23155. Epub 2023 Mar 23.

Seresirikachorn K, Png LH, Kondo M, Kalish L, Campbell RG, Alvarado R, Harvey RJ. Endoscopic-Modified Medial Maxillectomy for the Nonfunctioning Maxillary Sinus. Am J Rhinol Allergy. 2023 Sep;37(5):611-615. doi: 10.1177/19458924231175848. Epub 2023 May 14.

Seresirikachorn K, Sit A, Png LH, Kalish L, Campbell RG, Alvarado R, Harvey RJ. Carolyn's Window Approach to Unilateral Frontal Sinus Surgery. Laryngoscope. 2023 Oct;133(10):2496-2501. doi: 10.1002/lary.30569. Epub 2023 Jan 18.

Sit A, Alvarado R, Earls P, Rimmer J, Kalish L, Campbell R, Sewell W, Harvey RJ. CCAD or eCRS: Defining Eosinophilic Subpopulations in Chronic Rhinosinusitis. Am J Rhinol Allergy. 2023 Jul;37(4):402-409. doi: 10.1177/19458924231155012. Epub 2023 Feb 5.

Sit A, Seresirikachorn K, Zhang AS, Mangussi-Gomes J, Kanjanawasee D, Png LH, Kalish L, Campbell RG, Alvarado R, Harvey RJ. Recreating the microscopic direct access Draf 2a frontal sinusotomy in the endoscopic era and comparison to an angled instrument approach. Eur Arch Otorhinolaryngol. 2023 Dec;280(12):5353-5361. doi: 10.1007/s00405-023-08098-3. Epub 2023 Jul 7.

Treble A, Do T, Sarkis L, Newey A, Naidoo SY, Saxby A, Kong J, Patel NP, Jufas N. Caution in Transnasal Balloon Dilation of the Eustachian Tube: Middle Ear Penetration of Catheter Tip in a Cadaveric Model. Otol Neurotol. 2023 Mar 1;44(3):241-245. doi: 10.1097/MAO.0000000000003802. Epub 2023 Jan 8.

Wise SK, Damask C, Roland LT, Ebert C, Levy JM, Lin S, Luong A, Rodriguez K, Sedaghat AR, Toskala E, Villwock J, Abdullah B, Akdis C, Alt JA, Ansotegui IJ, Azar A, Baroody F, Benninger MS, Bernstein J, Brook C, Campbell R, Casale T, Chaaban MR, Chew FT, Chambliss J, Cianferoni A, Custovic A, Davis EM, DelGaudio JM, Ellis AK, Flanagan C, Fokkens WJ, Franzese C, Greenhawt M, Gill A, Halderman A, Hohlfeld JM, Incorvaia C, Joe SA, Joshi S, Kuruvilla ME, Kim J, Klein AM, Krouse HJ, Kuan EC, Lang D, Larenas-Linnemann D, Laury AM, Lechner M, Lee SE, Lee VS, Loftus P, Marcus S, Marzouk H, Mattos J, McCoul E, Melen E, Mims JW, Mullol J, Nayak JV, Oppenheimer J, Orlandi RR, Phillips K, Platt M, Ramanathan M Jr, Raymond M, Rhee CS, Reitsma S, Ryan M, Sastre J, Schlosser RJ, Schuman TA, Shaker MS, Sheikh A, Smith KA, Soyka MB, Takashima M, Tang M, Tantilipikorn P, Taw MB, Tversky J, Tyler MA, Veling MC, Wallace D, Wang Y, White A, Zhang L. International consensus statement on allergy and rhinology: Allergic rhinitis - 2023. Int Forum Allergy Rhinol. 2023 Apr;13(4):293-859. doi: 10.1002/alr.23090. Epub 2023 Mar 6.

Wong EH, Cavada MN, Orgain CA, Grayson JW, Alvarado R, Campbell RG, Harvey R, Sacks R, Kalish LH. The Modified Medial Maxillectomy as a Radical or Extended,-yet Still Functional,-Technique in Sinus Surgery. Am J Rhinol Allergy. 2023 Jul;37(4):476-484. doi: 10.1177/19458924231168219. Epub 2023 Apr 19.

Zhang AS, Jonker BP, Morris CL, Campbell RG, Alvarado R, Winder M, Sacks R, Seresirikachorn K, Harvey RJ. Endoscopic Endonasal Biopsy for Diagnosis of Undifferentiated Lesions of the Cavernous Sinus. World Neurosurg. 2023 Jul;175:e391-e396. doi: 10.1016/j.wneu.2023.03.103. Epub 2023 Mar 31.

Zhang M, Phung D, Gupta R, Wykes J, Wu R, Lee J, Elliott M, Palme CE, Clark J, Low TH. Persisting facial nerve palsy or trigeminal neuralgia - red flags for perineural spread of head and neck cutaneous squamous cell carcinoma (HNcSCC). ANZ J Surg. 2023 Oct;93(10):2394-2401. doi: 10.1111/ans.18625. Epub 2023 Jul 23.

2022

Briggs R, CS Birman, N Baulderstone, AT Lewis, IHY Ng, A Östblom, A Rousset, S Tari, MCF Tong, Robert Cowan, Clinical Performance, Safety, and Patient-Reported Outcomes of an Active Osseointegrated Steady-State Implant System Otol Neurotol 43 (7), 827-834.

Cheung LL, Kong J, Chu PY, Sanli H, Walton J, Birman CS. Misplaced Cochlear Implant Electrodes Outside the Cochlea: A Literature Review and Presentation of Radiological and Electrophysiological Findings. Otol Neurotol. 2022 Jun 1;43(5):567-579. doi: 10.1097/MAO.0000000000003523. Epub 2022 Mar 8.

Cheung MMY, Tsang TW, Watkins R, Birman C, Popova S, Elliott EJ. Ear Abnormalities Among Children with Fetal Alcohol Spectrum Disorder: A Systematic Review and Meta-Analysis.J Pediatr. 2022 Mar;242:113-120.e16. doi: 10.1016/j.jpeds.2021.11.016. Epub 2021 Nov 13.

Cosway B, Fussey J, Kim D, Wykes J, Elliott M, Smith J. Sporadic Medullary Thyroid Cancer: A Systematic Review and Meta-Analysis of Clinico-Pathological and Mutational Characteristics Predicting Recurrence. Thyroid Res. 2022 Jul 22;15(1):12.

Creber NJ, Eastwood HT, Hampson AJ, Lo J, Zhang D, Chambers S, Bester CW, Thorne PR, O'Leary SJ.. Spironolactone Ameliorates Cochlear Implant Induced Endolymphatic Hydrops. Otology & Neurotology 43(6):p 685-693, July 2022.

Deutsch F, Bullen IR, Nguyen K, Tran N-G, Elliott MS, Tran N. Current state of play for HPV-positive oropharyngeal cancers. Cancer Treat Rev. 2022 Nov;110:102439.

Hannigan, I.P., Rosengren S.M., Young A.S., Bradshaw, A.P., Calic Z., Kwok B, Alraddy B, Gibson W.P.R, Kong J.H., Flanagan S, Halmagyi G.M., Watson S.R.D., Welgampola M.S. A Portrait of Menière's Disease Using Contemporary Hearing and Balance Tests. Otol Neurotol 2022 43(4):e489-e496.

Ho J, Rimmer J, Sewell W, Earls P, Alvarado R, Walker S, Campbell RG, Sacks R, Kalish LH, Harvey RJ. Comparison of sinonasal histopathological changes in biological treatment of eosinophilic chronic rhinosinusitis. American Journal of Rhinology & Allergy 2022;36(1):72-80. doi: 10.1177/19458924211021031.

Hulme KR, Mahar A, Campbell RG, Clifton-Bligh R, Palme CE, Gupta R. Phosphaturic Mesenchymal Tumours in the Head and Neck: Report of three cases and review of literature. Head and Neck Pathology. Vol.:(0123456789)1 https://doi.org/10.1007/s12105-022-01419-8.

Hurrell M, Heller G, Elliott MS, Gao K, Ebrahimi A, Clark JR, Shannon K, Palme CE, Wykes J, Gupta R, Ch'ng S, Nguyen K, Low T-H. Recursive Partitioning to Determine Order of Significance of Regional Metastasis Characteristics in Head and Neck Cutaneous Squamous Cell Carcinoma. Ann Surg Oncol. 2022 Oct;29(11):7000-7001.

Irawati N, Moghadam A, Abdul-Razak M, Strach M, Elliott MS, Ch'ng S, Shannon K, Palme CE, Clark JR, Wykes J, Low T-H. Outcomes after definitive treatment for head and neck angiosarcoma. ANZ J Surg. 2022 Jun;92(6):1407-1414.

Kwok BYC, Rosengren SM, Kong JHK, Birman CS, Hoskisson E, Young AS, Argaet EC, Fratturo L, Rivas C, Greenberg SL, Saxby AJ, Welgampola MS Impact of Cochlear Implantation on Canal and Otolith Function.Otol Neurotol. 2022 Mar 1;43(3):304-312. doi: 10.1097/MAO.0000000000003459.

Lee V, Patel P, O'Brien D, Scangas G, Campbell R, Chandra R, Davis G, Han J, Le C, Lee J, Luong A, Poetker D, Ramadan H, Setzen M, Smith K, Wise S, Villwock J, Ference E. Indications for Absorbable Steroid-Eluting Sinus Implants: Viewpoint via the Delphi Method. Int Forum Allergy Rhinol 2022. doi: 10.1002/alr.23044

Lee, M. F. H., & Ananda, A. (2022). Self-assembling RADA16 peptide hydrogel supports hemostasis, synechiae reduction, and wound healing in a sheep model of endoscopic nasal surgery [Article]. Auris Nasus Larynx. https://doi.org/10.1016/j.anl.2022.09.012.

Mehta N, Chu P, Birman CS To Use the Back-up Cochlear Implant or Not? Using Intra-operative Impedance to Guide Your Decisions. Otol Neurotol. 2022 Mar 2. doi: 10.1097/MAO.0000000000003483. Online ahead of print.

Nandakumar, B. S., Mukherjee, P., Yung, A. E., Nirmalananda, A., & Ch'ng, S. (2022). Grafts in septorhinoplasty: a systematic review and future directions [Review]. Australian Journal of Otolaryngology, 5, Article 28. https://doi.org/10.21037/ajo-22-12.

O'Leary S, Mylanus E, Venail F, Lenarz T, Birman C, Di Lella F, Roland JT Jr, Gantz B, Beynon A, Sicard M, Buechner A, Lai WK, Boccio C, Choudhury B, Tejani VD, Plant K, English R, Arts R, Bester C. "Monitoring Cochlear Health With Intracochlear Electrocochleography During Cochlear Implantation: Findings From an International Clinical Investigation" Ear Hear. 2022 Nov 8.

Osie G, Wegreckim K, Alvarado R, Campbell RG, Kalish L, Rimmer J, Sacks R, Harvey RH. Features of inhalant allergy on nasal endoscopy: a systematic review and meta-analysis. Rhinology 2022.

Perkovic A, Ho J, Kanjawasee D, Alvarado R, Rimmer J, Kalish LH, Campbell RG, Sacks R, Harvey RJ. Age of presentation as a distinguishing feature between persistent rhinitis and chronic rhinosinusitis. Int Forum Allergy Rhinol 2022;12:217-219.

Phung D, Fradet L, Riffat F, Novakovic D, Elliott MS, Nguyen K, Makeham J, Palme CE. Translaryngeal Ultrasound in Thyroid Surgery - State of the Art Review. ANZ J Surg. 2022 Mar;92(3):385-389.

Phung D, Navid Amadi, Ruta Gupta, Jonathan Clark, James Wykes, Sydney Ch'ng, Carsten Palme, Kerwin Shannon, Raymond Wu, Jenny Lee, Tsu-Hui Hubert Low. Survival outcomes of perineural spread in head and neck cutaneous squamous cell carcinoma. ANZ J Surg. 2022 Sep;92(9):2299-2304.

Pogson, J. M., Taylor R.L., Bradshaw A.P., McGarvie L., D'Souza M., Flanagan S., Kong J.H., Biggs N., Shivalingam B., Greenberg S., Croxson G., Halmagyi G.M., Welgampola M.S. et al. The human vestibulo-ocular reflex and compensatory saccades in schwannoma patients before and after vestibular nerve section. Clin Neurophysiol (2022) doi:10.1016/j.clinph.2022.02.014.

Sacks PL, Kalish LH. Campbell RG, Sacks R, Harvey RH. Prognostic factors and outcomes in minimal access resections of skull base and sinonasal epithelial malignancy. ANZ J Surgery 2022;92(12):3253-3258.

Seresirikachorn K, Kalish L, Kondo M, Png L, Campbell RG, Alvarado R, Harvey RH. Prelacrimal approach to maxillary sinus pathology. Am J Rhinol Allergy 2022;37(3):369-373.

Sit A, Alvarado R, Earls P, Rimmer J, Kalish L, Campbell R, Sewell W, Harvey R. Defining eosinophilic subpopulations in chronic rhinosinusitis. Am J Rhinol Allergy 2022.

Walter S, Ho J, Alvarado R, Grayson J, Earls P, Rimmer J, Kalish LH, Sacks R, Gomes JP, Campbell RG, Harvey RH. Mepolizumab decreases tissue eosinophils while increasing type-2 cytokines in eosinophilic chronic rhinosinusitis. Clinical and Experimental Allergy 2022;52(12):1403-1413.

Wong WK, Lee MF, Saxby AJ Giant Cholesteatoma: A Case Report and Review of the Literature. Otol Neurotol. 2022 Jul 1;43(6):e658-e622.

Yung A, Crouch G, Varey A, Lo S, Elliott MS, Lee J, Rawson R, Gupta R, Hong A, Clark JR, Ch'ng S. Benchmarking Survival Outcomes Following Surgical Management of pT3 and pT4 Cutaneous Squamous Cell Carcinoma of the Head and Neck. Ann Surg Oncol. 2022 Aug;29(8):5124-5138.

2021

Aw GE, Parker GD, Halmagyi GM, Saxby AJ. Pulsatile Tinnitus in Superior Semicircular Canal Dehiscence Cured by Endovascular Coil Occlusion of the Superior Petrosal Sinus. Otol Neurotol. 2021 Jun 1;42(5):e629-e630.

Campbell RG, Harvey RJ. How close are we to robotic anterior skull base surgery??Current Opinion in Otolaryngology 2021;29(1):44-52.

Campbell RG. Sinonasal surgery in children. Invited paper. Australian Journal of Otolaryngology 2021 Volume 4 September.

Cheng H, Saxby A, Jufas N, Kong J, Patel N. Balloon dilation eustachian tuboplasty for dilatory dysfunction: Safety and efficacy analysis in an Australian cohort. ANZ J Surg. 2021 Jun 1;91:1480-1484.

Cheung, P. K. F., Walton, J., Hobson, M. L., Taylor, P., Chin, M., Boardman, S., Cheng, A. T. L. & Birman, C. S., Management of recurrent and delayed post-tonsillectomy and adenoidectomy haemorrhage in children Ear Nose and Throat Journal 9 Mar 2021.

COVIDSurg Collaborative. Elective Cancer Surgery in COVID-19-Free Surgical Pathways During the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study. J Clin Oncol. 2021 Jan 1;39(1):66-78.

COVIDSurg Collaborative. Preoperative nasopharyngeal swab testing and postoperative pulmonary complications in patients undergoing elective surgery during the SARS-CoV-2 pandemic. British Journal of Surgery, Volume 108, Issue 1, January 2021, Pages 88-96.

Dawson R, Phung D, Every J, Gunawardena D, Low TH, Ch'ng S, Clark J, Wykes J, Palme CE. Tracheostomy in free-flap reconstruction of the oral cavity: can it be avoided? A cohort study of 187 patients. ANZ J Surg. 2021 Jun;91(6):1246-1250. doi: 10.1111/ans.16762. Epub 2021 Apr 6.

Every J, Subramaniam N, Dawson R, Ch'ng S, Low TH, Palme CE, Clark J, Wykes J.Microvascular reconstruction of head and neck defects in the elderly. ANZ J Surg. 2021 May;91(5):969-974. doi: 10.1111/ans.16771. Epub 2021 Apr 6.

Habib AR, Kalish L, Alvarado R, Campbell RG, Grayson J, Sacks R, Harvey RJ. The association between body size and chronic upper airway disorders in Australia. Am J Otolaryngol Head Neck Surg. Australian Journal of Otolaryngology 2021;4:4-9.

Haymerle G, Charters EK, Froggatt C, Wykes J, Palme CE, Clark JR.Transoral robotic free flap inset in oropharyngeal cancer. Clin Otolaryngol. 2021 May;46(3):642-644. doi: 10.1111/coa.13696. Epub 2021 Jan 9.

Hensen L, Illing P, Clemens E, Nguyen T, Koutsakos M, van de Sandt C, Mifsud N, Nguyen A, Szeto C, Chua B, Halim H, Rizzetto S, Luciani F, Loh L, Grant E, Saunders P, Brooks A, Rockman S, Kotsimbos T, Cheng A, Richards M, Westall G, Wakim L, Loudovaris T, Mannering S, Elliott M, Tangye S, Jackson D, Flanagan K, Rossjohn J, Gras S, Davies J, Miller A, Tong S, Purcell A, and Kedzierska K. CD8+ T cell landscape in Indigenous and non-Indigenous people restricted by influenza mortality-associated HLA-A*24:02 allomorph. Nature communications. Volume 12, Issue 1. 2021 May 5.

Hoskison E, Harrop E, Jufas N, Kong J, Patel N, Saxby A. Endoscopic Stapedotomy: A Systematic Review. Otol Neurotol 2021 Dec 1;42(10)e1638-e1643.

Jabbour J, Shepherd HL, Beddow T, Sundaresan P, Milross C, Palme CE, Clark JR, Dhillon HM. Assessment of an evidence-based laryngeal cancer fact sheet: A mixed methods study. Health Informatics J. 2021 Jan-Mar;27(1):1460458221989403. doi: 10.1177/1460458221989403.

Kanjanawasee D, Campbell RG, Rimmer J, Alvarado R, Kanjanaumporn J, Snidvongs K, Kalish L, Harvey RJ, Sacks R. Empty nose syndrome pathophysiology: a systematic review. Otolaryngology Head and Neck Surgery 2021. DOI: 10.1177/01945998211052919

Katelaris C, Sacks R, Harvey RJ, Campbell RG, Lucas M, Pratchett K, Rimmer J, Smith W. Australian Society of Clinical Immunology and Allergy (ASCIA) Position Statement on Chronic Rhinosinusitis with Nasal Polyposis. https://www.allergy.org.au/hp/papers/crswnp. 

Lazim NM, Elliott M, Wykes J, Clark J. Oligometastases in head and neck carcinoma and their impact on management. ANZ J Surg. 2021 Feb 26.

Li W, Ho J, Grayson JW, Alvarado R, Rimmer J, Sewell WA, Campbell R, Kalish L, Sacks R, Harvey RJ. Evaluation of diffuse type 2 dominant or eosinophilic chronic rhinosinusitis with corticosteroid irrigation after surgical neosinus cavity formation. JAMA Otolaryngol Head Neck Surg 2021;147(4)360-367.

Luk PP, Ebrahimi A, Veness MJ, McDowell L, Magarey M, Gao K, Palme CE, Clark JR, Gupta R. Prognostic value of the 8th edition American Joint Commission Cancer nodal staging system for patients with head and neck cutaneous squamous cell carcinoma: A multi-institutional study. Head Neck. 2021 Feb;43(2):558-567. doi: 10.1002/hed.26512. Epub 2020 Oct 29.

Ma AK, Saxby, A, Kong J, Patel N, Jufas, N. Endoscopic ear surgery in Australia. Australian J Otolaryngology 2021;4, 6-6.

Mirian C, Gerds TA, Pedersen MM, de Ridder M, Balm A, Mattavelli D, Piazza C, Jensen LR, Balasubramanian D, Subramaniam N, Dokhe Y, Thankappan K, Iyer S, Karam SD, Wiegand S, Feeley L, Milross C, Gao K, Palme CE, Low TH, Gupta R, Freudlsperger C, Moratin J, Sheahan P, Clark J, Ovesen T. Metrics of pN-staging in oral squamous cell carcinoma: An analysis of 1,905 patients. Eur J Cancer. 2021 Jun;150:33-41. doi: 10.1016/j.ejca.2021.03.019. Epub 2021 Apr 19.

Mooney C, Clark J, Shannon K, Palme C, Ebrahimi A, Gao K, Ch'ng S, Elliott M, Gupta R, Low TS. The significance of regional metastasis location in head and neck cutaneous squamous cell carcinoma. Head Neck. 2021 Sep;43(9):2705-2711.

Mooney CP, Clark JR, Shannon K, Palme CE, Ebrahimi A, Gao K, Ch'ng S, Elliott M, Gupta R, Low TH. The significance of regional metastasis location in head and neck cutaneous squamous cell carcinoma. Head Neck. 2021 Sep;43(9):2705-2711. doi: 10.1002/hed.26744. Epub 2021 May 21.

Mooney CP, Gao K, Clark JR, Gupta R, Shannon K, Palme CE, Ebrahimi A, Ch'ng S, Low TH. Soft Tissue Metastases in Head and Neck Cutaneous Squamous Cell Carcinoma. Laryngoscope. 2021 Apr;131(4):E1209-E1213. doi: 10.1002/lary.29064. Epub 2020 Sep 14.

Oh LJ, Asher R, Veness M, Smee R, Goldstein D, Gopalakrishna Iyer N, Balasubramanian D, Low TH, Palme CE, Gupta R, Clark J. Effect of age and gender in non-smokers with oral squamous cell carcinoma: Multi-institutional study. Oral Oncol. 2021 May;116:105210. doi: 10.1016/j.oraloncology.2021.105210. Epub 2021 Feb 19.

Oh LJ, Satgunaseelan L, Asher R, Veness M, Smee R, Goldstein D, Gopalakrishna Iyer N, Balasubramanian D, Low H, Palme CE, Gupta R, Clark JR. Young age is not a predictor of disease specific survival in oral cancer: A multi-institutional study. Oral Oncol. 2021 Apr;115:105162. doi: 10.1016/j.oraloncology.2020.105162. Epub 2021 Feb 3.

Percovic A, Campbell RG, Kalish LH, Sacks R, Harvey RJ. Age of presentation as a distinguishing feature between persistent rhinitis and chronic rhinosinusitis. Int For Allergy Rhinol 2021. DOI 10.1002/alr.22881.

Petrides GA, Hicks G, Dunn M, Froggatt C, Wallace C, Howes D, Leinkram D, Low TH, Ch'ng S, Wykes J, Palme CE, Clark JR.Dentoalveolar outcomes in maxillary reconstruction: A retrospective review of 85 maxillectomy reconstructions. ANZ J Surg. 2021 Jul;91(7-8):1472-1479. doi: 10.1111/ans.17001. Epub 2021 Jun 14.

Quick M, Acharya A, Friedland P, Kong J, Saxby A, Patel N, Kadhim L. Endoscopic Management of Early Stage Middle Ear Paragangliomas - An Australian Case Series. Otol Neurotol 2021 Dec 1;42(10):e1677-e1682.

Rao, A. et al. Endoscopic management of en-plaque cholesteatoma associated with tympanic membrane perforations. Australian J Otolaryngology 2021; :35-35.

Razi B, Percovic A, Alvarado R, Stroud A, Ho J, Kalish LH, Campbell RG, Sacks R, Harvey RJ. Sinus radiological findings in general asymptomatic populations: a systematic review of incidental mucosal changes. Otolaryngol Head Neck Surg 2021.?DOI:?10.1177/01945998211035097

Razi B, Perkovic A, Alvarado R, Stroud A, Ho J, Kalish LH, Campbell RG, Sacks R, Harvey RJ. Sinus Radiological Findings in General Asymptomatic Populations: A systematic review of incidental mucosal changes. Otolaryngol Head Neck Surg. 2021 Aug.

Ridge SE, Chari DA, Kozin ED, Remenschneider AK, Adunka OF, Aristegui M, Chang WT, Cheng YF, Chung JW, Cohen MS, Crowson MG, Golub JS, Handzel O, Isaacson B, Iyer A, Kakehata S, Marchioni D, Nogueira JF, Patel N, Quesnel AM, Rivas A, Saeed SR, Salzman R, Santos F, Saxby AJ, Tarabichi M, Verhaert N, Vincent R, Wanna G, Wolpert S, Lee DJ. International Survey of Operative Practices for Otologists and Neurotologists During the COVID-19 Crisis. Otol Neurotol 2021 Sep 1;42(8):1275-1284.

Satgunaseelan L, Porazinski S, Strbenac D, Istadi A, Willet C, Chew T, Sadsad R, Palme CE, Lee JH, Boyer M, Yang JYH, Clark JR, Pajic M, Gupta R. Oral Squamous Cell Carcinoma in Young Patients Show Higher Rates of EGFR Amplification: Implications for Novel Personalized Therapy. Front Oncol. 2021 Nov 29;11:750852. doi: 10.3389/fonc.2021.750852. eCollection 2021.

Saxby AJ, Jufas N, Kong JHK, Newey A, Pitman AG, Patel NP. Novel Radiologic Approaches for Cholesteatoma Detection: Implications for Endoscopic Ear Surgery. Otolaryngol Clin North Am. 2021 Feb;54(1):89-109.

Smithers FAE, Haymerle G, Palme CE, Low TH, Froggatt C, Gupta R, Clark JR. A prospective study of intraoperative assessment of mucosal squamous cell carcinoma margins in the head and neck. Head Neck. 2021 Feb;43(2):590-600. doi: 10.1002/hed.26517. Epub 2020 Oct 23.

Subramaniam N, Palme CE, Low TH. Combined approach for malignant tumours of the deep lobe of the parotid involving the stylomandibular tunnel and parapharyngeal space. Oral Oncol. 2021 Aug;119:105283. doi: 10.1016/j.oraloncology.2021.105283. Epub 2021 Apr 26.

Tjahjono R, Nguyen K, Phung D, Riffat F, Palme CE.Methods of identification of parathyroid glands in thyroid surgery: A literature review. ANZ J Surg. 2021 Sep;91(9):1711-1716. doi: 10.1111/ans.17117. Epub 2021 Aug 20.

Tjahjono R, Phung D, Gurney H, Gupta R, Riffat F, Palme CE. Thyroid gland metastasis from renal cell carcinoma: a case series and literature review. ANZ J Surg. 2021 Apr;91(4):708-715. doi: 10.1111/ans.16482. Epub 2020 Dec 14.

van Sluis KE, van Son RJJH, van der Molen L, MCGuinness AJ, Palme CE, Novakovic D, Stone D, Natsis L, Charters E, Jones K, Dirven R, van den Brekel MWM. Multidimensional evaluation of voice outcomes following total laryngectomy: a prospective multicenter cohort study. Eur Arch Otorhinolaryngol. 2021 Apr;278(4):1209-1222. doi: 10.1007/s00405-020-06216-z. Epub 2020 Jul 21.

Watkins T, Miles J, Elliott M, Sierro F, Feng C, Britton W, Gebhardt T, Tangye S, Palendira U. Tissue-resident regulatory T cells accumulate at human barrier lymphoid organs. Immunology & Cell Biology 3rd June 2021.

Watts F, Palme CE, Porceddu S, Sundaresan P, Clark JR, Gupta R. Clinician perspectives on the factors influencing prognostic stratification by the American Joint Commission on Cancer Head and Neck Cutaneous Squamous Cell Carcinoma Staging. Surgery. 2021 Nov;170(5):1467-1473. doi: 10.1016/j.surg.2021.04.019. Epub 2021 Jun 12.

2020

Birman CS, Sanli H. Cochlear Implant Outcomes in Patients With Severe Compared With Profound Hearing Loss. Otol Neurotol. 2020 Apr;41(4):e458-e463.

Briggs R, O 'Leary S, Birman C, Plant K, English R, Dawson P, Risi F, Gavrilis J, Needham K, Cowan R. Comparison of electrode impedance measures between a dexamethasone-eluting and standard Cochlear™ Contour Advance® electrode in adult cochlear implant recipients. Hear Res. 2020 May;390:107924.

Campbell RG. SARS-CoV-2 and the nose: risks and implications for primary care. Aust J Gen Pract 2020;49(11):728-732.

Cavada MN, Wong E, Orgain CA, Grayson JW, Alvarado R, Campbell RG, Kalish LH, Harvey RJ. Fungal ball of the maxillary sinus and the risk of persistent sinus dysfunction after simple antrostomy. Am J Otolaryngol 2020;41(4):102541.

Ma SW, Ende JA, Alvarado R, Christensen JM, Kalish L, Sacks R, Campbell RG, Rimmer J, Harvey RJ. Topical vitamin D may modulate human sinonasal mucosal responses to house dust mite antigen. Am J Rhinol Allergy 2020;334(4):471-481.

Matifoll P, Wilson J-A, Goetti R, Birman C, Peadon E, Prtats-Uribe A, Prelog K. A case series of X-linked deafness-2 with sensorineural hearing loss, stapes fixation and perilympahtic gusher: MR imaging and clinical features of hypothalamic malformations. Am J of Neuroradiology (2020 41, 6, p1087-1093.

Mukherjee P, Cheng K, Wallace G, Chiaravano E, Macdougall H, O'Leary S, Solomon M. 20year review of 3 Dimensional tools in Otology: challenges of translation and innovation. Otology and Neurotology. 2020; 41(5): 589-595.

Mukherjee P, Chung J, Cheng K, Gupta R, Haag H, Williams Z, Wallace G. Invitro and invivo study of PCL-Hydrogel scaffold: degradation pattern and biological response. Journal of Craniofacial Surgery. Nov 2020: DOI: 10.1097/SCS.0000000000007173

Rubini A, Jufas N, Marchioni D, Saxby AJ, Kong JHK, Patel NP. The Endoscopic Relationship of the Stapedius Muscle to the Facial Nerve: Implications for Retrotympanic Surgery. Otol Neurotol. 2020 Jan;41(1):e64-e69.

Toner FM, Sanli H, Hall AC, Birman CS. Intraoperative cochlear implant reinsertion effects evaluated by electrode impedance. Otology Neurotol July 2020 41, 6, pp e695-699.

Vaughan C, Fox R, Jufas N, Kong JHK, Patel NP, Saxby AJ. Endoscopic Stapedectomy: Collective Experience From a Large Australian Center. Otol Neruotol. 2020 Jul 27.

Walter S, Ho J, Alvarado R, Rimmer J, Campbell R, Kalish L, Sacks R, Harvey RJ. Effect of monoclonal antibody drug therapy on mucosal biomarkers in airway disease: a systematic review. American Journal of Otolaryngology 2020;41(4):102541.

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