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Renal Medicine Research

Selected Grants

Amount awarded	Grant and project details
$5,522,418	NHMRC Project Grant, 2019-2024 Treatment of cardiovascular disease with very low dose Rivaroxaban in Advanced Chronic Kidney disease (The TRACK Trial) Investigator: Jardine M (CIC)
$4,353,258	NHMRC CTCS Project Grant, 2020-2024 Evaluation of the efficacy and safety of health service dialysate sodium practice on clinical outcomes Investigator: Jardine M (CIA)
$2,191,749	MRFF Project Grant, 2019-2023 Better Evidence and Treatment for Calciphylaxis (BEAT-Calci) Investigator: Jardine M

Our Publications

2023

Barratt J, Rovin B, Wong MG, Alpers CE, Bieler S, He P, Inrig J, Komers R, Heerspink HJL, Mercer A, Noronha IL, Radhakrishnan J, Rheault MN, Rote W, Trachtman H, Trimarchi H, Perkovic V; PROTECT investigators. IgA Nephropathy Patient Baseline Characteristics in the Sparsentan PROTECT Study. Kidney Int Rep. 2023 Mar 4;8(5):1043-1056. doi: 10.1016/j.ekir.2023.02.1086.

Chandra Y, Malani J, Irvine JH, Krishnan A, Johnson DW, Ritchie AG, Palmer SC. Incidence, treatment patterns and clinical outcomes associated with acute kidney injury in Fiji: a retrospective cohort study. J Nephrol. 2023 Jul;36(6):1689-1692. doi: 10.1007/s40620-023-01628-6. Epub 2023 Apr 24.

Charytan DM, Mahaffey KW, Jardine MJ, Cannon CP, Neal B, Lambers Heerspink HJ, Agarwal R, Bakris GL, de Zeeuw D, Levin A, Pollock C, Zhang H, Zinman B, Rosenthal N, Perkovic V, Di Tanna GL, Yu J, Rogers K, Arnott C, Wheeler DC. Cardiorenal protective effects of canagliflozin in CREDENCE according to glucose lowering. BMJ Open Diabetes Res Care. 2023 Jun;11(3):e003270. doi: 10.1136/bmjdrc-2022-003270.

Collister D, Pyne L, Bhasin AA, Ahmed SB, Smyth B, Herrington W, Jardine M, Walsh M. Sex and Gender in Randomized Controlled Trials of Adults Receiving Maintenance Dialysis: A Meta-epidemiologic Study. Am J Kidney Dis. 2023 May;81(5):575-582.e1. doi: 10.1053/j.ajkd.2022.10.015. Epub 2022 Dec 16.

Eckardt KU, Delgado C, Heerspink HJL, Pecoits-Filho R, Ricardo AC, Stengel B, Tonelli M, Cheung M, Jadoul M, Winkelmayer WC, Kramer H; Conference Participants. Trends and perspectives for improving quality of chronic kidney disease care: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2023 Nov;104(5):888-903. doi: 10.1016/j.kint.2023.05.013. Epub 2023 May 26.

Fletcher RA, Arnott C, Rockenschaub P, Schutte AE, Carpenter L, Vaduganathan M, Agarwal R, Bakris G, Chang TI, Heerspink HJL, Jardine MJ, Mahaffey KW, Neal B, Pollock C, Jun M, Rodgers A, Perkovic V, Neuen BL. Canagliflozin, Blood Pressure Variability, and Risk of Cardiovascular, Kidney, and Mortality Outcomes: Pooled Individual Participant Data From the CANVAS and CREDENCE Trials. J Am Heart Assoc. 2023 Jul 4;12(13):e028516. doi: 10.1161/JAHA.122.028516. Epub 2023 Jun 22.

Fletcher RA, Jongs N, Chertow GM, McMurray JJV, Arnott C, Jardine MJ, Mahaffey KW, Perkovic V, Rockenschaub P, Rossing P, Correa-Rotter R, Toto RD, Vaduganathan M, Wheeler DC, Heerspink HJL, Neuen BL. Effect of SGLT2 Inhibitors on Discontinuation of Renin-angiotensin System Blockade: A Joint Analysis of the CREDENCE and DAPA-CKD Trials. J Am Soc Nephrol. 2023 Dec 1;34(12):1965-1975. doi: 10.1681/ASN.0000000000000248. Epub 2023 Oct 25.

Gao F, Huang Z, Liang J, Kang Y, Ling Y, He Y, Chen J, Hong D, Zhang Z, Xu S, Wang A, Yan X, Liu J, Liu Y, Chen S, Chen J. Association of malnutrition with all-cause and cardiovascular mortality in patients with mild to severe chronic kidney disease undergoing coronary angiography: a large multicenter longitudinal study. Int Urol Nephrol. 2023 Dec;55(12):3225-3236. doi: 10.1007/s11255-023-03566-5. Epub 2023 Apr 27.

Ha JT, Scaria A, Andrade J, Badve SV, Birks P, Bota SE, Campain A, Djurdjev O, Garg AX, Harel Z, Hemmelgarn B, Hockham C, James MT, Jardine MJ, Lam D, Levin A, McArthur E, Ravani P, Shao S, Sood MM, Tan Z, Tangri N, Whitlock R, Gallagher M, Jun M. Safety and Effectiveness of Rivaroxaban Versus Warfarin Across GFR Levels in Atrial Fibrillation: A Population-Based Study in Australia and Canada. Kidney Med. 2023 May 16;5(7):100675. doi: 10.1016/j.xkme.2023.100675.

Heerspink HJL, Radhakrishnan J, Alpers CE, Barratt J, Bieler S, Diva U, Inrig J, Komers R, Mercer A, Noronha IL, Rheault MN, Rote W, Rovin B, Trachtman H, Trimarchi H, Wong MG, Perkovic V; PROTECT Investigators. Sparsentan in patients with IgA nephropathy: a prespecified interim analysis from a randomised, double-blind, active-controlled clinical trial. Lancet. 2023 May 13;401(10388):1584-1594. doi: 10.1016/S0140-6736(23)00569-X. Epub 2023 Apr 1.

Inker LA, Collier W, Greene T, Miao S, Chaudhari J, Appel GB, Badve SV, Caravaca-Fontán F, Del Vecchio L, Floege J, Goicoechea M, Haaland B, Herrington WG, Imai E, Jafar TH, Lewis JB, Li PKT, Maes BD, Neuen BL, Perrone RD, Remuzzi G, Schena FP, Wanner C, Wetzels JFM, Woodward M, Heerspink HJL; CKD-EPI Clinical Trials Consortium. A meta-analysis of GFR slope as a surrogate endpoint for kidney failure. Nat Med. 2023 Jul;29(7):1867-1876. doi: 10.1038/s41591-023-02418-0. Epub 2023 Jun 17.

Jun M, Scaria A, Andrade J, Badve SV, Birks P, Bota SE, Campain A, Djurdjev O, Garg AX, Ha J, Harel Z, Hemmelgarn B, Hockham C, James MT, Jardine MJ, Levin A, McArthur E, Ravani P, Shao S, Sood MM, Tan Z, Tangri N, Whitlock R, Gallagher M. Kidney function and the comparative effectiveness and safety of direct oral anticoagulants vs. warfarin in adults with atrial fibrillation: a multicenter observational study. Eur Heart J Qual Care Clin Outcomes. 2023 Sep 12;9(6):621-631. doi: 10.1093/ehjqcco/qcac069.

Kang A, Smyth B, Neuen BL, Heerspink HJL, Di Tanna GL, Zhang H, Arnott C, Hockham C, Agarwal R, Bakris G, Charytan DM, de Zeeuw D, Greene T, Levin A, Pollock C, Wheeler DC, Mahaffey KW, Perkovic V, Jardine MJ. The sodium-glucose cotransporter-2 inhibitor canagliflozin does not increase risk of non-genital skin and soft tissue infections in people with type 2 diabetes mellitus: A pooled post hoc analysis from the CANVAS Program and CREDENCE randomized double-blind trials. Diabetes Obes Metab. 2023 Aug;25(8):2151-2162. doi: 10.1111/dom.15091. Epub 2023 May 10.

Koshino A, Oshima M, Arnott C, Fletcher RA, Bakris GL, Jardine M, Mahaffey KW, Perkovic V, Pollock C, Heerspink HJL, Neuen BL. Effects of canagliflozin on liver steatosis and fibrosis markers in patients with type 2 diabetes and chronic kidney disease: A post hoc analysis of the CREDENCE trial. Diabetes Obes Metab. 2023 May;25(5):1413-1418. doi: 10.1111/dom.14978. Epub 2023 Feb 6.

Li Q, Huang H, Chen W, Shi S, Lu X, Lai W, Liang G, Wu J, Chen J, Liu J, Chen S, Wang AY, Liu Y. Trends in incidence and mortality of acute kidney disease following coronary angiography in the Chinese population: 2008–2017. Medicine Advances. 2023;1(2):123-132.

Lu X, Li Q, Deng J, Kang Y, Liang G, Deng L, Guo L, Ruan H, Peng Z, Li J, Tan N, Chen J, Liu J, Wang AY, Liu Y. Renal Insufficiency Increases the Combined Risk of Left Ventricular Hypertrophy and Dysfunction in Patients at High Risk of Cardiovascular Diseases. J Clin Med. 2023 Feb 24;12(5):1818. doi: 10.3390/jcm12051818.

Macdougall IC, Meadowcroft AM, Blackorby A, Cizman B, Cobitz AR, Godoy S, Jha V, Johansen KL, McMahon G, Obrador GT, Wong MG, Singh AK. Regional Variation of Erythropoiesis-Stimulating Agent Hyporesponsiveness in the Global Daprodustat Dialysis Study (ASCEND-D). Am J Nephrol. 2023;54(1-2):1-13. doi: 10.1159/000528696. Epub 2023 Feb 7.

Mathur M, Barratt J, Chacko B, Chan TM, Kooienga L, Oh KH, Sahay M, Suzuki Y, Wong MG, Yarbrough J, Xia J, Pereira BJG; ENVISION Trial Investigators Group. A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy. N Engl J Med. 2024 Jan 4;390(1):20-31. doi: 10.1056/NEJMoa2305635. Epub 2023 Nov 2.

Mehrotra R, Davison SN, Farrington K, Flythe JE, Foo M, Madero M, Morton RL, Tsukamoto Y, Unruh ML, Cheung M, Jadoul M, Winkelmayer WC, Brown EA; Conference Participants. Managing the symptom burden associated with maintenance dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney Int. 2023 Sep;104(3):441-454. doi: 10.1016/j.kint.2023.05.019. Epub 2023 Jun 7.

Mohebi R, Liu Y, Hansen MK, Yavin Y, Sattar N, Pollock CA, Butler J, Jardine M, Masson S, Heerspink HJL, Januzzi JL Jr. Insulin growth factor axis and cardio-renal risk in diabetic kidney disease: an analysis from the CREDENCE trial. Cardiovasc Diabetol. 2023 Jul 12;22(1):176. doi: 10.1186/s12933-023-01916-2.

Rheault MN, Alpers CE, Barratt J, Bieler S, Canetta P, Chae DW, Coppock G, Diva U, Gesualdo L, Heerspink HJL, Inrig JK, Kirsztajn GM, Kohan D, Komers R, Kooienga LA, Lieberman K, Mercer A, Noronha IL, Perkovic V, Radhakrishnan J, Rote W, Rovin B, Tesar V, Trimarchi H, Tumlin J, Wong MG, Trachtman H; DUPRO Steering Committee and DUPLEX Investigators. Sparsentan versus Irbesartan in Focal Segmental Glomerulosclerosis. N Engl J Med. 2023 Dec 28;389(26):2436-2445. doi: 10.1056/NEJMoa2308550. Epub 2023 Nov 3.

Rovin BH, Barratt J, Heerspink HJL, Alpers CE, Bieler S, Chae DW, Diva UA, Floege J, Gesualdo L, Inrig JK, Kohan DE, Komers R, Kooienga LA, Lafayette R, Maes B, Małecki R, Mercer A, Noronha IL, Oh SW, Peh CA, Praga M, Preciado P, Radhakrishnan J, Rheault MN, Rote WE, Tang SCW, Tesar V, Trachtman H, Trimarchi H, Tumlin JA, Wong MG, Perkovic V; DUPRO steering committee and PROTECT Investigators. Efficacy and safety of sparsentan versus irbesartan in patients with IgA nephropathy (PROTECT): 2-year results from a randomised, active-controlled, phase 3 trial. Lancet. 2023 Dec 2;402(10417):2077-2090. doi: 10.1016/S0140-6736(23)02302-4. Epub 2023 Nov 3.

Sun J, Wong MG. Haematuria in immunoglobulin a nephropathy: To be or not to be? Nephrology (Carlton). 2024 Feb;29(2):63-64. doi: 10.1111/nep.14272. Epub 2024 Jan 17.

Talbot B, Cass A, Walker R, Hooi L, Jardine M, Jun M, Rogers K, Sukkar L, Smyth B, Gallagher M. Comparing survival in patients with chronic kidney disease across three countries - Results from the study of heart and renal protection-extended review. Nephrology (Carlton). 2023 Jan;28(1):36-43. doi: 10.1111/nep.14127. Epub 2022 Nov 9.

Talbot B, Davies S, Burman J, Ritchie A, Snelling P, Lynch S, Park Y, Jones B, Garvey V, Jaure A, Jardine M, Perkovic V, Gallagher M, Brandwood A, Kaur N, Knight J. The Point-of-Care Peritoneal Dialysis System Early Evaluation Study (POC-PDEE): A pilot proof-of-principal study of the Ellen Medical Devices Point-of-Care affordable peritoneal dialysis system. Perit Dial Int. 2024 Jan 5:8968608231209850. doi: 10.1177/08968608231209850. Epub ahead of print.

Tran TB, Shah K, Rejuso A, Foote C, Sen S, Thom J, Arnold R. IPOS-R mobility score, utility and uptake: a retrospective clinical audit. Renal Society of Australasia Journal. 2023;19(1).

van der Hoek S, Jongs N, Oshima M, Neuen BL, Stevens J, Perkovic V, Levin A, Mahaffey KW, Pollock C, Greene T, Wheeler DC, Jardine MJ, Heerspink HJL. Glycemic Control and Effects of Canagliflozin in Reducing Albuminuria and eGFR: A Post Hoc Analysis of the CREDENCE Trial. Clin J Am Soc Nephrol. 2023 Jun 1;18(6):748-758. doi: 10.2215/CJN.0000000000000161. Epub 2023 Mar 31.

Wang M, Qin M, Wang AY, Zhao JW, Deng F, Han Y, Wang W. Clinical Manifestations and Risk Factors Associated with 14 Deaths following Swarm Wasp Stings in a Chinese Tertiary Grade A General Hospital: A Retrospective Database Analysis Study. J Clin Med. 2023 Sep 6;12(18):5789. doi: 10.3390/jcm12185789. PMID: 37762730; PMCID: PMC10532120.

Wang W, Wu S, Wang AY, Wu T, Luo H, Zhao JW, Chen J, Li Y, Ding H. Thrombomodulin activation driven by LXR agonist attenuates renal injury in diabetic nephropathy. Front Med (Lausanne). 2023 Jan 9;9:916620. doi: 10.3389/fmed.2022.916620.

Wu J, Cai H, Xia J, Zhang T, Yan J, Shao X, Wang AY, Shen J, Mou S. SGLT2i: Therapeutic options or contributing factors of contrast-induced acute kidney injury in the setting of non-diabetes? Pharmacol Res. 2023 Sep;195:106883. doi: 10.1016/j.phrs.2023.106883. Epub 2023 Aug 5.

Yeung J, Dix CHK, Ritchie AG, Kow M, Chen VMY. Tinzaparin for venous thromboembolism in patients with renal impairment: a single-centre, prospective pilot study. Intern Med J. 2023 Jan;53(1):68-73. doi: 10.1111/imj.15010. Epub 2022 Dec 5.

Yi TW, Smyth B, Di Tanna GL, Arnott C, Cardoza K, Kang A, Pollock C, Agarwal R, Bakris G, Charytan DM, de Zeeuw D, Heerspink HJL, Neal B, Wheeler DC, Cannon CP, Zhang H, Zinman B, Perkovic V, Levin A, Mahaffey KW, Jardine M; CREDENCE Trial Investigators. Kidney and Cardiovascular Effects of Canagliflozin According to Age and Sex: A Post Hoc Analysis of the CREDENCE Randomized Clinical Trial. Am J Kidney Dis. 2023 Jul;82(1):84-96.e1. doi: 10.1053/j.ajkd.2022.12.015. Epub 2023 Mar 7.

Young TK, Hockham C, Sukkar L, Kang A, Jun M, Foote C, Baker J, Rogers K, Zoungas S, Cass A, Sullivan D, Jardine MJ. Duration and effectiveness of glucose-lowering regimens in the real-world management of diabetes: Data from the Australian EXTEND45 Linked Cohort Study. Endocrine and Metabolic Science. 2023;12:1-51.

2020

Athavale, A., Morris, J., Jardine, M., Gallagher, M., Sen, S., Ritchie, A., Wang, AY. (2021) Acute interstitial nephritis and nephrogenic diabetes insipidus following treatment with sulfamethoxazole‐trimethoprim and temozolomide. Nephrology. 2021 Jan;26(1):12-4.

Barbieri S, Kemp J, Perez-Concha, O, Kotwal, S, Gallagher M, Ritchie A, Jorm, L. Benchmarking Deep Learning Architectures for Predicting Readmission to the ICU and Describing Patients-at-Risk. Sci Rep. 2020 Jan 24;10(1):1111. doi: 10.1038/s41598-020-58053-z

Flythe JE, Chang TI, Gallagher MP, Lindley E, Madero M, Sarafidis PA, Unruh ML, Wang AYM at el. Blood pressure and volume management in dialysis: conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Kidney International May 01, 2020 97(5), 861-876. doi.org/10.1016/j.kint.2020.01.046.

Foote C, Hockham C, Sukkar L, Campain A, Kang A, Young T, Cass A, Chow CK, Comino E, Gallagher M, Jan S, Knight J, Liu B, McNamara M, Peiris D, Pollock C, Sullivan D, Wong G, Zoungas S, Rogers K, Jun M, Jardine M. EXamining ouTcomEs in chroNic Disease in the 45 and Up Study (the EXTEND45 Study): Protocol for an Australian Linked Cohort Study. JMIR Research Protocols 2020;9(4): e15646.

Kang A, Sukkar L, Hockham C, Jun M, Young T, Scaria A, Foote C, Neuen BL, Cass A, Pollock C, Comino E, Lung T, Pecoits-Filho R, Rogers K, Jardine MJ; EXTEND45 STUDY STEERING COMMITTEE. Risk Factors for Incident Kidney Disease in Older Adults: an Australian Prospective Population-Based Study. Intern Med J. 2020 Oct 4.

Kotwal, S., Mehta, Y., Lee, V., Mallawarchchi, A., Ritchie, A., Wong, M., Makris, A., Badve, S., Yong, K., Jardine, M., Perkovic, V. (2020) GLOMERULAR DISEASE REGISTRY AND BIOBANK (GRIT). In NEPHROLOGY 2020 Nov 1 (Vol. 25, pp. 50-50). 111 RIVER ST, HOBOKEN 07030-5774, NJ USA: WILEY.

Kowal S, Coggan S, McDonald S, Talaulikar G, Cass A, Jan S, Polkinghorne K, Gray NA, Gallagher M on behalf of REDUCCTION Investigators. REDUcing the burden of dialysis Catheter ComplicaTIOns: a National approach (REDUCCTION) - design and baseline results. Kidney 360 August 2020, 1 (8) 746-754; DOI: https://doi.org/10.34067/KID.0001132020.

Lai C, Ying T, Wyburn K, Gallagher M, Ho J, Chadban S. Successful Kidney Transplantation in a Patient with Stable Multiple Myeloma - a case report. Internal Medicine Journal, 2020 Apr;50(4):492-494. doi: 10.1111/imj.14790.

Lin R, Toussaint ND, Gallagher M, Cass A, Kotwal S. Hospitalised fracture rates amongst patients with chronic kidney disease in Australia using data linkage. Nephrology (Carlton). 2020 Jun; 25(6):475-482. doi: 10.1111/nep.13681.

O'Brien Z, Finnis M, Gallagher M, Bellomo R. Early Treatment with Human Albumin Solution in Continuous Renal Replacement Patients. Blood Purification. 2020 Aug 20;1-9. doi: 10.1159/000509890.

O'Lone E, Kelly PJ, Masson P, Kotwal S, Gallagher M, Cass A, Craig JC, Webster AC. Incidence of ischaemic heart disease in men and women with end-stage kidney disease: a cohort study. Heart, Lung Circulation, 2020 Mar 23; S1443-9506(20)30096-2. doi: 10.1016/j.hlc.2020.03.002.

Ranasinghe I, Hossain S, Ali A, Horton D, Adams RJ, Aliprandi-Costa B, Bertilone C, Carneiro G, Gallagher M, Guthridge S, Kaambwa B, Kotwal S, O'Callaghan G, Scott I A, Visvanathan R, Woodman R J. SAFety, Effectiveness of care and Resource use among Australian Hospitals (SAFER Hospitals): a protocol for a population-wide cohort study of outcomes of hospital care. BMJ Open. 2020 Aug 20;10(8):e035446. doi: 10.1136/bmjopen-2019-035446.

Shaman A, Smyth B, Arnott C, Palmer SC, Mihailidou AS, Jardine MJ, Gallagher MP, Perkovic V, Jun M. Comparative efficacy and safety of blood pressure lowering pharmacotherapy in patients undergoing maintenance dialysis: a network meta-analysis of randomised controlled trials. CJASN. 2020 Aug 7;15(8):1129-1138. doi: 10.2215/CJN.12201019. Epub 2020 Jul 16.

Smyth B, Chan CT, Grieve SM, Puranik R, Zuo L, Hong D, Gray NA, De Zoysa JR, Scaria A, Gallagher M, Perkovic V, Jardine M. Predictors of Change in Left-Ventricular Structure and Function in a Trial of Extended Hours Hemodialysis. Journal of Cardiac Failure 26(6):482-491 01 Jun 2020. DOI: 10.1016/j.cardfail.2020.03.010.

Smyth B, Li Z, Gray N, Chan c, de Zoysa J, Hong D, Rogers K, Wang J, Cass A, Gallagher M, Perkovic V, Jardine M. ACTIVE Dialysis Study Investigators. No evidence of a legacy effect on survival following randomization to extended hours dialysis in the ACTIVE Dialysis trial. Nephrology (Carlton). 2020 Jun 5; e13737. doi: 10.1111/nep.13737.

Sukkar L, Kang A, Hockham C, Young T, Jun M, Foote C, Pecoits-Filho R, Neuen B, Rogers K, Pollock C, Cass A, Sullivan D, Wong G, Knight J, Peiris D, Gallagher M, Jardine M. Incidence and associations of chronic kidney disease in community participants with diabetes: A 5-year prospective analysis of the EXTEND45 study. Diabetes Care 2020 May;43(5):982-990. doi: 10.2337/dc19-1803.

Sukkar L, Kang A, Hockham C, Young T, Jun M, Foote C, Pecoits-Filho R, Neuen B, Rogers K, Pollock C, Cass A, Sullivan D, Wong G, Knight J, Peiris D, Gallagher M, Jardine M; EXTEND45 Study Steering Committee. Incidence and Associations of Chronic Kidney Disease in Community Participants With Diabetes: A 5-Year Prospective Analysis of the EXTEND45 Study. Diabetes Care. 2020 May;43(5):982-990. doi: 10.2337/dc19-1803. Epub 2020 Mar 11.

Tarragón, B., & Ye, N., & Gallagher, M., & Sen, S., Portolés, J., & Wang, A. (2020). Effect of high cut-off dialysis for acute kidney injury secondary to cast nephropathy in patients with multiple myeloma: a systematic review and meta-analysis. Clinical Kidney Journal. 10.1093/ckj/sfaa220.

The STARRT-AKI Investigators for the Canadian Critical Care Trials Group, the Australian and New Zealand Intensive Care Society Clinical Trials Group, the United Kingdom Critical Care Research Group, the Canadian Nephrology Trials Network, and the Irish Critical Care Trials Group (Gallagher M, member of Study Global Steering Committee and Writing Committee). Timing of Initiation of Renal-Replacement Therapy in Acute Kidney Injury. N Engl J Med. 2020 Jul 16;383(3):240-251 DOI: 10.1056/NEJMoa2000741.

Weisbord SD, Palevsky PM, Kaufman JS, Wu H, Androsenko M, Ferguson RE, Parikh CR, Bhatt DL, Gallagher M. Contrast-Associated Acute Kidney Injury and Serious Adverse Outcomes Following Angiography. JACC 2020 Mar 24; 75(11):1311-1320. doi: 10.1016/j.jacc.2020.01.023.

Xie Y, Baker J, Young T, Jun M, Sukkar L, Campain A, Kang A, Cass A, Hu J, Peiris D, Pollock C, Wong G, Zoungas S, Rogers K, Jardine M, Hockham C; EXTEND45 Steering Committee. Therapy Escalation Following an Elevated HbA<sub>1c</sub> in Adults Aged 45 Years and Older Living With Diabetes in Australia: A Real-World Observational Analysis. Diabetes Care. 2020 Nov;43(11):e185-e187.

Ye N, Xu Y, Bellomo R, Gallagher M, Wang AY. Effect of nephrology follow-up on long-term outcomes in patients with acute kidney injury: a systematic review and meta-analysis. Nephrology (Carlton). 2020 Aug; 25(8):607-615. doi: 10.1111/nep.13698.

Yeung, J., Dix, CH., Ritchie, AG., Kow, M., Chen, VM. (2020) Tinzaparin for venous thromboembolism in patients with renal impairment-a single‐centre, prospective pilot study. Internal medicine journal. 2020 Aug 12.

Zhang H, Rogers K, Sukkar L, Jun M, Kang A, Young T, Campain A, Cass A, Chow, CK, Comino E, Foote C, Gallagher M, Knight J, Liu B, Lung T, McNamara M, Peiris, D, Pollock C, Sullivan D, Wong G, Zoungas S, Jardine M, Hockham C; EXTEND45 Steering Committee. Prevalence, incidence and risk factors of diabetes in Australian adults aged ≥45 years: A cohort study using linked routinely-collected data. J Clin Transl Endocrinol. 2020 Nov 10.

Zimbudzi E, Lo C, Ranasinha S, Teede H, Usherwood T, Polkinghorne K, Fulcher G, Gallagher M, Jan S, Cass A, Walker R, Russell G, Johnson G, Kerr PG, Zoungas S. Health-related quality of life among patients with comorbid diabetes and kidney disease attending a co-designed integrated model of care: a longitudinal study. BMJ Open Diabetes Research & Care 2020 Jan;8(1):e000842. doi:10.1136/bmjdrc-2019-000842 [IF: 2.376 CIT:0]

2019

Cannon CP, Perkovic V, Agarwal R, Baldassarre J, Bakris G, Charytan DM, de Zeeuw D, Edwards R, Greene T, Heerspink HJL, Jardine MJ, Levin A, Li JW, Neal B, Pollock C, Wheeler DC, Zhang H, Zinman B, Mahaffey KW. Evaluating the Effects of Canagliflozin on Cardiovascular and Renal Events in Patients with Type 2 Diabetes and Chronic Kidney Disease According to Baseline HbA1c, Including Those with HbA1c <7%: Results From the CREDENCE Trial. Circulation. 2019 Nov 11. doi: 10.1161/CIRCULATIONAHA.119.044359. [Epub ahead of print]

Cory E. Goldstein, Charles Weijer, Monica Taljaard, Ahmed A. Al-Jaishi, Erika Basile, Jamie Brehaut, Charles L. Cook, Jeremy M. Grimshaw, Eduardo Lacson Jr, Craig Lindsay, Meg Jardine, Laura M. Dember, and Amit X. Garg. Ethical Issues in Pragmatic Cluster Randomized Trials in Dialysis Facilities. Am J Kidney Dis. 2019 Nov;74(5):659-666. doi: 10.1053/j.ajkd.2019.04.019. Epub 2019 Jun 19.

Graham-Brown MPM, Jardine MJ, Burton JO. Cardiovascular adaptations associated with exercise in patients on hemodialysis. Semin Dial. 2019 Jul;32(4):361-367. doi: 10.1111/sdi.12789. Epub 2019 Mar 24.

Gray NA, Zuo L, Hong D, Brendan S, Min J, De Zoysa J, Vo K, Howard K, Wang J, Lu C, Liu Z, Cass A, Perkovic V, Jardine M. Quality of life in caregivers compared with dialysis recipients: the Co-ACTIVE sub-study of the ACTIVE Dialysis trial. Nephrology 2019 Feb 5. doi: 10.1111/nep.13530. [Epub ahead of print].

Ha JT, Neuen BL, Cheng LP, Jun M, Toyama T, Gallagher MP, Jardine MJ, Sood MM, Garg AX, Palmer SC, Mark PB, Wheeler DC, Jha V, Freedman B, Johnson DW, Perkovic V, Badve SV. Benefits and harms of oral anticoagulant therapy in chronic kidney disease: a systematic review and meta-analysis. Annals of Internal Medicine 2019; DOI: 10.7326/M19-0087.

Heerspink HJL, Parving HH, Andress DL,...de Zeeuw D, on behalf of the SONAR Committees and Investigators (Gallagher M, Member of Investigator Team). Atrasentan and renal events in patients with type 2 diabetes and chronic kidney disease (SONAR): a double-blind, randomised, placebo-controlled trial. Lancet, 2019 May 11;393(10184):1937-1947.

Hong DQ, Wang AY, et al. Hyperuricemia and its related histopathological features on renal biopsy. BMC Nephrology, 2019;20:95. Impact factor 2.395.

Jardine MJ, Mahaffey KW, Perkovic V. Canagliflozin and Renal Outcomes in Diabetic Nephropathy. Reply. N Engl J Med. 2019 Sep 12;381(11):1089-1090. doi: 10.1056/NEJMc1909687. No abstract available.

Kenneth W. Mahaffey, Meg J. Jardine, Severine Bompoint, Christopher P. Cannon, Bruce Neal, Hiddo J.L. Heerspink, David M. Charytan, Robert Edwards, Rajiv Agarwal, George Bakris, Scott Bull, George Capuano, Dick de Zeeuw, Tom Greene, Adeera Levin, Carol Pollock, Tao Sun, David C. Wheeler, Yshai Yavin, Hong Zhang, Bernard Zinman, Norman Rosenthal, Barry M. Brenner and Vlado Perkovic on behalf of the CREDENCE study investigators. Canagliflozin and Cardiovascular and Renal Outcomes in Type 2 Diabetes and Chronic Kidney Disease in Primary and Secondary Cardiovascular Prevention Groups: Results from the Randomized CREDENCE Trial. Originally published July 11, 2019. Circulation 2019 Aug 27;140(9):739-750. doi: 10.1161/CIRCULATIONAHA.119.042007. Epub 2019 Jul 11.

Krishnasamy, R., Hawley, C.M., Jardine, M.J., Roberts, M.A., Cho, Y.J., Wong, M.G., Health, A., Nelson, C.L. Sen, S., Mount, P.F., Pascoe, E.M., Darssan, E.M., Vergara, L.A., Paul-Brent, P.A., Toussaint, N.D., Johnson, D.W., & Hutchison, C. A., Design and methods of the REMOVAL-HD study: a tRial Evaluating Mid cut-Off Value membrane clearance of Albumin and Light chains in HaemoDialysis patients. BMC Nephrol 19, 89 (2018). https://doi.org/10.1186/s12882-018-0883-8.

Lee EJ, Patel A, Acedillo RR, Bachynski JC, Barrett I, Basile E, Battistella M, Benjamin D, Berry D, Blake PG, Chan P, Bohm CJ, Clemens KK, Cook C, Dember L, Dirk JS, Dixon S, Fowler E, Getchell L, Gholami N, Goldstein C, Hahn E, Hogeterp B, Huang S, Hughes M, Jardine MJ, Kalatharan S, Kilburn S, Lacson E Jr, Leonard S, Liberty C, Lindsay C, MacRae JM, Manns BJ, McCallum J, McIntyre CW, Molnar AO, Mustafa RA, Nesrallah GE, Oliver MJ, Pandes M, Pandeya S, Parmar MS, Rabin EZ, Riley J, Silver SA, Sontrop JM, Sood MM, Suri RS, Tangri N, Tascona TJ, Thomas A, Wald R, Walsh M, Weijer C, Weir MA, Vorster H, Zimmerman D, Garg AX; Gardener's Grove Participants. Cultivating Innovative Pragmatic Cluster-Randomized Registry Trials Embedded in Hemodialysis Care: Workshop Proceedings from 2018. Can J Kidney Heal Dis. 2019; Dec 26;6:2054358119894394. doi: 10.1177/2054358119894394. eCollection 2019.

Lin J, Gallagher M, Wang AY. SOFA coagulation score and changes in platelet counts in severe acute kidney injury: analysis from the Randomised Evaluation of Normal versus Augmented Level（RENAL）study. Nephrology, 2019;24(5):518-25.

Lioufas N, Toussaint ND, Pedagogos E, Elder G, Badve SV, Pascoe E, Valks A, Hawley C; IMPROVE-CKD Writing Committee (M Jardine named Collaborator). Can we IMPROVE cardiovascular outcomes through phosphate lowering in CKD? Rationale and protocol for the IMpact of Phosphate Reduction On Vascular End-points in Chronic Kidney Disease (IMPROVE-CKD) study. BMJ Open. 2019 Feb 21;9(2):e024382. doi: 10.1136/bmjopen-2018-024382.

Liu Y, Hong D, Wang AY, Guo R, Smyth B, Liu J, Sun G, Chen S, Tan N, Jardine M, Brieger D, Shaman A, Islam S, Chen J, Gallagher M. Effects of intravenous hydration on risk of contrast induced nephropathy and in-hospital mortality in STEMI patients undergoing primary percutaneous coronary intervention: a systematic review and meta-analysis of randomized controlled trials. BMC Cardiovasc Disord. 2019 Apr 8;19(1):87. doi: 10.1186/s12872-019-1054-y.

Murugan R, Kerti SJ, Chang CCH, Gallagher M, Clermont G, Palevesky PM, Kellum JA, Bellomo R. Association of Net Ultrafiltration Rate With Mortality Among Critically Ill Adults With Acute Kidney Injury Receiving Continuous Venovenous Hemodiafiltration: A Secondary Analysis of the Randomized Evaluation of Normal vs Augmented Level (RENAL) of Renal Replacement Therapy Trial. JAMA Network Open, 2019 Jun 5;2(6):e195418. doi: 10.1001/jamanetworkopen.2019.5418.

O'Brien z, Cass A, Cole L, Finfer S, Gallagher M, McArthur C, McGuiness S, Myburgh J, Bellomo R, Martensson J and behalf of the RENAL Study Investigators. Sex and mortality in septic severe acute kidney injury. Journal of Critical Care 2019 Feb;49:70-76.

Quinto L, Sukkar L, Gallagher M. The effectiveness of corticosteroid compared to non-corticosteroid therapy for the treatment drug-induced acute interstitial nephritis: A systematic review. Internal Medicine Journal. 2019 May;49(5):562-569. doi: 10.1111/imj.14081.

Smyth B, Haber A, Trongtrakul K, Hawley C, Perkovic V, Woodward M, Jardine M. Representativeness of Randomized Clinical Trial Cohorts in End-stage Kidney Disease: A Meta-analysis. JAMA Intern Med. 2019 Jul 8. doi: 10.1001/jamainternmed.2019.1501. [Epub ahead of print]

Smyth B, Kotwal S, Gallagher M, Gray N, Polkinghorne K. Dialysis catheter management practices in Australia and New Zealand. Nephrology, 2019 Aug;24(8):827-834 doi: 10.1111/nep.13507.

Smyth B, Trongtrakul K, Haber A, Talbot B, Hawley C, Perkovic V, Woodward M, Jardine M. Inequities in the global representation of sites participating in large, multicentre dialysis trials: a systematic review. BMJ Glob Health. 2019 Nov 12;4(6):e001940. doi: 10.1136/bmjgh-2019-001940. eCollection 2019.

Sriravandrarajah A, Kotwal S, Sen S, McDonald S, Jardine M, Cass A, Gallagher M. Impact of supplemental private health insurance on dialysis and outcomes. Internal Medicine Journal, 2019 May 20. doi: 10.1111/imj.14375.

Sukkar L, Talbot B, Jun M, Dempsey E, Walker R, Hooi L, Cass A, Jardine M, Gallagher M. Protocol for the Study of Heart and Renal Protection-Extended Review: Additional 5-Year Follow-up of the Australian, New Zealand, and Malaysian SHARP Cohort. Can J Kidney Health Dis. 2019 Oct 14;6:2054358119879896. doi: 10.1177/2054358119879896. eCollection 2019.

Tadashi Toyama, Brendon L Neuen, Min Jun, Toshiaki Ohkuma, Bruce Neal, Meg Jardine, Hiddo L Heerspink, Muh Geot Wong, Toshiharu Ninomiya, Takashi Wada, Vlado Perkovic. Effect of SGLT2 inhibitors on cardiovascular, renal and safety outcomes in patients with type 2 diabetes mellitus and chronic kidney disease: a systematic review and meta-analysis. Diabetes, Obesity and Metabolism. 2019;21:1237-1250. Article DOI: 10.1111/dom.13648.

The STARRT-AKI investigators (including Gallagher, M, Wang, A. Y.). STandard versus Accelerated initiation of Renal Replacement Therapy in Acute Kidney Injury: Study Protocol for a Multi-National, Multi-Center, Randomized Controlled Trial. Canadian Journal of Kidney Health and Disease, 2019:6;1-11.

Toyama T, van den Broek-Best O, Wang AY, et al. Associations of Impaired Renal Function with Decline in Muscle Strength and Muscle Function in Older Men: Findings from the CHAMP Study. Journal of Gerontology: Medical Sciences, 2019; 4;74(11):1812-1820.

Trongtrakul K, Wang Y, Gallagher M. Acute Kidney Injury in Critically Ill Surgical Patients: Epidemiology, Risk Factors and Outcomes. Nephrology, 2019;24(1):39-46.

Wang AY, Konlawij T, Gallagher, M, et al. HMG-CoA reductase inhibitors (Statins) and acute kidney injury: a secondary analysis of renal study outcomes. Nephrology, 2019; 24(9):912-918.

Wang W, Fan SL, Wang AY, et al. Interaction between PLA2R1 and HLA-DQA1 variants contributes to the increased genetic susceptibility to membranous nephropathy in Western China. Nephrology 2019; 24(9):919-925.

Wong G; Hope RL; Howard K; Chapman JR; Castells A; Roger SD; Bourke MJ; Macaskill P; Turner R; Williams G; Lim WH; Lok CE; Diekmann F; Cross NB; Sen S; Allen RDM; Chadban SJ; Pollock CA; Tong A; Teixeira-Pinto A; Yang JYH; Williams N; Au EHK; Kieu A; James L; Craig JC. One-Time Fecal Immunochemical Screening for Advanced Colorectal Neoplasia in Patients with CKD (DETECT Study). Journal of the American Society of Nephrology. 30(6):1061-1072, 2019 06.

Wong MG, Wang AY, Jardine M, et al. Physical component Quality of life (QOL) reflects the impact of time and moderate chronic kidney disease, unlike SF-6D utility and mental component SF-36 QOL: an AUSDiab analysis. Nephrology, 2019;24(6):605-614.

Zhan Z, Smyth B, Toussaint ND, Gray NA, Zuo L, de Zoysa JR, Chan CT, Jin C, Scaria A, Hawley CM, Perkovic V, Jardine MJ (corresponding author), Zhang L. Effect of extended hours dialysis on markers of chronic kidney disease-mineral and bone disorder in the ACTIVE Dialysis study. BMC Nephrol. 2019 Jul 12;20(1):258. doi: 10.1186/s12882-019-1438-3.

Zhou Z, Jardine M, Perkovic V, Matthews DR, Mahaffey KW, de Zeeuw D, Fulcher G, Desai M, Oh R, Simpson R, Watts NB, Neal B. Canagliflozin and fracture risk in individuals with type 2 diabetes: results from the CANVAS Program. Diabetologia. 2019 Oct;62(10):1854-1867. doi: 10.1007/s00125-019-4955-5. Epub 2019 Aug 10.

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