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Endocrinology Research

The Department of Endocrinology is involved in local, national and international research. This includes studies in basic science, systems research and clinical research with patients in both the hospital and community. Areas of specific interest and expertise include bone disease, thyroid cancer, men's health and ageing.

Our Research Team

Dr Nic Kormas Head of Department and Senior Clinical Researcher (Obesity)
Professor Markus Seibel AM Research Lead, Senior Clinical Researcher (Bone and Mineral)
Professor Mark Cooper Senior Clinical Researcher (Bone and Adrenal)
Dr Kirtan Ganda Senior Clinical Researcher (Bone and Mineral)
Dr Ayanthi Wijerwardene Clinical Researcher (Thyroid cancer)
Dr Mawson Wang PhD candidate (Bone and Mineral).
Supervisor: Professor Markus Seibel

Selected Grants

Amount awarded Grant and project details
$1,500,000 NHMRC Investigator Grant, 2021-2025
Investigator Grant Leadership Lvl 3, Making the first fracture the last
Investigator: Seibel MJ
$639,166 NHMRC Ideas Grant, 2020-2025
Skeletal glucocorticoid signalling is required for high-fat diet-induced bone loss and obesity
Investigators: Zhou H (CIA), Swarbrick M (CIB), Kim S (CIC)

Our Publications

2023

Fani-Molky P, Bradley J, Cooper MS. Glucocorticoid-Induced Psychosis in Children and Adolescents: A Systematic Review. J Child Adolesc Psychopharmacol. 2023 Apr;33(3):78-90. doi: 10.1089/cap.2022.0077.
Lin M, Ridley L, Seibel MJ. Prediction of low DEXA T-scores by routine computed tomography body scans at different kilovoltage peaks. J Med Imaging Radiat Oncol. 2023 Sep;67(6):602-608. doi: 10.1111/1754-9485.13537. Epub 2023 May 17.
Luong R, Ribeiro RV, Rangan A, Naganathan V, Blyth F, Waite LM, Handelsman DJ, Le Couteur DG, Seibel MJ, Hirani V. Haem Iron Intake Is Associated with Increased Major Adverse Cardiovascular Events, All-Cause Mortality, Congestive Cardiac Failure, and Coronary Revascularisation in Older Men: The Concord Health and Ageing in Men Project. J Nutr Health Aging. 2023;27(7):559-570. doi: 10.1007/s12603-023-1945-6.
Macfarlane E, Cavanagh L, Fong-Yee C, Tuckermann J, Chen D, Little CB, Seibel MJ, Zhou H. Deletion of the chondrocyte glucocorticoid receptor attenuates cartilage degradation through suppression of early synovial activation in murine posttraumatic osteoarthritis. Osteoarthritis Cartilage. 2023 Sep;31(9):1189-1201. doi: 10.1016/j.joca.2023.04.009. Epub 2023 Apr 25.
Maleitzke T, Wiebe E, Huscher D, Spies CM, Tu J, Gaber T, Zheng Y, Buttgereit F, Seibel MJ, Zhou H. Transgenic disruption of endogenous glucocorticoid signaling in osteoblasts does not alter long-term K/BxN serum transfer-induced arthritis. Arthritis Res Ther. 2023 Aug 4;25(1):140. doi: 10.1186/s13075-023-03112-9.
Tran MH, van Zwieten A, Kiely KM, Blyth FM, Naganathan V, Le Couteur DG, Handelsman DJ, Seibel MJ, Waite LM, Cumming RG, Khalatbari-Soltani S. Intra-generational social mobility and mortality among older men in the Concord Health and Ageing in Men Project: A cohort study. SSM Popul Health. 2023 Dec 11;25:101581. doi: 10.1016/j.ssmph.2023.101581.
Tsai KH, Cooper MS. Recycling glucocorticoids: therapeutic implications of the 11β-HSD1 enzyme system. J Endocrinol. 2023 Aug 1;258(3):e220289. doi: 10.1530/JOE-22-0289.
Tsai KH, Shi H, Parungao RJ, Naficy S, Ding X, Ding X, Hew JJ, Wang X, Chrzanowski W, Lavery GG, Li Z, Issler-Fisher AC, Chen J, Tan Q, Maitz PK, Cooper MS, Wang Y. Skin 11β-hydroxysteroid dehydrogenase type 1 enzyme expression regulates burn wound healing and can be targeted to modify scar characteristics. Burns Trauma. 2023 Jan 20;11:tkac052. doi: 10.1093/burnst/tkac052.
Wang M, Seibel MJ. Approach to the Patient With Bone Fracture: Making the First Fracture the Last. J Clin Endocrinol Metab. 2023 Nov 17;108(12):3345-3352. doi: 10.1210/clinem/dgad345.
Wang M, Seibel MJ. Skin and bones: systemic mastocytosis and bone. Endocrinol Diabetes Metab Case Rep. 2023 May 11;2023(2):22-0408. doi: 10.1530/EDM-22-0408.
Wijewardene A, Bastard K, Wang B, Gild M, Luxford C, Gill A, Robinson B, Bullock M, Clifton-Bligh R. A Case Report of Poor Response to Selpercatinib in the Presence of a 632_633 RET Deletion. Thyroid. 2023 Jan;33(1):119-125. doi: 10.1089/thy.2021.0680.
Wijewardene A, Bastard K, Wang B, Gild M, Luxford C, Gill A, Robinson B, Bullock M, Clifton-Bligh R. Response to Szymczak et al. re: "A Case Report of Poor Response to Selpercatinib in the Presence of a 632_633 RET Deletion". Thyroid. 2023 Dec;33(12):1496-1497. doi: 10.1089/thy.2023.0325. Epub 2023 Nov 16.
Wijewardene A, Gill AJ, Gild M, Learoyd DL, Glover AR, Sywak M, Sidhu S, Roach P, Schembri G, Hoang J, Robinson B, Tacon L, Clifton-Bligh R. A Retrospective Cohort Study with Validation of Predictors of Differentiated Thyroid Cancer Outcomes. Thyroid. 2022 Oct;32(10):1201-1210. doi: 10.1089/thy.2021.0563. Epub 2022 Jun 30.
Wijewardene A, Hoang J, Maw AM, Gild M, Tacon L, Roach P, Schembri G, Chan D, Clifton-Bligh R. I-PET score: Combining whole body iodine and 18 F-FDG PET/CT imaging to predict progression in structurally or biochemically incomplete thyroid cancer. Clin Endocrinol (Oxf). 2023 Mar;98(3):436-446. doi: 10.1111/cen.14804. Epub 2022 Aug 15.
Wijewardene AA, Gild M, Tsang V. Prognostic Indexes for Anaplastic Thyroid Cancer. Clinical Thyroidology. 2023 Dec;35(12): 512-514. doi: 10.1089/ct.2023;35.512-514.
Wright FAC, Shu EC, Cumming RG, Naganathan V, Blyth FM, Hirani V, Le Couteur DG, Handelsman DJ, Seibel MJ, Waite LM, Stanaway FF. Oral health-related quality of life of older Australian men. Community Dent Oral Epidemiol. 2023 Oct;51(5):767-777. doi: 10.1111/cdoe.12754. Epub 2022 May 13.