A NSW Government website
The Plastic and Reconstructive Surgery Department carries out multi-facet basic science and clinical research in collaboration with other departments, including microsurgery teaching, surgical outcomes of complex facial reconstruction, patient reported outcome measure following mid-face reconstruction, non-melanoma skin cancers, melanoma.
| Amount awarded | Grant and project details |
|---|---|
| $25,000 | Perpetual IMPACT, 2021-2022 Evaluation of a Bioglass and polycaprolactone (PCL) derivative (actv-graft) as a bioactive scaffold for nasal dorsum reconstruction in an ovine model. Investigator: Ch'ng, S |
| Aivazian K, Ahmed T, El Sharouni MA, Stretch JR, Saw RPM, Spillane AJ, KF Shannon, Ch'ng S, Nieweg OE, Thompson JF, Lo N, Scolyer RA. Histological regression in melanoma: impact on sentinel lymph node status and survival. 2021 Nov;34(11):1999-2008. DOI: 10.1038/s41379-021-00870-2 |
| Aivazian K, Ahmed T, El Sharouni MA, Stretch JR, Saw RPM, Spillane AJ, KF Shannon, Ch'ng S, Nieweg OE, Thompson JF, Lo N, Scolyer RA. Correction to: Histological regression in melanoma: impact on sentinel lymph node status and survival. Mod Pathol. 2021 Nov;34(11):2091. DOI: 10.1038/s41379-021-00878-8 |
| Ch'ng S, Scolyer RA, Thompson JF. ASO Author Reflections: Surgical Resection May Improve the Outcome for Patients with Residual Metastatic Melanoma When Modern Systemic Therapies Have Not Achieved Complete Disease Control. Ann Surg Oncol. 2021 Oct;28(11):6124-6125. doi: 10.1245/s10434-021-10514-z |
| Ch'ng S, Uyulmaz S, Carlino MS, Pennington TE, Shannon KF, Rtshiladze M, Stretch JR, Nieweg OE, Varey AHR, Hsiao E, Kapoor R, da Silva IP, Lo SN, Spillane AJ, Scolyer RA, Long GV, Hong AM, Saw RPM, Thompson JF, Menzies AM. Re-defining the role of surgery in the management of patients with oligometastatic stage IV melanoma in the era of effective systemic therapies. Eur J Can. August 2021. 153,8-15 |
| Crouch G, Wong GL, Hong J, Varey AHR, Haddad R, Wang ZZ, Wykes J, Koutalistras N, Clark JR, Solomon M, Bannon P, McBride KE, Ch'ng S. Validated specialty‐specific models for multi‐disciplinary microsurgery training laboratories: a systematic review. ANZ J Surg. 2021;91(6);1110-1116 |
| Dawson R, Phung D, Every J, Gunawardena D, Low TH, Ch'ng S, Clark JR, Wykes J, Palme CE. Tracheostomy in free‐flap reconstruction of the oral cavity: can it be avoided? A cohort study of 187 patients. ANZ J Surg. 2021;91(6),1246-1250 |
| Every J, Subramaniam N, Dawson R, Ch'ng S, Low TH, Palme CE, Clark JR, Wykes J. Microvascular reconstruction of head and neck defects in the elderly. ANZ J Surg. 2021;91(5):969-974 |
| Li AT, Maw AM, Hsiao E, Ch'ng S, Long GV, Shannon KF, Morrison EJ. Bilateral facial neuritis associated with dabrafenib and trametinib after failure of neoadjuvant immunotherapy for stage III melanoma. ANZ J Surg. June 2021. DOI:10.1111/ans.16992 |
| Li AT, Vakharia K, Lo SN, Varey AHR, Carlino MS, Saw RPM, Shannon KF, Howle JR, Pennington TE, Stretch JR, Nieweg OE, Spillane AJ, Long GV, Menzies AM, Scolyer RA, Thompson JF, Ch'ng S. Survival outcomes of salvage metastasectomy after failure of modern-era systemic therapy for melanoma. Ann Surg Oncol. 2021 Oct;28(11):6109-6123. doi: 10.1245/s10434-021-10489-x |
| Mooney CP, Clark JR, Shannon KF, Palme CE, Ebrahimi A, Gao K, Ch'ng S, Elliott M, Gupta R, Low TH. The significance of regional metastasis location in head and neck cutaneous squamous cell carcinoma. Head Neck. 2021;43(9):2705-2711 |
| Petrides GA, Hicks G, Dunn M, Froggatt C, Wallace C, Howes D, Leinkram D, TH Low, Ch'ng S, Wykes J, Palme CE, Clark JR. Dentoalveolar outcomes in maxillary reconstruction: A retrospective review of 85 maxillectomy reconstructions. ANZ J Surg. June 2021. DOI: org/10.1111/ans.17001 |
| Rawson RV, Adhikari C, Bierman C, Lo SN, Shklovskaya E, Rozeman EA, Menzies AM, van Akkooi ACJ, Shannon KF, Gonzalez M, Guminski AD, Tetzlaff MT, Stretch JR, Eriksson H, van Thienen JV, Wouters MW, Haanen JBAG, Klop WMC, Zuur CL, van Houdt WJ, Nieweg OE, Ch'ng S, Rizos H, Saw RPM, Spillane AJ, Wilmott JS, Blank CU, Long GV, van de Wiel BA, Scolyer RA. Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma. Ann Oncol. 2021;32(6):766-777 |
| Regio Pereira A, Guitera P, Ferguson PM, Ch'ng S, Hirata S.Complex melanoma of the scalp: diagnosis and management aided by confocal microscopy. Australasian Journal of Dermatology. Accepted for publication October 2021 |
| Rozeman EA, Hoefsmit EP, Reijers ILM, Saw RPM, Versluis JM, Krijgsman O, Dimitriadis P, Sikorska K, van de Wiel BA, Eriksson H, Gonzalez M, Torres Acosta A, Grijpink-Ongering LG, Shannon K, Haanen JBAG, Stretch J, Ch'ng S, Nieweg OE, Mallo HA, Adriaansz S, Kerkhoven RM, Cornelissen S, Broeks A, Klop WMC, Zuur CL, van Houdt WJ, Peeper DS, Spillane AJ, van Akkooi ACJ, Scolyer RA, Schumacher TNM, Menzies AM, Long GV, Blank CU. Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma. Nat Med. 2021 Feb;27(2):256-263. doi: 10.1038/s41591-020-01211-7 |
| Versluis JM, Reijers ILM, Rozeman EA, Menzies AM, van Akkooi ACJ, Wouters MW, Ch'ng S, Saw RPM, Scolyer RA, van de Wiel BA, Schilling B, Long GV, Blank CU. Neoadjuvant ipilimumab plus nivolumab in synchronous clinical stage III melanoma. Eur J Can. 2021;148:51-57 |
| Yung A, Que MS, Lo S, Aggarwal S, Hong AM, Tin MM, Low TH, Clark JR, Gupta R, Ch'ng S. Validation of the American Joint Committee on Cancer Staging in Squamous Cell Carcinoma of the Vermilion Lip. Ann Surg Oncol. 2021 Jun;28(6):3092-3099. doi: 10.1245/s10434-020-09431-4 |
| Aivazian K, Ahmed T, El Sharouni MA, Stretch JR, Saw RPM, Spillane AJ, KF Shannon, Ch'ng S, Nieweg OE, Thompson JF, Lo N, Scolyer RA. Histological regression in melanoma: impact on sentinel lymph node status and survival. Mod Pathol. 2021. DOI: 10.1038/s41379-021-00870-2 |
| Ch'ng S, Uyulmaz S, Carlino MS, Pennington TE, Shannon KF, Rtshiladze M, Stretch JR, Nieweg OE, Varey AHR, Hsiao E, Kapoor R, da Silva IP, Lo SN, Spillane AJ, Scolyer RA, Long GV, Hong AM, Saw RPM, Thompson JF, Menzies AM. Re-defining the role of surgery in the management of patients with oligometastatic stage IV melanoma in the era of effective systemic therapies. Eur J Can. August 2021. 153,8-15. |
| Crouch G, Sinha S, Lo S, Saw RPM, Lee KK, Stretch J, Shannon K, Guitera P, Scolyer RA, Thompson JF, Ch'ng S. Clinical Outcomes following Surgical Treatment of Lentigo Maligna of the Head and Neck. Eur J Surg Oncol. 2021; 47 (5), 1145-1151. DOI: 10.1016/j.ejso.2020.09.028. |
| Crouch G, Wong GL, Hong J, Varey AHR, Haddad R, Wang ZZ, Wykes J, Koutalistras N, Clark JR, Solomon M, Bannon P, McBride KE, Ch'ng S. Validated specialty‐specific models for multi‐disciplinary microsurgery training laboratories: a systematic review. ANZ J Surg. 2021;91(6);1110-1116 |
| Dawson R, Phung D, Every J, Gunawardena D, Low TH, Ch'ng S, Clark JR, Wykes J, Palme CE. Tracheostomy in free‐flap reconstruction of the oral cavity: can it be avoided? A cohort study of 187 patients. ANZ J Surg. 2021;91(6),1246-1250 |
| Every J, Subramaniam N, Dawson R, Ch'ng S, Low TH, Palme CE, Clark JR, Wykes J. Microvascular reconstruction of head and neck defects in the elderly. ANZ J Surg. 2021;91(5):969-974 |
| Gonzalez M, Menzies A, Penington T, Saw RP, Spillane AJ, Stretch J, Ch'ng S, Nieweg OE, Rojas MC, Osorio M, Rawson RV, Ferguson PM, Rizos H, Lo S, Scolyer RA, Long GV. A phase II study of neoadjuvant pembrolizumab and lenvatinib for resectable stage III melanoma: The neopele study. Journal of Clinical Oncology. 2020 May;38(15_suppl):TPS10088-TPS10088 |
| Hasmat S, Mooney C, Gao K, Palme C, Ebrahimi A, Ch'ng S, Gupta R, Low TH, JR Clark. Regional Metastasis in Head and Neck Cutaneous Squamous Cell Carcinoma: An Update on the Significance of Extra-Nodal Extension and Soft Tissue Metastasis. Ann Surg Oncol. 2020 February;27(8) |
| Hayler R, Clark J, Croxson G, Coulson S, Hussain G, Ngo Q, Ch'ng S, Low TH. Sydney Facial Nerve Clinic: Experience of A Multidisciplinary Team. ANZ J Surg. 2020 Mar;90(5) |
| Holtkamp LHJ, Chakera AH, Fung S, Saw RPM, Lee KK, Ch'ng S, Gonzalez M, Thompson JF, Emmett L, Nieweg OE. Staging 18F-FDG PET/CT influences the treatment plan in melanoma patients with satellite or in-transit metastases. Melanoma Research. May 2020. DOI:10.1097/CMR.0000000000000666 (Published ahead of print) |
| Lee LP, Karagiannis P, Kim D, Thompson JF, Saw R, Lee KK, Ch'ng S. Lower Lip Reconstruction Revisited - Technical Solutions to Prevent Oral Incontinence and Maximize Vermilion Anterior Projection. Plast Reconstr Surg. July 2020. DOI: 10.1097/PRS.0000000000007194 (Published ahead of print) |
| Li AT, Maw AM, Hsiao E, Ch'ng S, Long GV, Shannon KF, Morrison EJ. Bilateral facial neuritis associated with dabrafenib and trametinib after failure of neoadjuvant immunotherapy for stage III melanoma. ANZ J Surg. June 2021. DOI:10.1111/ans.16992 |
| Li AT, Vakharia K, Lo SN, Varey AHR, Carlino MS, Saw RPM, Shannon KF, Howle JR, Pennington TE, Stretch JR, Nieweg OE, Spillane AJ, Long GV, Menzies AM, Scolyer RA, Thompson JF, Ch'ng S. Survival outcomes of salvage metastasectomy after failure of modern-era systemic therapy for melanoma. Ann Surg Oncol. June 2021. DOI: 10.1245/s10434-021-10489-x |
| Lo SN, Ma J, Scolyer RA, Haydu LE, Stretch JR, Saw RPM, Nieweg OE, Shannon KF, Spillane AJ, Ch'ng S, Mann GJ, Gershenwald JE, Thompson JF, Varey AHR. An improved risk-prediction calculator for sentinel node positivity in melanoma patients: the MIA nomogram. J Clin Oncol. June 2020;38(24). DOI:10.1200/JCO.19.02362 |
| Mooney CP, Clark JR, Shannon KF, Palme CE, Ebrahimi A, Gao K, Ch'ng S, Elliott M, Gupta R, Low TH. The significance of regional metastasis location in head and neck cutaneous squamous cell carcinoma. Head Neck. 2021;43(9):2705-2711 |
| Mooney, CP, Gao K, Clark JR, Gupta R, Shannon K, Palme CE, Ebrahimi A, Ch'ng S, Low TH. Soft Tissue Metastases in Head and Neck Cutaneous Squamous Cell Carcinoma. Laryngoscope. September 2020. DOI: 10.1002/lary.29064 |
| Petrides GA, Hicks G, Dunn M, Froggatt C, Wallace C, Howes D, Leinkram D, TH Low, Ch'ng S, Wykes J, Palme CE, Clark JR. Dentoalveolar outcomes in maxillary reconstruction: A retrospective review of 85 maxillectomy reconstructions. ANZ J Surg. June 2021. DOI: org/10.1111/ans.17001 |
| Rawson RV, Adhikari C, Bierman C, Lo SN, Shklovskaya E, Rozeman EA, Menzies AM, van Akkooi ACJ, Shannon KF, Gonzalez M, Guminski AD, Tetzlaff MT, Stretch JR, Eriksson H, van Thienen JV, Wouters MW, Haanen JBAG, Klop WMC, Zuur CL, van Houdt WJ, Nieweg OE, Ch'ng S, Rizos H, Saw RPM, Spillane AJ, Wilmott JS, Blank CU, Long GV, van de Wiel BA, Scolyer RA. Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma. Ann Oncol. 2021;32(6):766-777 |
| Rozeman EA, Hoefsmit EP, Reijers ILM, Saw RPM, Versluis JM, Krijgsman O, Dimitriadis P, Sikorska K, van de Wiel BA, Eriksson H, Gonzalez M, Torres Acosta A, Grijpink-Ongering LG, Shannon K, Haanen JBAG, Stretch J, Ch'ng S, Nieweg OE, Mallo HA, Adriaansz SA, Kerkhoven R, Cornelissen S, Broeks A, Klop WMC, Zuur CL, van Houdt W, Peeper DS, Spillane AJ, van Akkooi ACJ, Scolyer RA, Schumacher TNM, Menzies AM, Long GV, Blank CU. Survival and Biomarker Analyses from the OpACIN-neo and OpACIN Neoadjuvant Immunotherapy Trials in Stage III Melanoma. Nat Med. 2021. 27 (2), 256-263 |
| Versluis JM, Reijers ILM, Rozeman EA, Menzies AM, van Akkooi ACJ, Wouters MW, Ch'ng S, Saw RPM, Scolyer RA, van de Wiel BA, Schilling B, Long GV, Blank CU. Neoadjuvant ipilimumab plus nivolumab in synchronous clinical stage III melanoma. Eur J Can. 2021;148:51-57 |
| Yung A, Que MS, Lo S, Aggarwal S, Hong AM, Tin MM, Low TH, Clark JR, Gupta R, Ch'ng S. Validation of the American Joint Committee on Cancer Staging in Squamous Cell Carcinoma of the Vermilion Lip. Ann Surg Oncol. November 2020. DOI: 10.1245/s10434-020-09431-4 |
| Den Hondt M, Starr MW, Millett MC, Smyth J, Scolyer RA, Shannon KF, Thompson JF, Ch'ng S. Surgical management of the neck in patients with metastatic melanoma in parotid lymph nodes. J Surg Oncol. 2019 Dec;120(8):1462-1469. doi: 10.1002/jso.25732. Epub 2019 Oct 25. |
| Diefenbach RJ, Lee JH, Strbenac D, Yang JYH, Menzies AM, Carlino MS, Long GV, Spillane AJ, Stretch JR, Saw RPM, Thompson JF, Ch'ng S, Scolyer RA, Kefford RF, Rizos H. Analysis of the Whole-Exome Sequencing of Tumor and Circulating Tumor DNA in Metastatic Melanoma. Cancers (Basel). 2019 Nov 29;11(12). pii: E1905. doi: 10.3390/cancers11121905. |
| Hasmat S, Low TH, Krishnan A, Coulson S, Ch'ng S, Ashford BG, Croxson G, Clark JR. Chimeric Vastus Lateralis and Anterolateral Thigh Flap for Restoring Facial Defects and Dynamic Function following Radical Parotidectomy. Plast Reconstr Surg. 2019 Nov;144(5):853e-863e. doi: 10.1097/PRS.0000000000006183. |
| Mazzola F, Smithers F, Cheng K, Mukherjee P, Hubert Low TH, Ch'ng S, Palme CE, Clark JR. Time and cost-analysis of virtual surgical planning for head and neck reconstruction: A matched pair analysis. Oral Oncol. 2020 Jan;100:104491. doi: 10.1016/j.oraloncology.2019.104491. Epub 2019 Nov 30. |
| Mueller SA, Gauthier MA, Ashford B, Gupta R, Gayevskiy V, Ch'ng S, Palme CE, Shannon K, Clark JR, Ranson M, Cowley MJ. Mutational Patterns in Metastatic Cutaneous Squamous Cell Carcinoma. J Invest Dermatol. 2019 Jan 23. pii: S0022-202X(19)30024-7. doi: 10.1016/j.jid.2019.01.008. [Epub ahead of print] |