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Plastic and Reconstructive Surgery Research

The Plastic and Reconstructive Surgery Department carries out multi-facet basic science and clinical research in collaboration with other departments, including microsurgery teaching, surgical outcomes of complex facial reconstruction, patient reported outcome measure following mid-face reconstruction, non-melanoma skin cancers, melanoma.

Selected Grants

Amount awarded Grant and project details
$25,000 Perpetual IMPACT, 2021-2022
Evaluation of a Bioglass and polycaprolactone (PCL) derivative (actv-graft) as a bioactive scaffold for nasal dorsum reconstruction in an ovine model.
Investigator: Ch'ng, S

Our Publications

2021

Aivazian K, Ahmed T, El Sharouni MA, Stretch JR, Saw RPM, Spillane AJ, KF Shannon, Ch'ng S, Nieweg OE, Thompson JF, Lo N, Scolyer RA. Histological regression in melanoma: impact on sentinel lymph node status and survival. 2021 Nov;34(11):1999-2008. DOI: 10.1038/s41379-021-00870-2
Aivazian K, Ahmed T, El Sharouni MA, Stretch JR, Saw RPM, Spillane AJ, KF Shannon, Ch'ng S, Nieweg OE, Thompson JF, Lo N, Scolyer RA. Correction to: Histological regression in melanoma: impact on sentinel lymph node status and survival. Mod Pathol. 2021 Nov;34(11):2091. DOI: 10.1038/s41379-021-00878-8
Ch'ng S, Scolyer RA, Thompson JF. ASO Author Reflections: Surgical Resection May Improve the Outcome for Patients with Residual Metastatic Melanoma When Modern Systemic Therapies Have Not Achieved Complete Disease Control. Ann Surg Oncol. 2021 Oct;28(11):6124-6125. doi: 10.1245/s10434-021-10514-z 
Ch'ng S, Uyulmaz S, Carlino MS, Pennington TE, Shannon KF, Rtshiladze M, Stretch JR, Nieweg OE, Varey AHR, Hsiao E, Kapoor R, da Silva IP, Lo SN, Spillane AJ, Scolyer RA, Long GV, Hong AM, Saw RPM, Thompson JF, Menzies AM. Re-defining the role of surgery in the management of patients with oligometastatic stage IV melanoma in the era of effective systemic therapies. Eur J Can. August 2021. 153,8-15
Crouch G, Wong GL, Hong J, Varey AHR, Haddad R, Wang ZZ, Wykes J, Koutalistras N, Clark JR, Solomon M, Bannon P, McBride KE, Ch'ng S. Validated specialty‐specific models for multi‐disciplinary microsurgery training laboratories: a systematic review. ANZ J Surg. 2021;91(6);1110-1116
Dawson R, Phung D, Every J, Gunawardena D, Low TH, Ch'ng S, Clark JR, Wykes J, Palme CE. Tracheostomy in free‐flap reconstruction of the oral cavity: can it be avoided? A cohort study of 187 patients. ANZ J Surg. 2021;91(6),1246-1250
Every J, Subramaniam N, Dawson R, Ch'ng S, Low TH, Palme CE, Clark JR, Wykes J. Microvascular reconstruction of head and neck defects in the elderly. ANZ J Surg. 2021;91(5):969-974
Li AT, Maw AM, Hsiao E, Ch'ng S, Long GV, Shannon KF, Morrison EJ. Bilateral facial neuritis associated with dabrafenib and trametinib after failure of neoadjuvant immunotherapy for stage III melanoma. ANZ J Surg. June 2021. DOI:10.1111/ans.16992
Li AT, Vakharia K, Lo SN, Varey AHR, Carlino MS, Saw RPM, Shannon KF, Howle JR, Pennington TE, Stretch JR, Nieweg OE, Spillane AJ, Long GV, Menzies AM, Scolyer RA, Thompson JF, Ch'ng S. Survival outcomes of salvage metastasectomy after failure of modern-era systemic therapy for melanoma. Ann Surg Oncol. 2021 Oct;28(11):6109-6123. doi: 10.1245/s10434-021-10489-x
Mooney CP, Clark JR, Shannon KF, Palme CE, Ebrahimi A, Gao K, Ch'ng S, Elliott M, Gupta R, Low TH. The significance of regional metastasis location in head and neck cutaneous squamous cell carcinoma. Head Neck. 2021;43(9):2705-2711
Petrides GA, Hicks G, Dunn M, Froggatt C, Wallace C, Howes D, Leinkram D, TH Low, Ch'ng S, Wykes J, Palme CE, Clark JR. Dentoalveolar outcomes in maxillary reconstruction: A retrospective review of 85 maxillectomy reconstructions. ANZ J Surg. June 2021. DOI: org/10.1111/ans.17001
Rawson RV, Adhikari C, Bierman C, Lo SN, Shklovskaya E, Rozeman EA, Menzies AM, van Akkooi ACJ, Shannon KF, Gonzalez M, Guminski AD, Tetzlaff MT, Stretch JR, Eriksson H, van Thienen JV, Wouters MW, Haanen JBAG, Klop WMC, Zuur CL, van Houdt WJ, Nieweg OE, Ch'ng S, Rizos H, Saw RPM, Spillane AJ, Wilmott JS, Blank CU, Long GV, van de Wiel BA, Scolyer RA. Pathological response and tumour bed histopathological features correlate with survival following neoadjuvant immunotherapy in stage III melanoma. Ann Oncol. 2021;32(6):766-777
Regio Pereira A, Guitera P, Ferguson PM, Ch'ng S, Hirata S.Complex melanoma of the scalp: diagnosis and management aided by confocal microscopy. Australasian Journal of Dermatology. Accepted for publication October 2021
Rozeman EA, Hoefsmit EP, Reijers ILM, Saw RPM, Versluis JM, Krijgsman O, Dimitriadis P, Sikorska K, van de Wiel BA, Eriksson H, Gonzalez M, Torres Acosta A, Grijpink-Ongering LG, Shannon K, Haanen JBAG, Stretch J, Ch'ng S, Nieweg OE, Mallo HA, Adriaansz S, Kerkhoven RM, Cornelissen S, Broeks A, Klop WMC, Zuur CL, van Houdt WJ, Peeper DS, Spillane AJ, van Akkooi ACJ, Scolyer RA, Schumacher TNM, Menzies AM, Long GV, Blank CU. Survival and biomarker analyses from the OpACIN-neo and OpACIN neoadjuvant immunotherapy trials in stage III melanoma. Nat Med. 2021 Feb;27(2):256-263. doi: 10.1038/s41591-020-01211-7
Versluis JM, Reijers ILM, Rozeman EA, Menzies AM, van Akkooi ACJ, Wouters MW, Ch'ng S, Saw RPM, Scolyer RA, van de Wiel BA, Schilling B, Long GV, Blank CU. Neoadjuvant ipilimumab plus nivolumab in synchronous clinical stage III melanoma. Eur J Can. 2021;148:51-57
Yung A, Que MS, Lo S, Aggarwal S, Hong AM, Tin MM, Low TH, Clark JR, Gupta R, Ch'ng S. Validation of the American Joint Committee on Cancer Staging in Squamous Cell Carcinoma of the Vermilion Lip. Ann Surg Oncol. 2021 Jun;28(6):3092-3099. doi: 10.1245/s10434-020-09431-4